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20 Cards in this Set

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  • Back

what are some drugs that can increase BP?




what foods?




what some diseases can increase BP?

cyclosporine, tacrolimus, abuterol, steroids, contraceptives, decongestants, EPO, nsaids, venlafaxine




caffeine, alcohol, licorice, tyramine foods




ckd, sleep apnea, thyroid disease, cushings, aldostronism

what supplements/botancials are used in CV disorders?




what mind body therapies are used?

coenzymeq10, hawthorn, mg, flaxseed, garlic




relaxation response, biofeedback, transcendental meditation, yoga, qi gong, tai chi

what drug interactions occur with coenzymeq10?




is it effective?




how should you take this supplement?

warfarin, increase risk of clotting


other antihypertensives, may cause hypotension




yes, studies have shown it is POSSIBLY EFFECTIVE for HTN




with a fatty meal

what drugs can decrease CoQ10 in the body?

statins and beta blockers (propanolol)

what are the drug interactions with hawthorn??




how good is the efficacy?

nitrates, hypotension


phosphodiesterase 5 inhibitors, hypotension


digoxin, potentiates digoxin effects, decrease dig dose


antihypertesnives, hypotension




INSUFFICIENT RELIABLE EVIDENCE for HTN

what is the dose limiting side effect of mg?




any efficacy?




why is there an issue with the different forms of Mg




how should mg be taken?

diarrhea




INSUFFICIENT RELIABLE EVIDENCE for HTN




different bioavability and elemental iron




with food and at least 8 oz water

when is flaxseed considered unsafe?




what is the effect if you eat these?




durg interactions?

using raw or unripe flaxseed




incrases urinary excretion of thiocynates




antiplatelets, increase bleeding


antihypertensives, hypotension


antidiabetic, hypoglycemia


estrogens, decrease effects


may decrease absorption of other oral meds

efficacy of flaxseed?




how should flaxseed be taken?

INSUFFICIENT RELIABLE EVIDENCE for HTN




adequate fluid, 1 hr before or 2 hours after other meds

what is the main drug interaction with garlic?




efficacy?

can increase risk of bleeding




possibly effective

how does relaxation response work?




how does biofeedback work?







breathe slowly and deeply, repeat same word on each breath out




focus on controlling own breathing and heart rate

what does aspirin in men help reduce risk of?


what does asipirin in women help reduce risk of?




what botonaicals/supplements are used in CAD?

MI


ischemic stroke




fiber, sterols, niacin, red yeast rice, fish oil, coenzyme q10, folic acid, vit d, vit e

how does fiber reduce cholesterol?




what vitamin is niacin?

prevents absorption in gi tract




vitamin b3?

what are the contraindications to niacin?




what kind of niacin formulation has more heptatox?




why shouldnt niacin be used in diabetics?




what changes in urinary excretion? what can this cause?

acute liver disease or high lfts, active peptic ulcer, hypersensitivity, arterial bleeding




higher with slow release/exteneded release




impair glucose tolerance




less uric acid is excrted, can lead to gout, avoid in those that have gout attacks

what is a unique side effect of niacin?




efficacy?




how can you decrease the chance of the reaction described above?

flushing




likely effective




titrate slowly, use extended release, pretreat with asa or nsaid, take ir with meals, take sustained release at bedtime

what drugs should you not use red yeast rice with?




what can also be contained in red yeast rice that is a nephrotoxin?




efficacy?

gemfibrozil or other statins since it can increase risk of myopathy




citrinin




likely effective

drug interaction with fish oil?




what lipid does it reduce?




when are fish oil fda approved for treating trigs?

warfarin, increase risk of bleeding




trigs




if trigs are 500 mg/dL or greater

how can you reduce the fishy taste of fish oil?




how much fish oil should you take for effect?

freezer, take with meals, spread out dosing




4 grams

efficacy of coQ10 for CAD?




what vitamin is folic acid?




how is it supposed to work?




efficcacy?

possibly ineffective




vitamin b 9




reduces homocysteine levels




possbily ineffective for CAD

what element can increase if vitamin D is supplemented?




what electroyte balance can occur?




efficacy?

alumninum




hypercalcemia




insufficent evidence for hyperlipidemia

efficacy of vitamin e?




any other therapies?




what symptoms does it help with?

no benefit in hyperlipidemia




external counterpulsation




angina