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16 Cards in this Set

  • Front
  • Back
What is rhinitis?
inflammation of the nasal mucus membrane.
What are the predisposing factors for AR?
1.Genetics
2.Family history of AR, asthma
3.Allergen exposure
4.Elevated serum IgE
5.Eczema
6.Higher socioeconomic class
7.Secondhand smoking
8.Positive allergy skin prick test
9.Early exposure to infections & animals is unknown
Seasonal AR
"Hay Fever"
Usually spring and fall when plants bloom
Which pollens match with the seasons?
Spring-Tree pollens
Fall-Weed pollens
Summer-Grass pollens
Perennial AR
Year round
Indoor allergens: House dust mite fecal proteins, Animal dander, cockroaches, mold
Allergic sensitization vs Allergic response
Exposure 1-Ige antibodies=sensitization
Exposure 2 & subsequent exposures-IgE interacts, inflamm mediators are released=response
What are the effects of histamine?
1.Stimulates irritant receptors
2.Pruritus
3.Vascular & mucosal permeability
4.Smooth muscle contraction
What is EPR?
Responds in seconds or mins
Release preformed mediatiors(histamines) & Newly generated mediators(leukotrienes)
What are the symptoms of EPR?
1.Congestion
2.Rhinorrhea
3.Pruritus
4.Sneezing
What is LPR?
Responds in hours
Recruit eosinophil,basophil,monocyte, lymphocytes leads to inflammation
Inflamm response responsible for persistent and chronic symptoms.
Inflamed mucosa becomes hyperresponsive=priming effect
What are the symptoms of AR?
1.Sneezing
2.Watery or clear rhinorrhea
3.Nasal congestion
4.Itching nose, eyes, throat,ears
5.Postnasal drip
6.Allergic conjunctivitis
What are limitations to normal daily functions?
1.General fatigue
2.Mental fatigue
3.Anxiety
4.Depressive disorders
What are complications of AR?
1.Disrupted sleep
2.Acute otitis media
3.Loss of smell or taste
4.Poor work or school performance
5.Structural facial & dental problems
6.Epistaxis
7.Chronic malaise & fatigue
8.Recurrent & chronic sinusitis
Diagnosis of AR
1.History
2.Physical exam(children)
3.Allergic shiners
4.Nasal crease
5.Adenoidal breathing(mouth breathing)
6.Nasal scrapings(eosinophils)
7.Allergy testing
What are the 3 types of allergy testing?
1.Percutaneous(skin tests)-wheal & flare reaction.
2.Intradermal
3.RAST
What is the wheal-and flare reaction?
1st generation anti-histamines(stop 3-5 days)
2nd generation anti-histamines(stop 10 days)