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96 Cards in this Set
- Front
- Back
Secretin |
Inhibits gastrin. Enhances the flow of bile rich in HCO3 from the liver. |
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CCK |
Cholecystokinin cause contraction of the gallbladder and increase in digestive enzymes |
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Common bile duct |
Made up of the cystic duct from the gallbladder and the common hepatic duct. Empties into the duodenum. |
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Hepatic Portal Vein |
Brings nutrient rich deoxygenated blood to liver |
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Hepatic Artery |
Brings oxygenated blood to the liver. Branches off of the aorta |
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Liver's function in carbohydrate metabolism |
To breakdown protein and triglycerides into glucose, glucose into glycogen, and glycogen into glucose as needed. |
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Liver's function in lipid metabolism |
Synthesizes cholesterol, lipoproteins (HDL & LDL), stores fat, breaks down fat |
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Liver's function in protein metabolism |
Deamination (to make amino acids usable as energy), converts ammonia to uria, makes plasma proteins (for clotting) converts amino acids into one another. |
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Gastrin |
Digestive hormone of the stomach |
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Gastric inhibitory peptide (GIP) |
Hormone of the stomach which shuts it down and stimulates pancreas to release insulin. |
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Secretin |
Digestive hormone of the pancreas, liver and stomach |
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Cholecystokinin CCK |
Digestive hormone of the pancreas, gallbladder, sphincter of Oddi, and stomach |
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Three parts of the small intestine |
Duodenum, Jejunum, Ileum |
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GI histology from inside out |
Mucosa, Submucosa, Muscularis, Serosa |
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Structures that increase surface area in the small intestine |
Plica circularis Villi Microvilli (brush border) |
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Purpose of Microvilli |
To secrete digestive enzymes and absorb nutrients in the small intestine |
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Paneth Cells |
Secrete lysozomes in the small intestine |
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Brunner's Glands |
Secrete alkaline mucus in the small intestine to neutralize stomach acid |
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Crypts of Lieberkuhn |
Secrete lysozomes, intestinal juice, and brush border enzymes |
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Crypts of Lieberkuhn |
Secrete lysozomes, intestinal juice, and brush border enzymes |
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True or false, peristalsis is stronger in the small intestine than in the stomach |
False |
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What is segmentation |
Small "beads" or segments in the small intestine are created to mix chyme with intestinal juice |
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Chylomicrons |
A class of Lipoprotein formed in the intestines. Protein coated fat enters lacteal to be transported to veins -> liver -> out of body |
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Lacteals |
Lymphatic vessel of the small intestine that removes digested fats |
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Fat soluble vitamin absorption |
Broken down and coated in bile salts. Result = Micelle. Then absorbed by diffusion |
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Water soluble vitamin absorption |
Diffusion |
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B-12 absorption |
Combines with intrinsic factor = active transport |
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Appendicitis |
Inflammation of the appendix due to blockage. Symptoms include fever, high WBC, pain in LRQ, vomiting. May lead to peritonitis. |
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Taenia coli |
Outer longitudinal muscle on large intestine |
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Haustra |
Pouches formed by the contraction of the outer longitudinal muscle of the large intestine. |
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Epiploic appendages |
Fat sacs hanging from large intestine |
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Serosa |
Visceral peritoneum |
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True or false: Appendix has a lot of lymphatic tissue |
True |
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Gastrocolic reflex |
Makes us want to poop after we eat to make room. |
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True or false, there are many enzymes secreted in the large intestine |
False. There are none. Only mucus |
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Why is poop brown? |
Bilirubin |
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Which vitamins do the bacteria in your large intestine produce? |
K and B |
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Sphincter of Oddi |
Where the common bile duct and pancreatic duct combine and enter the duodenum |
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Ampulla of Vater |
The combined tube of the CBD and the pancreatic duct |
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Acini |
99% of the pancreatic glandular tissue which forms pancreatic juice |
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Islets of Langerhans |
1% of pancreatic glandular tissue producing hormones |
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Pancreatic Enzymes |
Amylase, lipase, proteases (trypsin), ribonuclease, deoxyribonuclease |
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Pancreatitis |
Inflammation of the pancreas. Extremely painful - pancreas is digesting itself via trypsin Causes: alcohol, obstruction and diabetes Treatment: narcotics, and NPO |
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Sinusoid |
Blood filled spaces in between hepatocytes |
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Kupffer cells |
Phagocytes |
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Bile Canaliculus |
Bile collection ducts |
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Hepatic Triad |
Hepatic Artery, Hepatic Portal Vein, bile duct |
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Gallbladder and Submucosa |
It doesn't have one |
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Catabolism: definition and examples |
