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6 Cards in this Set

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agents examples
methylphendidate, cathinone, ephedrine, etc.
pharmacological CNS effects
1)enhanced confidence
2)rebound effects
3)tolerance and dependence
4)amphetamine PSYCHOSIS
5)suppression of appetite (tolerance develops)
pharmacological peripheral effects
1)autonomic-HTN, tachycardia, arrhythmias, mydriasis
2)malnutrition
toxicity
1)sympathomimetic effects
2)CNS-hostility, aggression, psychotic rxns, tactile hallucinations
3)irreversible degenration of dopaminergic and serotenergic pathways
MOA
1)acute effect-enhanced release and inhibition of uptake of NE and DA
2)chronic effect-decreased levels of DA in reward centers of brain
3)direct stimulation of alpha receptors
Enhanced excretion can be done how?
acidifying urine