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21 Cards in this Set

  • Front
  • Back
Chronic cough: 4 way differential
asthma
COPD / chronic bronchitis

post nasal drip
GERD
The absence of wheezing makes ? very unlikely.
asthma
What test and test value is diagnostic for asthma?
lowered FEV1 / FVC
normal is > 75%

see if function is improved with bronchdilator
Definition of asthma?
episodic, REVERSIBLE airway constriction
clinical difference between mild intermittent and mild persistent asthma
mild intermittent: no more than 2 times per week, symptoms not present between episodes

mild persistent: > 2 times per week, but less than 1 time per day.
Night symptoms > 2 times per month.

Symptoms severe enough to interfere in daily activities.
Differentiate between mild persistent and moderate persistent asthma.
mild persistent: > 2 times per week, but less than 1 time per day.
Night symptoms > 2 times per month.
Lung function normal between episodes (>80% expected value)

moderate persistent: > 2 times per week
Night symptoms > 1 time per week.
Lung function tests abnormal between episodes (60-80% of expected value).
What are the parameters of severe persistent asthma?
occurs throughout day,
lung function tests < 60% expected between episodes.
Tx for mild intermittent asthma?
prn albuterol
Tx for asthma above mild intermittent?
(first line)
inhaled corticosteroids
Tx for status asthmaticus?
oxygen
continuous inhaled B agonist
continuous inhaled anticholinergic

IV corticosteroids
ICU monitoring
possible intubation and mechanical ventilation
Name two principal SHORT ACTING B-agonists used to treat asthma and COPD.
albuterol
pirbuterol
Name two principal LONG ACTING B-agonists used to treat asthma and COPD.
salmeterol
formoterol
Name two principal anticholinergics used to treat asthma and COPD.
ipratropium (short acting, stage 1)
tiotropium (long acting, stage 2)
initial presenting sx of COPD
cough, dyspnea
By the time dyspnea develops in COPD, FEV1 has been reduced by ?

How long has COPD been present by the time dyspnea appears?
one half

several years
CXR of moderate COPD will likely show?

More severe COPD will show ?
nothing -- normal xray

hyperinflation, increased PA diameter, flattening of diaphragms
What is the FEV1 / FVC ratio in COPD?
< 0.70
What are the definitions of the four stages of COPD?
They are defined by declining FEV1.
Stage 1 (mild): FEV1 > 80% of predicted
Stage 2 (moderate): FEV1 50-80% of predicted
Stage 3 (severe): 30-50% of predicted
Stage 4: (very severe): <30% of predicted, or <50% of predicted with chronic hypoxemia
tx for stage 1 COPD

tx for stage 2 COPD
short acting bronchodilator (albuterol, ipratropium)

long acting bronchodilator (salmetrol, tiotropium, i
tx for stage 3 and 4 COPD
add inhaled steroids for exacerbations, but long term steroid tx is not recommended

stage IV with hypoxemia (PaO2 < 55*, or pulseox < 88%): oxygen therapy

* <60 with pulmonary htn, PCV, or heart failure with peripheral edema
tx for acute exacerbation of COPD
1. short acting bronchodilators; can combine b-agonist and anticholinergic
2. systemic steroids, which shorten exacerbation course; prednisone 40 for 10-14 days is common.