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61 Cards in this Set
- Front
- Back
skeletal system
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made up of many different types of connective tissue
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supporting connective tissue
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cartilage and bone
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cartilage
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consists of a firm gel matrix that contains complex polysaccharides called chondoitin sulfates
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chondrocytes
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(cartilage cells), only cells found within cartilage matrix
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lacunae
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small chambers in which cartilage cells live
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cartilage grows by two mechanisms
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1) appositional growth - growth from the surface
2) interstitial gowth - growth from within |
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hyaline
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function: provides support and reduces friction between bony surfaces
location: ribes and sternum; joints; supports larynx, trachea and bronchi; nasal septum |
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elastic
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function: provides support but tolerates distortion
location: ear; epiglottis; auditory canal; larynx |
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fibrocartilage
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resists compression, prevents bone to bone contact and limits relative movement
location: knee joint, pubic bone, and intervertebral discs |
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bone
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osseous tissue
- specialized cell - protein fibers - fluid ground substance |
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skeletal system functions
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1) structural support for body
2) storage of minerals (calcium) and lipids (yellow marrow) 3) hemopoiesis - production of blood cells within red marrow 4) protection of delicate tissues and organs 5) leverage |
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bone matrix
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major mass of bone, 98%
- calcium hydroxyapatite: inorgainc crystals that give bone its compressional strength - collagen fibers: give bone tensil strength |
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bone cells
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2% of bone mass
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osteocyte
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mature bone cell that maintains bone matrix
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osteoblast
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immature bone cell that secretes organic components of matrix
- make new bone |
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osteoprogenitor cell
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stem cell whose divisions produce osteoblasts
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osteoclast
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multinucleate cell that secretes acids and enzymes to dissolve bone matrix
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compact bone
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aka lamellar bone; dense, solid bone
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compact bone arrangement
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- osteocyets arranged in lamellae layers arranged around central canal
- osteocytes occupy lacunae spaces in which canaliculi radiate from - osteon basic functional unit - perforating canals run perpendicular |
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spongy bone arrangement
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parallel lamellae form thin, braching plates called trabeculae
- no osteons |
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periosteum
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connective tissue layer covering outer surface of bone; functions:
1) isolate and protect bone froms surrounding tissue 2) provide route and place of attachment for circulatory and nerve supply 3) actively participates in bone growth and repair 4) attaches bone to connective tissue network of deep fascia |
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endosteum
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lines medullary cavity inside bone - contains osteoprogenitor cells, covers trabeculae of spongy bone and lines inner surfaces of central canals
function: active during bone growth and repair |
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osteogenesis
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bone formation
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ossification
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process of replacing other tissues with bone
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mesenchyme
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embryonic/fetal connective tissue
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calcification
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deposition of calcium salts within tissue
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intramembranous ossification
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aka dermal ossification, begins when mesenchymal cells differentiate into osteoblasts inthin embryonic or fibrous connective tissues
- occurs in dermis - bones called dermal or membranous bones ex) skull, collarbone, jaw, kneecap |
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endochondral ossification
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begins with formation of hyaline cartilage
ex) limb development, long bones |
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nutrient artery and vein
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penetrate the shaft to reach the medullary cavity
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metaphyseal vessels
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supply blood to the inner diaphyseal surface of each epiphyseal cartilage
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epiphyseal vessels
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run through the numerous smaller foramina opening in the epiphyseal ends; supply osseous tissue and medullary cavities of epiphyses
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periosteal vessels
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incorporated into developing bone surface and provide blood to superficial osteons of shaft
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parathyroid hormone (PTH)
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stimulates osteoclast and osteoblast activity, increases rate of calcium absorption along intestine and reduces rate of calcium loss in urine
- requires calcitrol |
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C thyrocytes (C cells)
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within thyroid of children an pregnant women secrete calcitonin which inhibits osteoclasts and increases rate of calcium loss in urine
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calcitriol
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active form of vitamin D synthesized in kidneys
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Fosamax
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Generic Name: Alendronate Sodium
Drug Class: Bisphosphonate - Osteoporosis Agent |
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osteopenia
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inadequate ossification; everyone becomes slightly osteopenic as they age
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osteoporosis
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reduction in bone mass and microstructural changes that compromise normal function and increase susceptibility to fractures
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number of bones in human skeleton
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206
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flat bone
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thin, roughly parallel surfaces of compact bone; strong and light bones; provide protection for underlying soft tissue; offer surface area for muscle attachment
ex) skull bones, sternum, and scapula |
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pneumatized bones
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hollow bones that contain many pockets
ex) ethmoid |
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irregular bone
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complex shapes with short, flat, notched or ridged surfaces
ex) skull bones and vertebrae |
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short bones
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box-like appearance, external surface covered by compact bone, interior spongy bone
ex)carpals and tarsals |
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sesamoid bone
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small, round and flat; develop inside tendon; near a joint
ex) patella |
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long bone
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long and slender; diaphysis, 2 metaphyses, 2 epiphyses, marrow cavity
ex) humerus, radius and ulna, femur, and tibia and fibula |
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axial skeleton
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- acts as framework that suppports and protects organs within dorsal and ventral body cavities
- provides attachment for major body muscles - forms longitudinal axis of body - comprises roughly 40% (80) of bones |
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skull components
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associated bones, cranium, and face
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associated bones
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7
- 6 auditory ossicles - hyoid bone |
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cranium
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8
- 1 occipital bone - 2 parietal bones - 1 frontal bone - 2 temporal bones - 1 sphenoid - 1 ethmoid |
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face
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14
- 2 maxillae - 2 palantine - 2 nasal bones - 2 inferior nasal conchae - 2 zygomatic bones - 2 lacrimal bones - 1 vomer - 1 mandible |
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primary curve
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fetal curve, present from time of fetal development
- thoracic - sacral |
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secondary curve
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curve because of what we do
- cervical because lift head - lumbar because stand upright |
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cervical
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- secondary cure
- 7 vertebrae |
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thoracic
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- primary curve
- 12 vertebrae |
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lumbar
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- secondary curve
- 5 vertebrae |
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sacral
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- primary curve
- 5 fused vertebrae |
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coccygeal
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3-5 fused vertebrae
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kyphosis
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normal thoracic curve becomes exaggerated posteriorly, producing a roundback appearance
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lordosis
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"sway back," both abdomen and butt protrude abnormally
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scoliosis
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abnormal lateral curvature of the spine; most common distortion of spine
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appendicular skeleton
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-gives individuals control over environment
- changes body's position in space - provides mobility - comprises 60% of bones (126) |