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12 Cards in this Set

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Type of bacteria vibrio cholerae

Gram negative toxin producing which causes secretory diarrhoa

Signs and symptoms

Abdominal pain, diarrhea, vomiting fever

Transmission

Ingestion of contaminated water, person to person (10^10-10^12) bacterium shedded in stool


Sharing soap


Eating rice and rice products


O blood group have severe infections


Incubation

Depends on host and inoculum amount


2-3 days to 5-6 days

Clinical manifestations

Fever, diarrhea, abdominal pain and kussmaul breathing, electrolytes imbalance- lethargy and fatigue. Metabolic acidosis, dehydration - sunken eyes, dry mucosa, washer womens hands

Risk factors

Hypochrondynia,

Diarrhea features

Cholera gravis is severe form of diarrhoea


Classical rice water with flecks of mucus


Ok

Investigation

Hypokalemia, hyponatremia, metabolic acidosis, AKI- Acute tubular necrosis, hypocalcemia, hypoglycemia

Complications

Children- aspiration pneumonia


Adults- cholera sicca- fluid accumulation in intestinal lumen, circulatory collapse and death can occur


Diagnostic test

1. Stool culture


2. Raid test - antigen, molecular test and dark field microscopy

Treatment

1. Fluid hydration


2. Antibiotics - fluoroquilones, macrolides, tetracycline


3. Nutrition and vitamin zinc and vitamin A


Prevention

1. Vaccination


2. Breastfeeding


3. Poor food and water safety