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15 Cards in this Set

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What medications are commonly associated with Type 1 hypersensitivity reactions?
1)penicillin
2)aspirin
3)lidocaine and anesthetics
4)nitrates
5)MSG
What medications are commonly associated with Type 2 hypersensitivity reactions?
1)methyldopa
2)penicllin
3)sulfas
4)quinidine
What medications are commonly associated with Type 3 hypersensitivity reactions?
1)antivenoms
2)penicillin
3)sulfas
4)phenytoin
What medications are common antigens in anaphylactoid reactions?
1)opiates
2)contrast dyes
3)vancomycin
4)amphotericin
Treatment for a patient with an anaphylactoid reaction
1)recumbent position/elevate extremities
2)tourniquet
3)epinephrine
4)oxygen
5)NS
6)dopamine/NE/
cimetidine/ranitidine
7)nebulized beta-agonist/IV aminophylline
8)solumedrol/hydrocortisone sodium succinate
9)diphenhydramine
10)glucagon
Strength of epipen vs epipen Jr.
Epipen= 1:1000 strenght and delivers 0.3mg in 0.3mls

Epipen Jr= 1:2000 strenght and delivers 0.15mg in 0.3ml (may be appropriate for patients under 30kgs)
Epipen dosing in adults and Epipen Jr dosing in children
1)0.3-0.5mg of 1:1000 strength IM in adults
2)0.15 or 0.3mg SQ or IM in children
Where is epinephrine administered?
1)nonoccluded site
Where is aqueous epinephrine administered?
into site of antigen injection
Dosing for aqueous epinephrine in adults and children
1)0.15-.025ml SQ in adults
2)0.005ml/kg SQ in children
What agents can be used for refractory hypotension to fluid bolus, dopamine, or NE?
1)cimetidine IV
2)ranitidine IV
What is the purpose of corticosteroids?
To block the late phase reaction
How long till improvement seen with corticosteroids?
6-8hours
Diphenhydramine role and IV infusion
1)blocks further histamine release
2)Give IV infusion slowly or you may worsen hypotension
When is glucagon indicated?
1)epinephrine-resitant patients on beta-blockers
2)other options= atropine or isoproterenol