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16 Cards in this Set
- Front
- Back
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What is the frequency of erectile dysfunction in men of given ages?
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40% in 40yr olds
70% in 70 yr olds |
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How can you distinguish psychological vs organic ED?
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In psychological ED, pts have normal nocturnal penile tumescence
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What are the 3 major classes of organic causes of ED?
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-Endocrine/hormonal
-Vascular -Neurologic |
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What are 2 mechanisms by which Diabetes mellitus can cause ED?
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-Vascular
-Neurologic |
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What 4 lab tests should you obtain when assessing ED?
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-TSH (thyroid!)
-Fasting sugar -Testosterone -Prolactin |
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What is the go-to drug category used for treating ED?
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PDE-5a inhibitors
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What is the mechanism of PDE-5a inhibitors?
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Inhibit cGMP-specific phosphodiesterase 5a allows the corpora cavernosa smooth muscle to relax
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3 main side effects of PDE-5a inhibitors:
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-flushing
-headache -lower BP |
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What 2 patients can NOT get PDE-5a inhibitors like viagra?
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Those on
-nitrates -alpha blockers |
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What is the injectable form of PDE-5a inhibitor?
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Alprostadil
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2 main drug types for BPH:
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-alpha blockers (terazosin)
-5a-reductase inhibitors (finasteride) |
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What 3 drugs should be AVOIDED in pts with BPH?
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-Narcotics
-Antihistamines -Anticholinergics |
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When can surgical therapy for BPH be performed via:
-TURP -Open |
TURP if <75g prostate
Open if larger |
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What are the guidelines for prostate cancer SCREENING?
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Controversial
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What should you do if an abnormality is appreciated on clinical prostate exam?
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Proceed to BIOPSY
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What is the only use of the PSA?
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To follow response to prostate cancer treatment
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