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35 Cards in this Set

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what are the corticosteroids used for allergic rhinitis

Fluticasone Nasal (Flonase)


beclomethasone


bedesonide


ciclesonide


flunisolide


mometasone


triamcinolone

what sx will you reduce by reducing inflm in allergic rhinitis

sneezing, itching, rhinorrhea, congestion

how long does corticosteroids to kick in for allergic rhinitis?

1-2wk


chronic therapy

ADR of corticosteroids for allergic rhinitis

rare systemic effects but reported


epistaxis


local effects

dose for corticosteroids for allergic rhinitis

Fluticasone Nasal Spray


50 mcg/spray


2 sprays each nostril qd

what are the leukotriene modifiers for allergic rhinitis

Montelukast (Singular)


Zafirlukast (Actovate?)

MOA of leukotriene modifiers for allergic rhinitis

inhibit leujotrienes


improved rhinorrhea, sneezing, congestion

ADR for leukotriene modifiers for allergic rhinitis

low rate: HA, dizziness, nasal congestion, skin rash

dose for leukotriene modifiers for allergic rhinitis

Singulair


10mg T qhs

what is the mast cell stabilizers

Cromolyn Nasal (NasalCrom)

MOA of mast cell stabilizer for allergic rhinitis

reduce release of histamine form mast cells locally

ADR for mast cell stabilizer for allergic rhinitis

nasal pruritus


irritation


epistaxis

dose for mast cell stabilizer for allergic rhinitis

NasalCrom


5.2mg/spray


1 spray in each nostril TID-QID

who is the anticholinergic for allergic rhinitis

Ipratropium Nasal (Atrovent)

MOA of anticholinergic for allergic rhinitis

block PSNS nerve effect (Vivian n. is postganglionic


vasomotor rhinitis

ADR anticholinergic for allergic rhinitis

HA, tasts perversion, xerostomia

what is does anticholinergics tx?

rhinorrhea, not pruritus or nasal congestion

dose for anticholinergic for allergic rhinitis

Atrovent Nasal Spray


0.03% 2 sprays each nostril BID-TID

what are the antihistamines

Loratadine (Claritin)


Diphenhydramine


Doxylamine


Chlorpheniramine


Brompheniramine


Desloratidine


Cetirizine


Fexofenadine


MOA of antihistamines

blocks histamine from activating receptor (need drug BEFORE histamine attaches)

topical anihistamines

decongestant effect


onset is faster then nasal corticosteroidsA

ADR of antihistamines

CNS- drowsiness (less in newer drugs)


confusion, dry mouth

dose for antihistamine

Loratadine


10mg qd

what is a decongestant

Pseudoephedrine (Sudafed)


Phenylephrine


Oxymetazoline

MOA of decongestant

vasoconstriction of blood vessels causing engorged tissue in nasal passage

decongestant and pregnancy

not recommended for pregnant women or breast feeding women

ADR of decongestant

cardiovascular- increases HR and BP


metabolic- increases glucose and BPH


CNS- seizures


endocrine- thyroid messed up

dose for decongestant

Sudafed 12hr


120mg BID

dose for decongestant nasal

Oxymetazoline Nasal Spray


0.05% 2 sprays each nostril BID

what are the antitussives

Dextromethorphan (Delsym)


Benzonatate


Codeine

MOA of antitussives

depression of medullary cough center


sigma receptor stimulation

ADR or antitussives

drowsiness, dizziness, GI upset, etc.



toxic in small children

dose for antiussive

Delsym XL liquid


30mg/5ml


10ml BID for cough relief



Benzonatate


100mg TID PRN of cough


what is different about Benzonatate

local anesthetic

cold/cough for infants

do NOT use <4 y/o (not recommended for 4-11 y/o either)