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31 Cards in this Set
- Front
- Back
Principal structure is?
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the skin
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skin is what 4 things
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1)largest organ in the body
2)accounts for aprox. 15% of body weight 3)has the surface area of 8-11 sq. feet 4)average thickness of 2-4mm |
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functions of skin (8)
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1)protection- U.V, Langerhans cells(bacteria)
2)sensation- temperature; vibratio; presure; pain;touch(haptics) 3)heat regulation- sweat; dermal blood vessel dialation; erector pili muscle 4)prevents fluid loss 5)storage and synthesis- storage for fats and water; synthesis of vitamin D 6)execretion- sweat contains urea (1/30th)of Urine 7)absorbtion-transdermal medicines by way of an adhesive patch 8)aesthetics |
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skin layers
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a)epidermis-thin top layer(.05 eyelid, 1.5mm soles of feet)
b)dermis-thick deeper layer(.3 eyelid, 3mm on the back) |
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epidermis
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-"epi" meaning over
-contains no blood vessels and is nourished by diffusion from the dermis |
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dermis (layers)
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-made up of stratified squamus epithelial cells
-5 sublayers:(top to bottom) *Stratum corneum-toughest (dead) *Stratum lucidum- in palms/soles only *stratum granulosum *stratum spinosum *stratum basale- contains the melanocytes Cher Likes Getting Skin Botoxed |
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cells are formed in the ?
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stratum basale through mitosis and move up the strata as they change sape and become filled with keratin
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keratin
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tough water proof protein in the epidermis hair and nails
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Dermis (function and structure)
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-connective tissue
Function:-cushions the body from stress and strain -contains nerve receptors; blood and lymphatic vessels; sweat and oi glands Structure:-superficial area:Papillary region -deep thicker area:recticular region |
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papilary region
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made of loose connective tissues has projections called papillae that extend toward the epidermis. these papillae strengthen the bondage between the layers
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dermal papillae (location?)
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in the fingertips, soles of feet and toe form friction ridges(helping in grasp)
Fingerprints-the unique pattern of friction ridges |
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reticular region
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made up of dense connective tissue(collagen, elastic and reticular fibers), giving the dermis its properties of strength, extensibility and elasticity. (these break down causing wrinkles)
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hair
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a.hair follicle- live part of hair located in the dermis
b.hair shaft- visible part of hair (dead) c.hair root- part of hair that is not seen |
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hair loss
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alopecia
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alopecia androgenica
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male pattern baldness (genitic predisposition)
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nail body
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visible part of nail
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nail bed
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dermal tissue under the body
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sudoriferous=?
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sweat
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eccrine
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thin watery sweat (all over body)
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apocrine
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thicker (axillary and inguinal), begins in adolescence. Bacteria waste=body odor
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sebaceous
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-secretes oil(sebum) which is natures skin cream. keeps skin soft and aides in the waterproofing of skin.
-increases 5x in adolescence -attached to every hair follicle |
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receptors
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-sensory neurons
a.hir folicle endings--hair displacement b.Ruffini endings--pressure on skin c.Krause's end bulb--pressure(lips,tongue,genitals) d.Pacinan corpuscle--vibration(150-300 hz range) e.Meissner's corpuscle--vibration(20-40 hz range) f.Free nerve endings--mechanical,thermal,noxious(pain) |
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nocioceptors-
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specific for pain. Vary in consentrations depending on location
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MRSA
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(INFECTION)
*a strain of staph that devoloped in hospitals from overuse of anti-biotic materials. *signs- small red papules that turn into deep absecesses, can remain in the skin. But, can travel to joints,bones,bloo etc. Can be life threatening. *risk factors-hospital/nursing -recent antiibiotic therapy -invasive devices -young age -contact sports -immunosupressed -sharing razors -prison innmates *treatment: vancomycin *prevention: good hygine |
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Atopic Dermatitis (eczema)
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(auto immune)
*chronic inflamation of the skin *signs- itching red rash with papules that ooze. Most often apear onn extremities also on eyes/lids *risk- family history -stress and emotion(will not cause it) *treatments:reduce stress, over the counter meds like anti-itch cream and omega 3's |
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Psoriasis
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-T-lymphacytes infiltrate the skin causing rapid motility of epidermal cells to the surface
*signs-red patches of skin covered in scales(plaque). Dry cracked skin with bleeding *risks- genetics,HIV,stress,smoking,obesity *treatment- symptomatic(toipical and oral meds, vitamin D,sunlight(small amounts),stress reduction |
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Scleroderma-
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*a rare disease that hardens the skin and connective tissue caused by inflamation and over produce of collegen proteins
*Types 1.Localized-skin only 2.systemic-skin & organs(can be fatal) *signs- skin get tight and shiny,difficulty bending fingers *risk factors- NONE *treatments:symptomatic relief |
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basal cell carcinoma
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*the most common skin cancer,rarely fatal,can cause tissue damage.
*signs- a white/waxy bump with blood vesels in it.(face) *risks- fair skin,family history,male,immune supressing drugs *treatment- surgery,freezing,laser,topical drugs(Tazorac-used for acne) |
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squamus cell carcinoma-
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slow growing,from epidermis. Can matastisize,but rarely.Faster than Basel cell.
*signs- small redish bumps/patches,sore tht does not heal *treatment- smae as Basal cell |
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Malignant Melanoma
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*aggressive malignancy,2-4% of skin cancers but 99% deadly
New cases this year-60,000 Deaths- 8,000 *signs- mole that meets one or more of the ABCDE *treatment:surgery, chemo,radiation |
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ABCDE=
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A-asymetry
B-border C-color(change) D-diameter E-evolving any change |