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32 Cards in this Set
- Front
- Back
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The ? response is a complex concert of reactions to injury
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inlfammatory
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The second line of defenses, are ? immune reactions and this includes ? (CIPI)
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nonspecific
Complement Inflammation Phagocytosis Interferon |
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The 5 classic symptoms of inflammation are ?(redness),?(heat),?(swelling/edema),?(pain),?
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rubor
calor tumor dolor loss of function |
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? are another component of nonspecific immunity and they can be exogenous or endogenous
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pyrogens
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? increases the rapidity of the host immune responses and reduces the viability of many microbial invaders
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Fever
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Macrophages are activated ? Along with PMN's(neutrophils) they are the key ? agents of nonspecific response to disease.
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monocytes
phagocytic |
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The plasma contains ?, a nonspecific group of chemicals that works on its own or with the 3rd line of defense to attack foreign cells
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complement
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What are the chief functions of inflammation?
A.? B.? C.? |
A. Mobilize & attract immune components to the site of injury
B. Set in motion mechanisms to repair tissue damage, localize & clear harmful substances. C. Destroy microbes and block further invasion |
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When the inflammatory response is chronic, it has the potential to actually cause ?, ?, and ?
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tissue damage
disease destruction |
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The stages of inflammation in order are ?,?,?,?, and ?
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injury
rubor & calor tumor/ loss of function dolor |
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A small protein released by cells that has a specific effect on the interactions between cells, on communications between cells or on the behavior of cells is a ?
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cytokine
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extravisation is also known as ?
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diapedesis
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The term ? means clear fluid.
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serous
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The fluid that escapes when endothelial cells contract is called ? and this accumulation of fluid in the tissues is called ?
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exudate
edema |
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The tendency of cells to migrate in response to a specific chemical stimulus given off at a site of injury or infection is ?
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chemotaxis
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? are the first WBC's to the site of the infection.
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Neutrophils
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? clear pus, cellular debris, dead neutrophils, and damaged tissue
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Macrophages
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FUO stands for ?
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Fever of Unknown Origin
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The body temperature is normally maintained by a control center in the ? region of the brain and the temp is around ? Celsius or ? Farenheit.
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hypothalamus
37C 98.6C |
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Fever is initiated when a circulating substance called ? resets the hypothalmic thermostat to a higher temp.
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pyrogen
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Pyrogens are described as ? which means-coming from outside the body or ? (originating internally)
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exogenous
endogenous |
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? lymphocytes produce antibodies and ? lymphocytes kill intruders directly.
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B
T |
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? are general purpose phagocytes that react first in the inflammatory response and are a primary component of ?
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Neutrophils
pus |
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? are attracted to sites of parasitic infections and antigen-antibody reactions and only play a minor role in phagocytosis
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Eosinophils
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Special macrophages called ? migrate to a certain tissue and remain there during their life span.
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hystiocytes
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Lysosomes migrate to the scene of the phagosome and fuse with it to form a ?
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phagolysosome
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The benefits of fever are:
A.? B.? C.? |
A. inhibits multiplication of temp. sensitive microorganisms
B. starves bacteria of iron C. Increases metabolism |
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The 3 main types of phagocytes are ?,?,?
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neutrophils
macrophages monocytes |
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What are the 3 types of interferon?
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Interferon alpha, beta, gamma
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? pyrogens are products of infectious agents such as viruses, bacteria, protozoans, and fungi.
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Exogenous
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One well characterized exogenous pyrogen is ? the lipopolysaccharide found in the cell walls of gram(-) bacteria.
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endotoxin
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? pyrogens are liberated by monocytes, neutrophils, and macrophages during the process of phagocytosis.
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Endogenous
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