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54 Cards in this Set

  • Front
  • Back
Perfusion limited
The transfer of gas across the alveolar wall is a function of the amount of blood that flows past the alveoli.
Diffusion limited
Means that the movement of gas across the alveolar wall is a function of the integrity of the alveolar-capillary membrane itself.
Oxygen toxicity affects
The lung and central nervous system.
Solubility Coefficient
The amount of gas that can be dissolve by 1mL of a given liquid at standard(760 mmhg) and specified temperature
Flicks law
States that rate of gas transfer across a sheet of tissue is directly proportional to the surface area of the tissue. Directly proportional to the diffusion Constants. Directly proportional to the difference in partial pressure of the gas between the two sides of the tissue. It is inversely proportional to the thickness of the tissue.
Henry's law
The amount of gas that dissolves in a liquid at a given temperature is proportional to the partial pressure of gas
CO2 is 24 times more soluble than O2
What is the normal capacity of CO
25 mL/min/mmHg
Dalton law
Law of partial pressure
Percentage of PN2 (partial pressure nitrogen)
78.08%
% of PO2 (partial pressure oxygen)
21%
% of PCO2 (partial pressure of carbon dioxide)
.03%
% of other partial pressure in the air
93%
Formula for ideal alveolar gas equation
PAo2= [Pb-Ph20] FIo2 - Paco2 (1.25)
Graham's law
Rate of diffusion of gas through liquid is 1. directly proportional to the solubility of coefficient of the gas number 2. indirectly proportional to the square root of the grand molecule or weight


Graham and Henry law states that
Carbon dioxide diffuses 20X faster than oxygen
Rate of diffusion of two gases is proportional to ratio of their solubility coefficient and inversely proportional to ratio of their gram molecule and weight
What does the A component in Flicks law verify?
verified that a decreased alveolar surface area decreases the ability of oxygen to enter the pulmonary capillary blood
What does the P1-P2 in flicks law verify?
It confirm that a decreased alveolar oxygen pressure(PAo2 or P1), cause by high altitude or alveolar hypoventilation, reduces the diffusion of oxygen into the pulmonary capillary blood
What does the T factor in flicks law verify?
Is confirmed in that an increase in alveolar tissue thickness (caused by alveolar fibrosis or Alveolar edema) reduces the movement of oxygen across alveolar capillary membrane
Disorders that cause alveolar capillary membrane thickness to increase
Pulmonary edema, pneumonia, interstitial lung disease, acute respiratory distress syndrome (ARDS) respiratory distress syndrome(RDS) in newborn
Hyperbaric oxygen therapy (HBOT)
Therapeutic application of oxygen pressures greater than 1 atm.
Gas diffusion
The movement of individual gas (N2, O2, CO2) molecules from an area of high pressure (high concentration) to an area of low pressure (low concentration)
Diffusion gradient
Individual gas partial pressure differences
Henry's law
The amount of gas that dissolves in a liquid at a given temperature is proportional to the partial pressure of gas
CO2 is 24 times more soluble than O2
What is the normal capacity of CO
25 mL/min/mmHg
Dalton law
Law of partial pressure
Percentage of PN2 (partial pressure nitrogen)
78.08%
% of PO2 (partial pressure oxygen)
21%
% of PCO2 (partial pressure of carbon dioxide)
.03%
% of other partial pressure in the air
93%
Formula for ideal alveolar gas equation
PAo2= [Pb-Ph20] FIo2 - Paco2 (1.25)
Water vapor
Water in the gaseous form, when in volume of gas it exerts a partial pressure
Graham's law
Rate of diffusion of gas through liquid is 1. directly proportional to the solubility of coefficient of the gas number 2. indirectly proportional to the square root of the grand molecule or weight


Graham and Henry law states that
Carbon dioxide diffuses 20X faster than oxygen
Rate of diffusion of two gases is proportional to ratio of their solubility coefficient and inversely proportional to ratio of their gram molecule and weight
What does the A component in Flicks law verify?
verified that a decreased alveolar surface area decreases the ability of oxygen to enter the pulmonary capillary blood
What does the P1-P2 in flicks law verify?
It confirm that a decreased alveolar oxygen pressure(PAo2 or P1), cause by high altitude or alveolar hypoventilation, reduces the diffusion of oxygen into the pulmonary capillary blood
What does the T factor in flicks law verify?
Is confirmed in that an increase in alveolar tissue thickness (caused by alveolar fibrosis or Alveolar edema) reduces the movement of oxygen across alveolar capillary membrane
Disorders that cause alveolar capillary membrane thickness to increase
Pulmonary edema, pneumonia, interstitial lung disease, acute respiratory distress syndrome (ARDS) respiratory distress syndrome(RDS) in newborn
Hyperbaric oxygen therapy (HBOT)
Therapeutic application of oxygen pressures greater than 1 atm.
Gas diffusion
The movement of individual gas (N2, O2, CO2) molecules from an area of high pressure (high concentration) to an area of low pressure (low concentration)
Diffusion gradient
Individual gas partial pressure differences
Alveolar gas has how much absolute humidity / water vapor pressure?
47mg/L.
47 torr
Pv02
40 torr
Pv02
40 torr
Pv CO2
46 torr
Pv02
40 torr
Pv CO2
46 torr
PA o2
100 torr
Pv02
40 torr
Pv CO2
46 torr
PA o2
100 torr
PA co2
40 torr
What happens to time/rate during diffusion when excercising?
Increase rate decrease time
What is the disease that decrease rate n time of diffusion
Pulmonary edema
Pneumonia
Interstitial lung disease
How to fix decrease rate n time in diffusion
Treatment increase patient oxygen