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39 Cards in this Set
- Front
- Back
List 3 types of muscle tissue
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skeletal,cardiac and smooth
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Describe the difference between the point of origin and the point of insertion
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The point which moves the least is the origin
The point that moves the most is the insertion |
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There are 3 components which comprise the internal structure of a muscle. What are they?
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The epimysium, the perimysium and the endomysium
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Where is epimysium located?
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.Epimysium covers the entire muscle
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What is the function of the perimysium?
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.Perimysium controls fascile (little bundle). It is what we actually use
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What function does endomysium serve and why is it important?
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Endomysium separate and electrically insulates muscle cells from each other. Therefore you have control over individual muscle
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Why is Compartment syndrome detrimental to muscle function?.
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.If a muscle is traumatized fluid can pool in the area. Swelling blocks muscle function
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List a few organelles found in skeletal muscle cells
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A.Nucleus
B.Sarcoplasmic reticulum C.Sarcoplasmic D.Terminal Cisternae |
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Describe terminal cisternae
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Resevoirs for calcium
vomit calcium, calcium then interact with portion of muscle fiber |
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What is a T-tubule?
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a transverse tubule extends into the sarcomplasmic as invaginations contiuous with the sarcolemma
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define myofibril
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cylindrical bundle of contractile filaments within the cell
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Myofibrils are comprised of myofilaments. Describe their composition
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2 types of myofilament
Actin -thin filament .Myosine- thick filament |
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Test question: One Z line to the next is called a
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sarcomere -functional unit of muscle contraction
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List and describe the organizational Levels of skeletal muscle
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(a)Myofilaments thick and thin
(b)myofibril many myofilaments (c)muscle cell (d)Fascile (e)whole skeletal muscles |
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The site where an axon and a muscle fiber meet is called a
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Neuromuscular Junction
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What is the Neuromuscular Junction? What does the Neuromuscular Junction control?
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It.controls contraction of the muscle produced in nerve cell body
and it is the place where the terminal portion of a motor neuron axon meets the muscle cell membrane |
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The muscle fiber membrane is the specialized area called the
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Motor End Plate
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Describe the role of the Motor Neuron
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In order for the skeletal muscle cells to contract each cell must be stimulated by a process of a motor neuron. Each motor neuron is a single nerve cell extending from the brain or spinal cord to the muscle, where it can stimulate several muscle cells.
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The elongated process of the nerve cell that carries impulses to the muscle is?
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The Axon
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The level of innervation within a muscle is dependent on which 2 factors
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Depends partially from from use and partially from genetics
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The swollen distal end of a motor neuron axon is called the
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Axon Terminal
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What is located within the Axon Terminal?
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i.within the axon terminal are synaptic vesicles containing the neurotransmitter ACh
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Define the Synaptic Cleft
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space between the axon terminal and the folded region of the sarcolemma called the motor end plate
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Little blisters filled with neurotransmitter
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Synaptic Vesicles
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Sarcolemma
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general name for the muscle cell membrane
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Exocytosis
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process by which Acetylcholine is released from the synaptic vesicles
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After exocytosis, what does the ACh accomplish?
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Binds to receptor sites of chemically regulated in channels in the motor end plate
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After de-polarization, where does ACh go?
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ACh will diffuse away from receptor, the channels will close and then you have ACh-ase destroy the ACh
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What causes the terminal cisternae to release calcium ions into the cytosal?
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The action potential
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Calcium Ions serve what function?
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They initiate the contraction of the muscle cell
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Describe the prominent, current theory of muscle contraction.
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Sliding Muscle Theory. Theory that states when sarcomeres shorten, the thick and thin filaments do not change in length (the filaments slide over each other)
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5 Molecules Contribute to the sliding muscle theory. What are they?
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myosin actin, tropomyosin, troponin, ATP, calcium ions
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Functions and specifics of a molecule
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-.Myosin- are bundled together to form thick filament
-.Molecule looks like golf club with 2 head -.head (cross bridge has ability to move back and forth. ) -hinge portion of linear tail allows vertical movement, &power stroke of cross bridges |
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Thin filaments are comprised of which 3 molecules
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actin, tropomyosin, and troponin
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What are some features of actin?
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Actin is the major component of thin filament. The actin portion of the thin filament is composed of actin subunits twisted into a double helical(helical shape important because it twists. ) chain which has a specific binding site (where myosin wants to attach to)
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Tropomyosin
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regulatory protein which is also a part of the thin filamen. Entwines around the actin &prevents myosin cross-bridge binding
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Troponin
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moves the tropomyosin aside so that actin and myosin can bind Responds to calcium. Attaches. This enables the tropomyosin aside to expose the binding site
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What else does troponin need in order to move tropomyosin away from the binding sites?
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Troponin by itself is not able to move tropomyosin away from the binding site. This process needs calcium ions. After Action potential, calcium ions are released from terminal cisterne and bind to troponin. This drags the tropomyosin off of the binding sites.
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flexion of the cross bridge is called the
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power stroke (test)
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