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96 Cards in this Set

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Secretin

Inhibits gastrin. Enhances the flow of bile rich in HCO3 from the liver.

CCK

Cholecystokinin cause contraction of the gallbladder and increase in digestive enzymes

Common bile duct

Made up of the cystic duct from the gallbladder and the common hepatic duct. Empties into the duodenum.

Hepatic Portal Vein

Brings nutrient rich deoxygenated blood to liver

Hepatic Artery

Brings oxygenated blood to the liver. Branches off of the aorta

Liver's function in carbohydrate metabolism

To breakdown protein and triglycerides into glucose, glucose into glycogen, and glycogen into glucose as needed.

Liver's function in lipid metabolism

Synthesizes cholesterol, lipoproteins (HDL & LDL), stores fat, breaks down fat

Liver's function in protein metabolism

Deamination (to make amino acids usable as energy), converts ammonia to uria, makes plasma proteins (for clotting) converts amino acids into one another.

Gastrin

Digestive hormone of the stomach

Gastric inhibitory peptide (GIP)

Hormone of the stomach which shuts it down and stimulates pancreas to release insulin.

Secretin

Digestive hormone of the pancreas, liver and stomach

Cholecystokinin CCK

Digestive hormone of the pancreas, gallbladder, sphincter of Oddi, and stomach

Three parts of the small intestine

Duodenum, Jejunum, Ileum

GI histology from inside out

Mucosa, Submucosa, Muscularis, Serosa

Structures that increase surface area in the small intestine

Plica circularis


Villi


Microvilli (brush border)

Purpose of Microvilli

To secrete digestive enzymes and absorb nutrients in the small intestine

Paneth Cells

Secrete lysozomes in the small intestine

Brunner's Glands

Secrete alkaline mucus in the small intestine to neutralize stomach acid

Crypts of Lieberkuhn

Secrete lysozomes, intestinal juice, and brush border enzymes

Crypts of Lieberkuhn

Secrete lysozomes, intestinal juice, and brush border enzymes

True or false, peristalsis is stronger in the small intestine than in the stomach

False

What is segmentation

Small "beads" or segments in the small intestine are created to mix chyme with intestinal juice

Chylomicrons

A class of Lipoprotein formed in the intestines. Protein coated fat enters lacteal to be transported to veins -> liver -> out of body

Lacteals

Lymphatic vessel of the small intestine that removes digested fats

Fat soluble vitamin absorption

Broken down and coated in bile salts. Result = Micelle. Then absorbed by diffusion

Water soluble vitamin absorption

Diffusion

B-12 absorption

Combines with intrinsic factor = active transport

Appendicitis

Inflammation of the appendix due to blockage. Symptoms include fever, high WBC, pain in LRQ, vomiting. May lead to peritonitis.

Taenia coli

Outer longitudinal muscle on large intestine

Haustra

Pouches formed by the contraction of the outer longitudinal muscle of the large intestine.

Epiploic appendages

Fat sacs hanging from large intestine

Serosa

Visceral peritoneum

True or false: Appendix has a lot of lymphatic tissue

True

Gastrocolic reflex

Makes us want to poop after we eat to make room.

True or false, there are many enzymes secreted in the large intestine

False. There are none. Only mucus

Why is poop brown?

Bilirubin

Which vitamins do the bacteria in your large intestine produce?

K and B

Sphincter of Oddi

Where the common bile duct and pancreatic duct combine and enter the duodenum

Ampulla of Vater

The combined tube of the CBD and the pancreatic duct

Acini

99% of the pancreatic glandular tissue which forms pancreatic juice

Islets of Langerhans

1% of pancreatic glandular tissue producing hormones

Pancreatic Enzymes

Amylase, lipase, proteases (trypsin), ribonuclease, deoxyribonuclease

Pancreatitis

Inflammation of the pancreas. Extremely painful - pancreas is digesting itself via trypsin


Causes: alcohol, obstruction and diabetes


Treatment: narcotics, and NPO

Sinusoid

Blood filled spaces in between hepatocytes

Kupffer cells

Phagocytes

Bile Canaliculus

Bile collection ducts

Hepatic Triad

Hepatic Artery, Hepatic Portal Vein, bile duct

Gallbladder and Submucosa

It doesn't have one

Catabolism: definition and examples

The breakdown of compounds to provide energy.


