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8 Cards in this Set

  • Front
  • Back

Adrenaline MOA

Naturally occurring catecholamine. A & B effects. Peripheral vasoconstriction.

Amiodarone MOA

Slow AV node discharge. Prolongs AV node conduction and refractory period. Blocks K efflux and Na channels. Vasodilation. Decreases O2 requirements.

Adenosine MOA

Interrupts reentry circuit involving AV node. Inhibits AV node conduction & increases AV nodal refractory period.

Atropine MOA

Anticholinergic agent. Blocks the transmission of parasympathetic impose from the vagus nerve. SA node conductivity accelerates, increases velocity through the AV node, this increasing HR.

Isoprenaline MOA

B1: increases myocardial contractility & HR.


B2: causes vasodilation.


Increases: HR, automaticity, contractility, systolic BP, myocardial O2 demand.


Decreases: diastolic BP.

Verapamil MOA

Slow calcium channel blocker. Slow AV conduction. Vasodilation. Decreases HR & force of contraction, decreasing workload and O2 demand.

Lignocaine MOA

Sodium channel blocker. Decreases membrane responsiveness & velocity of conduction. Decreases automaticity of the Purkinje fibres.

Digoxin MOA

Decreases impulse conduction in SA & AV nodes. Increases force of contraction by inhibiting sodium and increasing cellular calcium.