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6 Cards in this Set
- Front
- Back
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aminoglycosides
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bactericidal
post antibiotic effect: stays for hrs after levels below MBC *gentamycin |
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uses
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mgmt of serious aerobic g-
NOT for anaerobes |
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absorption
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not to CNS; poor oral abs.
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adverse effects
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nephrotoxicity
ototoxicity neuromusc. block |
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dosing
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watch serum blood levels
depends on... body fat, age, pathophys (kidney prob?), fever, edema, dyhydration... narrow therapeutic margin - use peak and trough combo w/ PCNs |
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agents r/t gentamycin
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tobramycin
neomycin - HIGHEST risk of ototox.; not IV amikacin - broadest spec; least vulnerable to break down |
