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11 Cards in this Set
- Front
- Back
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What is blood?
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It is specialized C.T
-It contains cells and platelets which make up the formed elements -It also has the ECM which is the fluid and the plasma -This contains 90% H20, 1% ions and gases, 0.9% plasma proteins |
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What is present in the formed elements?
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Erythrocytes make out 99.9% of the blood cells
-biconcave which increases SA -packed w/ Hb, which bind to oxygen and Co2 (HCO3- is the major plasma buffer) |
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Properties of RBCs
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-Small, able to squeeze through closed capillaries
-Made by erythropoesis in B. marrow -RBCs lose cytoskeletal fragility with age which targets for its destruction in the spleen |
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What are leukocytes?
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They are white blood cells and they function outside blood (in C tissue)
-Adhere to and migrate through blood vessel walls -via focal adhesions |
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What are granuocytes?
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They are leukocytes and that function in low specificity response
-They have specific granules, secretory vesicles -Neutrophils, basophils, eosinophils |
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Neutrophils
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Very short-lived: Hours in circulation; Days in the Connective Tissues
1st responders during !Innate Immune" response (eg. Inflammation) -Phagocytic when activated and they generate pus when they swell and die |
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Basophils
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Long-lived: 1-2 years in Connective Tissues: Initiate/Amplify Innate Immune Response
•Specific Granules are highly basophilic with histamine (vasodilator) and heparin (anti-coagulant) •Also contain chemoattractants for Neutrophils and Eosinophils -Very few in blood |
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Eosinophils
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Short lived: 1-2 weeks in Connective Tissues; Active in Late Stages of Innate and
Adaptive Immune Responses -Phagocytose neutralized antigen/antibody complexes and destroys them during the end stages of an adaptive immune response |
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What are the types of agranuocytes
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Monocytes, lymphocytes
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Monocytes
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Activated in Connective Tissue To Become Macrophages
- Phagocytic - Operated thoughout Innate Immune Response - Antigen Presenting Cells - Help Initiate the !Adaptive" Immune Response |
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Lymphocytes
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Important in adaptive immunity
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