The breakdown of compounds to provide energy. Examples: glycolysis, Krebs cycle and electron transport chain |
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Anabolism |
Synthesizes compounds which requires energy (endergonic) |
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Oxidation |
A decrease in the energy of a molecule when it loses an electron or a hydrogen |
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Reduction |
The increase in energy of a molecule when it gains an electron or a hydrogen |
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Coenzyme: definition and examples |
Carries a hydrogen atom from one molecule to another Examples: NAD, NADP, FAD |
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Phosphorylation |
The addition of a phosphate group to a molecule to add energy ADP+P = ATP |
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Phosphorylation in the cytoplasm |
Glycolysis |
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Phosphorylation in the mitochondria |
Acetyl CoA, Krebs cycle, Electron transport chain |
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Glycogenesis |
The formation of glycogen from glucose stimulated by insulin |
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Lipogenesis |
The formation of triglycerides |
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Cellular Respiration |
Glucose + O2 = H2O + CO2 + energy used to form 36 to 38 ATP |
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Is Glycolysis anaerobic or aerobic? |
Anaerobic |
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Aerobic Respiration |
Acetyl CoA, Krebs cycle, Electron transport chain |
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Glycolysis summary |
Glucose is broken down to pyruvic acid which is then decarboxylated to form Acetyl CoA so that it can enter the Krebs Cycle. 2 ATP go in, 4 ATP come out. Where: cytoplasm of mitochondria |
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Krebs Cycle - what and where |
Oxidation reduction and decarboxylation redactions to take Acetyl CoA and produce coenzyme's 3 NADH & 1 FADH2 & 1ATP Where: matrix of mitochondria |
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Electron Transport Chain |
The oxidation-reduction of membrane proteins to release small amounts of energy Where: inner membrane of mitochondria |
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Chemiosmosis |
Uses energy released from the ETC to pump H+ from matrix to membrane to produce ATP |
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What happens when NADH & FADH2 are reduced? And where does this occur? |
They release energy. Occurs in the matrix |
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How many net ATP are produced during glycolysis? |
2 ATP |
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How many net ATP are produced during the Krebs Cycle? |
2 ATP |
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How many net ATP are produced during the Electron Transport Chain? |
32 ATP |
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Glycogenolysis |
Converting glycogen to glucose. Stimulated by glucagon |
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Gluconeogenesis |
Formation of glucose from fats or amino acids |
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4 Classes of Lipoproteins |
Chylomicrons, VLDLs, LDL's, HDLs |
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VLDLs |
10% protein. Moves triglycerides formed in the liver to fat cells |
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LDLs |
25% protein. "bad cholesterol". Carries blood cholesterol to body cells |
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HDLs |
40% protein. "Good cholesterol". Picks up cholesterol from blood and returns it to the liver for destruction |
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Where is body cholesterol synthesized? |
The liver |
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**Albumin |
The largest plasma protein used for clotting and immunity. Maintains osmotic pressure. Transports leaked plasma back into the blood stream, otherwise you get the distended African belly. |
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**All nutrients can be turned into any other EXCEPT... |
Essential amino acids and fatty acids |
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Chief Cells |
Secrete inactive pepsinogen which are activated by HCL from Parietal cells |
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Parietal Cells |
Secrete intrinsic factor and HCL to activate pepsinogen from Chief Cells |
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Where does systemic blood flow in regard to oxygen concentration? |
It flows to areas of low oxygen |
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Where does pulmonary blood flow in regard to oxygen concentration? |
To areas of high concentration |
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What is a P/Q mismatch? |
The amount of blood flow is disproportionate to the size of the vessel it is moving through |
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Do pulmonary veins dilate or constrict in response to low O2? |
Constrict |
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Intubation also know as |
Endotracheal intubation |
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What is the dividing line between the respiratory and digestive systems? |
The epiglottis |
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What type of tissue makes up the glottis? |
Elastic cartilage |
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Vestibular fold |
Upper, false vocal chords. Help to close larynx |
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What are your regular tonsils called? |
Palatine tonsils |
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Nasal passage connects to eustachian tube, why? |
To mediate pressure in the middle ear |
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Infection in the middle ear is known as what? And what always accompanies it? |
Otitis media. Accompanied by pharyngitis |
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What type of tissue makes up the inside of the nose? |
Stratified squamous epithelium. Same as your skin |
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What type of tissue makes up the olfactory plate? |
Olfactory epithelium |
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What type of tissue is the rest of the olfactory system made up of? |
Pseudostratified ciliated columnar epithelium with goblet cells (PCCE) |
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External respiration |
Oxygen exchange from the lungs to alveoli |
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Internal respiration |
Gas exchange at the tissue level |