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31 Cards in this Set

  • Front
  • Back
Principal structure is?
the skin
skin is what 4 things
1)largest organ in the body
2)accounts for aprox. 15% of body weight
3)has the surface area of 8-11 sq. feet
4)average thickness of 2-4mm
functions of skin (8)
1)protection- U.V, Langerhans cells(bacteria)
2)sensation- temperature; vibratio; presure; pain;touch(haptics)
3)heat regulation- sweat; dermal blood vessel dialation; erector pili muscle
4)prevents fluid loss
5)storage and synthesis- storage for fats and water; synthesis of vitamin D
6)execretion- sweat contains urea (1/30th)of Urine
7)absorbtion-transdermal medicines by way of an adhesive patch
8)aesthetics
skin layers
a)epidermis-thin top layer(.05 eyelid, 1.5mm soles of feet)
b)dermis-thick deeper layer(.3 eyelid, 3mm on the back)
epidermis
-"epi" meaning over
-contains no blood vessels and is nourished by diffusion from the dermis
dermis (layers)
-made up of stratified squamus epithelial cells
-5 sublayers:(top to bottom)
*Stratum corneum-toughest (dead)
*Stratum lucidum- in palms/soles only
*stratum granulosum
*stratum spinosum
*stratum basale- contains the melanocytes
Cher Likes Getting Skin Botoxed
cells are formed in the ?
stratum basale through mitosis and move up the strata as they change sape and become filled with keratin
keratin
tough water proof protein in the epidermis hair and nails
Dermis (function and structure)
-connective tissue
Function:-cushions the body from stress and strain
-contains nerve receptors; blood and lymphatic vessels; sweat and oi glands
Structure:-superficial area:Papillary region
-deep thicker area:recticular region
papilary region
made of loose connective tissues has projections called papillae that extend toward the epidermis. these papillae strengthen the bondage between the layers
dermal papillae (location?)
in the fingertips, soles of feet and toe form friction ridges(helping in grasp)
Fingerprints-the unique pattern of friction ridges
reticular region
made up of dense connective tissue(collagen, elastic and reticular fibers), giving the dermis its properties of strength, extensibility and elasticity. (these break down causing wrinkles)
hair
a.hair follicle- live part of hair located in the dermis
b.hair shaft- visible part of hair (dead)
c.hair root- part of hair that is not seen
hair loss
alopecia
alopecia androgenica
male pattern baldness (genitic predisposition)
nail body
visible part of nail
nail bed
dermal tissue under the body
sudoriferous=?
sweat
eccrine
thin watery sweat (all over body)
apocrine
thicker (axillary and inguinal), begins in adolescence. Bacteria waste=body odor
sebaceous
-secretes oil(sebum) which is natures skin cream. keeps skin soft and aides in the waterproofing of skin.
-increases 5x in adolescence
-attached to every hair follicle
receptors
-sensory neurons
a.hir folicle endings--hair displacement
b.Ruffini endings--pressure on skin
c.Krause's end bulb--pressure(lips,tongue,genitals)
d.Pacinan corpuscle--vibration(150-300 hz range)
e.Meissner's corpuscle--vibration(20-40 hz range)
f.Free nerve endings--mechanical,thermal,noxious(pain)
nocioceptors-
specific for pain. Vary in consentrations depending on location
MRSA
(INFECTION)
*a strain of staph that devoloped in hospitals from overuse of anti-biotic materials.
*signs- small red papules that turn into deep absecesses, can remain in the skin. But, can travel to joints,bones,bloo etc. Can be life threatening.
*risk factors-hospital/nursing
-recent antiibiotic therapy
-invasive devices
-young age
-contact sports
-immunosupressed
-sharing razors
-prison innmates
*treatment: vancomycin
*prevention: good hygine
Atopic Dermatitis (eczema)
(auto immune)
*chronic inflamation of the skin
*signs- itching red rash with papules that ooze. Most often apear onn extremities also on eyes/lids
*risk- family history
-stress and emotion(will not cause it)
*treatments:reduce stress, over the counter meds like anti-itch cream and omega 3's
Psoriasis
-T-lymphacytes infiltrate the skin causing rapid motility of epidermal cells to the surface
*signs-red patches of skin covered in scales(plaque). Dry cracked skin with bleeding
*risks- genetics,HIV,stress,smoking,obesity
*treatment- symptomatic(toipical and oral meds, vitamin D,sunlight(small amounts),stress reduction
Scleroderma-
*a rare disease that hardens the skin and connective tissue caused by inflamation and over produce of collegen proteins
*Types 1.Localized-skin only
2.systemic-skin & organs(can be fatal)
*signs- skin get tight and shiny,difficulty bending fingers
*risk factors- NONE
*treatments:symptomatic relief
basal cell carcinoma
*the most common skin cancer,rarely fatal,can cause tissue damage.
*signs- a white/waxy bump with blood vesels in it.(face)
*risks- fair skin,family history,male,immune supressing drugs
*treatment- surgery,freezing,laser,topical drugs(Tazorac-used for acne)
squamus cell carcinoma-
slow growing,from epidermis. Can matastisize,but rarely.Faster than Basel cell.
*signs- small redish bumps/patches,sore tht does not heal
*treatment- smae as Basal cell
Malignant Melanoma
*aggressive malignancy,2-4% of skin cancers but 99% deadly
New cases this year-60,000
Deaths- 8,000
*signs- mole that meets one or more of the ABCDE
*treatment:surgery, chemo,radiation
ABCDE=
A-asymetry
B-border
C-color(change)
D-diameter
E-evolving any change