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198 Cards in this Set
- Front
- Back
Exercise physiology
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study of functional stages that occur during movement
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the movement is typically
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voluntary
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the movement is typically caused by
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muscular activity
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exercise physiology is..
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fundamental and applied. it used to only be applied
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to get into exercise physiology programs
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you need a lot of basic sciences
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the movement is often used as a stimulus to observe or promote a particular change
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ok
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the movement includes what kind of effects
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preventative and rehabilitative. ex phys includes both rehabilitation and prevention
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the movement is expressed in terms of
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work
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the international unit for movement is
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watts
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ergometer
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measures work; allow for controlled rate, amount, and precision of work
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independent unit ergometer can measure
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to as low as 1 watt
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the fundamental changes studied are expressed in fitness measures. fitness measures are 1 of 3 types
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- health related
-performance related - organic |
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the measures can be studied
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submaximally or maximally
i.e. everyone is familiar with measuring vo2 max as a performance measure |
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the study of exercise physiology is the plasticity and adaptability of body functions
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ya
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specific purposes of ex phys
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- decreased incidence and likelihood of chronic disease
- slow down the rate of progression of a chronic disease or disability - enhance or facilitate rehabilitation - increase the quality of life - enhance work or sport performance |
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3 subdisciplines (focuses of study) of ex phys
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sport physiology, work physiology, clinical exercise physiology
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sport physiology
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- deals w the art and science of training for optimal sport performance. uses principles of training that are based on physiological responses; athletes take themselves to the limits
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work physiology
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examines the physiological explanation influence of environmental and working conditions
- results in protection and increased productivity - evaluation of what it takes fitness wise to do a job - occupation ergonomics |
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clinical ex physiology
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- resulted from the use of ex phys in rehab prevention
- clinical ex physiologists dont do as much rehab as pt's but they do more prevention than them |
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primary & secondary prevention
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primary- decreasing the likelihood of first occurrence; done by identifying and manipulating risk factors associated w the disease
secondary- decreasing the duration or severity of the disease OR decreasing the likelihood of a second event |
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movement
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- there can be no life without movement
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movement is
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complex; you can divide it into its parts; the sum is always greater than the parts
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factors that affect movement
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- health and general physical condition of the person
- previous experience and skill level - motivation, anxiety, and fatigue - cultural setting and social expectations (i.e. if you were a jogger 30 years ago, youd get in trouble) - gender, age, heredity (heredity determines how much and the rate of ur improvement) - readiness for action, level of involvement, technique |
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movement can be 1 of 3 things
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exercise, physical activity, sport movement
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exercise
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purposeful, planned, typically uses some physiological measure to gage the intensity i.e. % of VO2 max, % of 1 RM;
-exercise programs are designed to improve 1 or more fitness components; i.e. strength, muscular endurance, vo2 max |
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physical activity
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any increase in metabolism above rest
- i.e. do ur own gardening - recommended- physical activity most days of the week - physical activity programs are designed to improve health- i.e. bp, cholesterol, etc - physical activity has a dose response - you CAN improve ur health without changing ur fitness |
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the foundation for all movement is
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energy
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most activities that are recommended last longer than
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1.5 minutes; aka theyre aerobic
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when you take bp
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its indirect. it is taken arterialy, over the brachial artery (medial side of arm)
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antecubital space
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where u stick the needle (front of elbow)
- cuff is placed above antecubital space |
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there needs to be enough space bw the ___ and the ___ so the two dont rub against each other
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cuff and stethoscope
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take bp on the side the heart is on. otherwise there may be a diff of like 20mm
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yep
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make sure theyre sitting
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mhm
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if theyre gonna exercise on a treadmill
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- take one seated, one on treadmill before exercise, and one during exercise
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at rest,"",,pump bp up to
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160-180mm
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in exercise situation,"",,pump bp up to
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200mm
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if person is near max,"",,pump bp up to
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220mm
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if someone is low on the vo2 max scale (i.e. lower 20%)
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- set goals for them, dont just tell them to exercise; also start slow. like aim for getting to 50%
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measure strength how
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1 RM; you have 5 tries otherwise its invalid bc theyll be tired
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when u do strength training
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- there are changes in muscle and nervous system. nervous system adapts quickly. in a few weeks, youll be able to up weight, etc. with muscle, the closer u get to 6 weeks is when u start seeing changes.
