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61 Cards in this Set

  • Front
  • Back
skeletal system
made up of many different types of connective tissue
supporting connective tissue
cartilage and bone
cartilage
consists of a firm gel matrix that contains complex polysaccharides called chondoitin sulfates
chondrocytes
(cartilage cells), only cells found within cartilage matrix
lacunae
small chambers in which cartilage cells live
cartilage grows by two mechanisms
1) appositional growth - growth from the surface
2) interstitial gowth - growth from within
hyaline
function: provides support and reduces friction between bony surfaces

location: ribes and sternum; joints; supports larynx, trachea and bronchi; nasal septum
elastic
function: provides support but tolerates distortion

location: ear; epiglottis; auditory canal; larynx
fibrocartilage
resists compression, prevents bone to bone contact and limits relative movement

location: knee joint, pubic bone, and intervertebral discs
bone
osseous tissue
- specialized cell
- protein fibers
- fluid ground substance
skeletal system functions
1) structural support for body
2) storage of minerals (calcium) and lipids (yellow marrow)
3) hemopoiesis - production of blood cells within red marrow
4) protection of delicate tissues and organs
5) leverage
bone matrix
major mass of bone, 98%
- calcium hydroxyapatite: inorgainc crystals that give bone its compressional strength
- collagen fibers: give bone tensil strength
bone cells
2% of bone mass
osteocyte
mature bone cell that maintains bone matrix
osteoblast
immature bone cell that secretes organic components of matrix
- make new bone
osteoprogenitor cell
stem cell whose divisions produce osteoblasts
osteoclast
multinucleate cell that secretes acids and enzymes to dissolve bone matrix
compact bone
aka lamellar bone; dense, solid bone
compact bone arrangement
- osteocyets arranged in lamellae layers arranged around central canal
- osteocytes occupy lacunae spaces in which canaliculi radiate from
- osteon basic functional unit
- perforating canals run perpendicular
spongy bone arrangement
parallel lamellae form thin, braching plates called trabeculae
- no osteons
periosteum
connective tissue layer covering outer surface of bone; functions:
1) isolate and protect bone froms surrounding tissue
2) provide route and place of attachment for circulatory and nerve supply
3) actively participates in bone growth and repair
4) attaches bone to connective tissue network of deep fascia
endosteum
lines medullary cavity inside bone - contains osteoprogenitor cells, covers trabeculae of spongy bone and lines inner surfaces of central canals
function: active during bone growth and repair
osteogenesis
bone formation
ossification
process of replacing other tissues with bone
mesenchyme
embryonic/fetal connective tissue
calcification
deposition of calcium salts within tissue
intramembranous ossification
aka dermal ossification, begins when mesenchymal cells differentiate into osteoblasts inthin embryonic or fibrous connective tissues
- occurs in dermis
- bones called dermal or membranous bones
ex) skull, collarbone, jaw, kneecap
endochondral ossification
begins with formation of hyaline cartilage
ex) limb development, long bones
nutrient artery and vein
penetrate the shaft to reach the medullary cavity
metaphyseal vessels
supply blood to the inner diaphyseal surface of each epiphyseal cartilage
epiphyseal vessels
run through the numerous smaller foramina opening in the epiphyseal ends; supply osseous tissue and medullary cavities of epiphyses
periosteal vessels
incorporated into developing bone surface and provide blood to superficial osteons of shaft
parathyroid hormone (PTH)
stimulates osteoclast and osteoblast activity, increases rate of calcium absorption along intestine and reduces rate of calcium loss in urine
- requires calcitrol
C thyrocytes (C cells)
within thyroid of children an pregnant women secrete calcitonin which inhibits osteoclasts and increases rate of calcium loss in urine
calcitriol
active form of vitamin D synthesized in kidneys
Fosamax
Generic Name: Alendronate Sodium

Drug Class: Bisphosphonate - Osteoporosis Agent
osteopenia
inadequate ossification; everyone becomes slightly osteopenic as they age
osteoporosis
reduction in bone mass and microstructural changes that compromise normal function and increase susceptibility to fractures
number of bones in human skeleton
206
flat bone
thin, roughly parallel surfaces of compact bone; strong and light bones; provide protection for underlying soft tissue; offer surface area for muscle attachment
ex) skull bones, sternum, and scapula
pneumatized bones
hollow bones that contain many pockets
ex) ethmoid
irregular bone
complex shapes with short, flat, notched or ridged surfaces
ex) skull bones and vertebrae
short bones
box-like appearance, external surface covered by compact bone, interior spongy bone
ex)carpals and tarsals
sesamoid bone
small, round and flat; develop inside tendon; near a joint
ex) patella
long bone
long and slender; diaphysis, 2 metaphyses, 2 epiphyses, marrow cavity
ex) humerus, radius and ulna, femur, and tibia and fibula
axial skeleton
- acts as framework that suppports and protects organs within dorsal and ventral body cavities
- provides attachment for major body muscles
- forms longitudinal axis of body
- comprises roughly 40% (80) of bones
skull components
associated bones, cranium, and face
associated bones
7
- 6 auditory ossicles
- hyoid bone
cranium
8
- 1 occipital bone
- 2 parietal bones
- 1 frontal bone
- 2 temporal bones
- 1 sphenoid
- 1 ethmoid
face
14
- 2 maxillae
- 2 palantine
- 2 nasal bones
- 2 inferior nasal conchae
- 2 zygomatic bones
- 2 lacrimal bones
- 1 vomer
- 1 mandible
primary curve
fetal curve, present from time of fetal development
- thoracic
- sacral
secondary curve
curve because of what we do
- cervical because lift head
- lumbar because stand upright
cervical
- secondary cure
- 7 vertebrae
thoracic
- primary curve
- 12 vertebrae
lumbar
- secondary curve
- 5 vertebrae
sacral
- primary curve
- 5 fused vertebrae
coccygeal
3-5 fused vertebrae
kyphosis
normal thoracic curve becomes exaggerated posteriorly, producing a roundback appearance
lordosis
"sway back," both abdomen and butt protrude abnormally
scoliosis
abnormal lateral curvature of the spine; most common distortion of spine
appendicular skeleton
-gives individuals control over environment
- changes body's position in space
- provides mobility
- comprises 60% of bones (126)