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25 Cards in this Set

  • Front
  • Back
(His)
Histidine
-charged
- basic
-side chain may be positive or have no charge within physiological pH
(Gly)
Glycine
-smallest amino acid
-neutral
-aliphatic
-non-polar
(Ala)
Alanine
-aliphatic
-neutral
-non-polar
(Val)
Valine
-neutral
-nonpolar
-aliphatic
(Pro)
Proline
-aliphatic
branched
-non-polar
-neutral
-side chain is bound to amine group
(Leu)
Leucine
-aliphatic
-neutral
-non-polar
Neutral Amino Acids
being neutral means that the amino acid has no charge at physiological pH
(Ile)
Isoleucine
-aliphatic
-neutral
-non-polar
(Phe)
Phenylalanine
-aromatic
-neutral
(Tyr)
Tyrosine
-aromatic
-neutral
-OH gives slight polarity to R group
(Trp)
Tryptophan
-aromatic
-neutral
(Ser)
Serine
-Polar
-nuetral
-hydroxyl makes it polar
(Thr)
Threonine
-polar
-neutral
-contains -OH group
(Cys)
Cysteine
-sulfur containing
-neutral
(Met)
Methionine
-sulfur containing
-neutral
(Asn)
Asparagine
-polar
-contain amide in R group
-neutral
(Asp)
Aspartic acid
-polar
-acidic
(Glu)
Glutamic acid
-acidic
-polar
Acidic Amino Acids
-Aspartic Acid & Glutamic Acid
-have carboxyl group @ end of side chain
-Ionization of -COOH group is pH dependent
at physiological pH the group is negatively charged
(Lys)
Lysine
-charged
-basic
-polar
(Arg)
Arginine
-basic
-polar
Basic Amino Acids
Basic amino acids have nitrogen bases as part of the side chains
Ionization of these groups is pH dependent
At physiological pH Lysine & Arginine side chains are positively charged: pI>9
Histidine side chain may be positive or have no charge @ physiological pH 6<pI<9
Isoelectric point
pH at which there is NO net charge on the molecule
Ranges of pI
pI's for acidic amino acids would be in acidic pH range
pI's for basic amino acids would be in alkaline pH range
pI's for neutral amino acids are in neutral range 5<pI<7
Histidine
histidine side chains contribute to the buffering capacity of certain proteins in the body such as hemoglobin.