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you can put on 1-2lbs of muscle per month if u really try
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ya
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before doing 1 RM
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u should do it 4-6 times beforehand if youve never done it before (so the nervous system can get used to it); ur motor units will recruit more efficiently (i.e. only recruiting the muscles required for the 1 RM) when its used to the exercise
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most exercise programs you would recommend are
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20-30min long (aerobic)
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best overall measure of energy basis
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vo2 max
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exercise is often recommended in terms of
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vo2 max
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moderate intensity exercise is
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40-60% of vo2 max
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in an absolute way (in terms of mets), moderate exercise intensity is
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3-6 mets
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vo2 and exercise intensity are directly related
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linear relationship
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1 met=
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3.5ml/kg/min
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the clinical way to express vo2 max is in
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mets
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for most people 3-6 mets is moderate intensity, however
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it may be max for clinical patients
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vo2max is also known as
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maximal oxygen uptake, max aerobic capacity, or max aerobic power (max aerobic power is most used)
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vo2max is related to many systems
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i.e. if u have a respiratory problem, or joint problem, etc. it will affect your vo2 max
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vo2 max is the highest amount of oxygen consumed during maximum exercise
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ya
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can u exercise at higher levels once you reached vo2 max?
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yea, ur muscular system can allow u to do more. the amount of work u do is not just dependent on ur cardiac- but u can only do i.e. 120% of ur vo2max for a short time
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vo2max is limited by
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cardiac output AND the extent to which ur muscle can perform anaerobically
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vo2max is determined by
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o2 transport, carrying capacity, and extraction
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fick equation
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says that vo2= cardiac output-arteriole-venous o2 difference
vo2= CO-avo2 difference - CO= transport capacity - venous o2= extraction |
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submax
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50% dependent on CO, 50% dependent on avo2 difference
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extraction
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- capillary density becomes higher during exercise
- mitochondria density increses - oxidative enzymes involved - changes in hemoglobin |
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CO is the central side. avo2 diff is the peripheral side
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yea
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high intensity exercise
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60-85% of vo2max
75% CO, 25% avo2 diff |
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exercise intensity AND duration contribute to
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runner's high (endorphins)
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interval training will train ur heart better than just running submax
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ya
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limiting factor in determining vo2 max
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CO; most important factor in determining vo2 max
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how much can vo2 max improve?
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5-50%
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athletes will only improve
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around 5% in and out of season
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elderly will only improve
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around 5%
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if you go into space
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ur aerobic capacity will be lower when u get back
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in high altitudes
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ur vo2 max will be compromised
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typically, the best change youll see is
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20-25%; like someone who just starts an exercise program
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most of these changes take place within
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the first 6 months
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vo2 max does NOT predict
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endurance performance, but its necessary
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takes how long to maximize athletic performance
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7 yrs
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other factors in vo2 max
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initial level of fitness, training intensity, frequency, and duration;
- intensity is most important |
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there is a minimum and a ceiling in terms of improvement
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- minimum= 50-60% of vo2max
- maximum= 85% of vo2 max -manual labor- 40% of vo2 max -sedentary, overweight- can be around 40% -familiar environment and genetics combined- 50% of vo2 max -genetics by itself- determines 30% of vo2 max |
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how much does vo2 max change based on avo2 difference?
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it can change depending on the situation
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to increase vo2 max you have to increase
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the ability to extract oxygen
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how much can CO increase as a result of training?
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about 20%
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2 reasons why CO increases
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- increased edv (at the end of filling, how much blood is there); staying hydrated affects edv
- increased left ventricular mass (less likely to occur in older individuals) |
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plasma volume can increase as a result of training
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yup
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vo2 can also be related to organs like
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the heart, muscle mass, and lung volume
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avo2 difference
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diff bw o2 in arteries vs veins
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normal values
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a- 20ml/100ml
v- 15ml/100ml during exercise; v=5/100ml avo2 diff (extraction)= 5 at rest and 15 during exercise, when u do a-v |
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ml/100ml can also be described as
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vols %
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hemoglobin oxygen dissociation curve
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a curve that describes the effect of pH, temperature, and co2 on the ability of oxygen to be extracted from hemoglobin; esp during exercise
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hemoglobin and myoglobin
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- have an effect on avo2 difference
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1/3 of women of childbearing age have hemoglobin level problems
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ya
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capillary density
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- most muscle fibers have at least 1 capillary
- the more capillaries you have, the more circulation there is= more oxygen |
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mitochondria density
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-more mitochondria= more ability to extract oxygen
-mitochondrial enzymes |
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CO=
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CO=HR x SV
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HR doesnt really change as you keep exercising
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so it doesnt affect vo2 max. SV does
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red muscle fibers
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are about 3-5x improved in avo2 difference compared to white muscle fibers. so you can improve more if you have more red muscle fibers
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what determines vo2 max?
