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71 Cards in this Set

  • Front
  • Back
sagittal plane

(and alternative name)
anteroposterior
Frontal plane

(alternative name?)
coronal plane
transverse plane

(alternative name?)
horizontal plane
internal-external
nearer to -or- farther from the center
Rostral
used in describing the brain

nearer anterior part of head
caudal- cranial
toward tail region -or- toward the head
unilateral- bilateral
occuring on one side -or- having right and left members
circumduction
distal end circular movement
rotation
revolving around longitudinal axis
medial/ internal rotation
brings anterior surface closer to median plane
eversion- inversion
movement of sole away from median plane -or- movement of sole toward median plane
reposition
movement from opposition back to anatomical position
retrusion
opposite of protrusion

movement backward of chin/lips/tongue
integumentary functions
protection
excretion
regulate body temp
produce vitamin D
storage lipids in adipocytes
extend range of nervous system
layers of integumentary
Epidermis, Dermis, subcutaneous tissue (superficial fascia-- not really part of skin)
Epidermis
-keratinized epithelium
-tough, protective outer layer over regenerative, pigmented basal layer
-no blood vessels or lymphatics
keratin cells in epidermis
are horny like substances made of proteins
stratum germinativum (aka stratum basale)
-single row of rapidly dividing stem cells
-hemidesmosomes attach it to underlying dermis
-epidermal ridges increase surface connection with dermis
-basal cell carcinoma originates in stem cells of this layer.
hemidesmosomes
attach one cell to the extracellular matrix

attach stratum germinativum to underlying dermis.
integumentary functions
protection
excretion
regulate body temp
produce vitamin D
storage lipids in adipocytes
extend range of nervous system
layers of integumentary
Epidermis, Dermis, subcutaneous tissue (superficial fascia-- not really part of skin)
Epidermis
-keratinized epithelium
-tough, protective outer layer over regenerative, pigmented basal layer
-no blood vessels or lymphatics
keratin cells in epidermis
are horny like substances made of proteins
stratum germinativum (stratum basale)
-single row of rapidly dividing stem cells
-hemidesmosomes attach it to underlying dermis
-epidermal ridges increase surface connection with dermis
-basal cell carcinoma originates in stem cells of this layer
5 epidermal layers- starting superficial
1. stratum corneum
2. stratum lucidum
3. stratum granulosum
4. stratum spinosum
5. stratum germinativum
basal cell carcinoma
-type of non-melonoma skin cancer
-most common cancer in US
-accounds for 75% of skin cancer
-rarely metastasizes
-occurs on skin regularly exposed to sun/ UV radiation
-appears as flat lesions
hemidesmosomes
attach one cell to the extracellular matrix

attach stratum germinativum to underlying dermis
stratum spinosum
-8-10 cells thick
-langerhans' cells
-keratinocytes continue to divide
-squamous cell carcinoma originates in keratinocytes here
Langerhans' cells
take up and process microbial antigens during skin infections
squamous cell carcinoma
-2nd most common
-appears crusted/ scaly patches w/ red, inflamed base or growing tumor
-slow-growing malignant tumor
-frequently found in lungs and skin (also occuring in anus, cervix, larynx, nose, and bladder)
Melanoma
-malignant tumor of melanocytes (cells that produce pigment melanin)
-predominantly in skin
-less common--more deadly
(75% deaths related to skin cancer)
stratum granulosum
-3-5 cells thick
-cells become flattened
-cells produce toughening keratin and keratohyaline granules
stratum lucidum
-very thin layer
-found only in thick skin
-densely packed with keratin
stratum corneum
-15-30 cells thick
-cells dead
-accounts for 3/4 of epidermal thickness
-cells very tough and water resistant
dermis
-vascularized/contains nerve endings
-dense, interlacing collagen and elastic fibers
-provides skin tone/ strength and toughness
-fiber direction provides tension lines (langer lines)
langer lines
tension lines in skin

in cuts, if you cut along a langer line the wound will close up nice. if you cut across, the would will gap
dermal layers
papillary layer