Examples: glycolysis, Krebs cycle and electron transport chain

Anabolism

Synthesizes compounds which requires energy (endergonic)

Oxidation

A decrease in the energy of a molecule when it loses an electron or a hydrogen

Reduction

The increase in energy of a molecule when it gains an electron or a hydrogen

Coenzyme: definition and examples

Carries a hydrogen atom from one molecule to another


Examples: NAD, NADP, FAD

Phosphorylation

The addition of a phosphate group to a molecule to add energy


ADP+P = ATP

Phosphorylation in the cytoplasm

Glycolysis

Phosphorylation in the mitochondria

Acetyl CoA, Krebs cycle, Electron transport chain

Glycogenesis

The formation of glycogen from glucose stimulated by insulin

Lipogenesis

The formation of triglycerides

Cellular Respiration

Glucose + O2 = H2O + CO2 + energy used to form 36 to 38 ATP

Is Glycolysis anaerobic or aerobic?

Anaerobic

Aerobic Respiration

Acetyl CoA, Krebs cycle, Electron transport chain

Glycolysis summary

Glucose is broken down to pyruvic acid which is then decarboxylated to form Acetyl CoA so that it can enter the Krebs Cycle. 2 ATP go in, 4 ATP come out.


Where: cytoplasm of mitochondria

Krebs Cycle - what and where

Oxidation reduction and decarboxylation redactions to take Acetyl CoA and produce coenzyme's 3 NADH & 1 FADH2 & 1ATP


Where: matrix of mitochondria

Electron Transport Chain

The oxidation-reduction of membrane proteins to release small amounts of energy


Where: inner membrane of mitochondria

Chemiosmosis

Uses energy released from the ETC to pump H+ from matrix to membrane to produce ATP

What happens when NADH & FADH2 are reduced? And where does this occur?

They release energy. Occurs in the matrix

How many net ATP are produced during glycolysis?

2 ATP

How many net ATP are produced during the Krebs Cycle?

2 ATP

How many net ATP are produced during the Electron Transport Chain?

32 ATP

Glycogenolysis

Converting glycogen to glucose. Stimulated by glucagon

Gluconeogenesis

Formation of glucose from fats or amino acids

4 Classes of Lipoproteins

Chylomicrons, VLDLs, LDL's, HDLs

VLDLs

10% protein. Moves triglycerides formed in the liver to fat cells

LDLs

25% protein. "bad cholesterol". Carries blood cholesterol to body cells

HDLs

40% protein. "Good cholesterol". Picks up cholesterol from blood and returns it to the liver for destruction

Where is body cholesterol synthesized?

The liver

**Albumin

The largest plasma protein used for clotting and immunity. Maintains osmotic pressure. Transports leaked plasma back into the blood stream, otherwise you get the distended African belly.

**All nutrients can be turned into any other EXCEPT...

Essential amino acids and fatty acids

Chief Cells

Secrete inactive pepsinogen which are activated by HCL from Parietal cells

Parietal Cells

Secrete intrinsic factor and HCL to activate pepsinogen from Chief Cells

Where does systemic blood flow in regard to oxygen concentration?

It flows to areas of low oxygen

Where does pulmonary blood flow in regard to oxygen concentration?

To areas of high concentration

What is a P/Q mismatch?

The amount of blood flow is disproportionate to the size of the vessel it is moving through

Do pulmonary veins dilate or constrict in response to low O2?

Constrict

Intubation also know as

Endotracheal intubation

What is the dividing line between the respiratory and digestive systems?

The epiglottis

What type of tissue makes up the glottis?

Elastic cartilage

Vestibular fold

Upper, false vocal chords. Help to close larynx

What are your regular tonsils called?

Palatine tonsils

Nasal passage connects to eustachian tube, why?

To mediate pressure in the middle ear

Infection in the middle ear is known as what? And what always accompanies it?

Otitis media. Accompanied by pharyngitis

What type of tissue makes up the inside of the nose?

Stratified squamous epithelium. Same as your skin

What type of tissue makes up the olfactory plate?

Olfactory epithelium

What type of tissue is the rest of the olfactory system made up of?

Pseudostratified ciliated columnar epithelium with goblet cells (PCCE)

External respiration

Oxygen exchange from the lungs to alveoli

Internal respiration

Gas exchange at the tissue level