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6 Cards in this Set
- Front
- Back
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agents examples
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methylphendidate, cathinone, ephedrine, etc.
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pharmacological CNS effects
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1)enhanced confidence
2)rebound effects 3)tolerance and dependence 4)amphetamine PSYCHOSIS 5)suppression of appetite (tolerance develops) |
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pharmacological peripheral effects
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1)autonomic-HTN, tachycardia, arrhythmias, mydriasis
2)malnutrition |
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toxicity
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1)sympathomimetic effects
2)CNS-hostility, aggression, psychotic rxns, tactile hallucinations 3)irreversible degenration of dopaminergic and serotenergic pathways |
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MOA
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1)acute effect-enhanced release and inhibition of uptake of NE and DA
2)chronic effect-decreased levels of DA in reward centers of brain 3)direct stimulation of alpha receptors |
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Enhanced excretion can be done how?
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acidifying urine
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