reticular layer
papillary layer
-areolar connective tissue
-collagen/elastin fibers form loose mat
-abundant blood vessels, nerve fibers, lymphatic vessels
-superior surface forms dermal papillae
areolar connective tissue
connective tissue, loosely organized
reticular layer
-80% dermal thickness
-primarily dense irregular connective tissue
-collagen/elastin fibers extend up into papillary layer and down into subcutaneous layer
dermal papillae
form fingerprints

form superficial layer of dermis--protrude into epidermal layer
erythema
unusually red

heat, inflammation, allergic reactions-- superficial capillary bedsengorged
stretch marks
rapid changes stretch skin "too much" damaging collagen fibers in dermis

deep fascia is loosened due to protein breakdown--leading to reduced cohesion btw collagen fibers
fascia
layer or boundar in body

fascia suround all our muscles, etc...
1st degree burn
limited to epidermis

cells quickly replaced from basal layer
2nd degree burn
epidermis and superficial dermis
-nerve endings damaged, hair follicle or sweat glands provide replacement cells for basal layer
3rd degree burn
entire thickness and possible underlying muscle

marked edema--are numb because sensory endings destroyed
topical medications/ ointments
drug administered to skin or mucous membrane

lipid-soluble more readily absorbed
transdermal patches
attach to skin by adhesive layers

may be mixed with oily base to increase solubility

provide slow, controlled release to ensure constant plasma level of drug
functions of skeletal system
-support
-protection
-leverage necessry for movement
-mineral and lipid storage
-blood cell production
short bones
roughly cube shaped
sesamoid bones
form within tendons and frequently alter the direction of muscle pull. variable

ex patella
sutural bones
(wormian bones)

small flattened bones in skull. variable
bone composition
-calcium carbonate and calcium phosphate (60-70% dry weight; provides rigidity, compressive strength)

-collagen protein (provides flexibility, tensile strength)

-water (25-30% weight, contributes to strength)
compact bone (cortical bone)
external part of bone

looks smooth and solid to naked eye
spongy bone (trabecular bone)
(cancellous bone)

-internal part of bone
-honeycomb of osseous
-tissue called trabeculae
filled with bone marrow

has vertical and horizontal columns that resist force
diaphysis
-shaft of LONG bone
-compact bone externally
-central medullary cavity contains bone marrow
epiphyses
-end of LONG bone, larger diameter than diaphysis
-compact bone externally
-spongy bone internally
structure of flat bone
-layer of spongy bone btw compact bone (dipole)
-spongy bone contains bone marrow, althogh no marrow cavity is present
periosteum
-covers outer surface of bone except joint surface
-outer layer dense irregular connective tissue
-inner layer composed primarily of osteoprogenitor cells along with osteoblasts and osteoclasts
-richly supplied with blood vessels, nerve fibers, lymphatic vessels
-continuous with joint capsules, tendons, ligaments
endosteum
-covers trabeculae of spongy bone and lines canals that pass through compact bone
-composed of osteoprogenitor cells with osteoblasts and osteoclasts
-lacks dense irregular connective tissue present in periosteum
osteoprogenitor cells
becomes osteoblast and osteoclast
osteogenesis (ossification)
process of bone tissue formation

-in embryos--leads to development of body skeleton
-before adulthood--leads to growth of skeleton
-in adulthood--leads to increase in thickness of bones--remodeling and repair of bones
embryonic development of bone--two different tissue types bone develops from
1. fibrous CT
-intramembranous ossification (leads to formation of most bones in skull and miscellaneous other bone)

2. hyaline cartilage
-endochondral ossification (bones of skeleton from base of skull down (some exceptions)
osteoclasts
of endosteum and spongy bone/ compact bone interface remove internal bone (keeps bones light)
bone growth in length
extension of endochondral ossification (i.e. cartilage forms and is replaced by bone)
adult bone
increasing loss of collagen

age-related decline in density

trabecular bone affected
Type 1 osteoporosis
post menopausal osteoporosis

40% women over 50
Type II osteoporosis
age associated osteoporosis
-affects most women
-men after age 70
-90% of all fractures after age 60 related to osteoporosis
dowager's hump-- cause
crush fractures of trabecular bone in vertebrae
fibrous joints
connected by fibrous tissue

1. syndemosis type-- partially moveable- connected by sheet of ligament of fibrous membrane
2. gomphosis type- peg-like process and socket