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the mode of exercise used
heredity |
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mode of exercise
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- vo2 max values are higher on treadmill, compared to cycling
- highest values are reached on treadmill, bike ergometer is 10-15% lower, and arm ergometer is 30% lower |
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heredity
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- genotype (ur training) vs phenotype (how well u can adapt)
- genetics and familial environment account for 50% of vo2 max - regional fat distribution is about 30% genetically determined - total body fat= 25% determined - max heart rate= 50% determined by genes - muscular strength= 15-40% determined by genes - physical work capacity= 70% genetically determined (how much work you can do) |
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how to express vo2 max
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l/min
- resting is around .2-.4 l/min - ml/kg - METs- typically expressed in METs. the tables that describe various METs. it is just a multiple of resting metabolism. 1 MET is resting. it is just the easiest way to describe |
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weight independent and weight dependent exercise
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- running is weight dependent; i.e. run a mile vs run a mile w ur backpack- its harder
- cycling is weight independent activity; i.e. bike a mile, then bike a mile w ur backpack is the same thing - elliptical- between running and cycling - if u wanna lose weight, RUN bc its weight dependent - if u wanna measure someone who does a weight dependent activity, express it in ml/kg if its running bc its weight dependent; express it in l/min if biking |
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people exercise because
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- vanity- look good
- feel good |
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you reduce your risk of _____by exercising
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cancer
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as you lose weight, your vo2 max goes up; however
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your cv fitness didnt actually go up, its just easier for you to do stuff bc ur lighter
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when trying to lose weight
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its easier to exercise rather than diet
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elite endurance athletes vo2max
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75-84 ml/kg
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typical college male/female
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40ml/kg, 34ml/kg
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male/female cross country skier
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94, 77
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the more muscle involved, the higher ur vo2
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ya
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age and vo2max
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you lose 10% vo2 per decade beginning around age 30
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a good master's endurance athlete (over age 50) would prob be around
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50 ml/kg. an untrained 50 year old would be around 28 ml/kg
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noticeable effects of heart disease in
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heart transplant patients. 17 ml/kg
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in a clinical setting, it is not always possible to measure vo2 max
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- instead we use maximal functional capacity or symptom limited capacity (as far as they could go before something like out of breathness, chest pain)
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requirements to measure vo2 max
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- there should be at least 50% of total muscle mass involved in the exercise
- the assumption must be made that the vo2 max is measured independent of motivation or skill |
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efficiency on bike or walking is
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25-30%
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efficiency in swimming is
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10-15%
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rowing is
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15%
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step ups and step downs are used in the clinical setting a lot too
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bench step vs treadmill- youll get about the same vo2 max
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more vo2 max reqs
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- assumption must be made that vo2 max is measured under standard lab conditions
- within some range of age predicted heart rate; 220-age + or - 12 - achievement of a significant systolic pressure; should be >180 - perception of RPE should be 19-20 - RER or R should be 1.10 or higher - lactic acid level should be 80mgs% or higher |
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muscle anaerobiasis
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- ur ability to tolerate anaerobic activity
- lactate clearance capacity- ability to clear lactate; after a point, u cant do it anymore - glucose-->pyruvic acid-->lactic acid or krebs cycle |
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during anaerobic activity, a lot of lactic acid is made
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yup. also, co2 is produced during the krebs cycle, as well as from buffering lactic acid. your breathing goes up i.e. on the treadmill bc you need to get rid of co2; the stimulus for breathing is the co2.
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at max exercise u hyperventilate
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hyperventilation- exhaling more than u are taking in. RER will be greater than 1.1 as a result
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ventilation
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7.5 l/min at rest
ventilation= 150-200 l/min during exercise |
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has workload goes up, vo2 goes up, then it levels out at a point
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yup
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inotropic
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- stroke volume
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chronotropic incompetence
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- being unable to achieve heart rate consistent with age predicted heart rate max
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when u dont respond to stimuli is when its bad
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yea
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Respiratory Quotient (RQ)
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VCO2/VO2- when this ratio is 1.0 or less than 1.0 ur using glucose as an energy source
6O2-->6CO2 |
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the degree to which you're hyperventilating should be minimally
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1.1
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the most notable change that happens during exercise
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respiration increase
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nervous system response intitiates
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the respiration
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resting lactate
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10%
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a well trained athlete @ the end of a competitive event (i.e. one lap around the track) will generate a lactate of
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150-200mg%
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a lactate of 200mg% will generate a pH around 7
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ye
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you dont start accumulating lactic acid til ur around
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50% of vo2 max
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the highest lactate is 357mg% with a pH of 6.8
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yea
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an elite mile runner has a 175 mg%
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40 minutes into recovery he was at 30mg%
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stereoids help u recover; however they screw with ur head
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ya
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half time for recovery
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15 minutes
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plateauing of vo2
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as workload goes up, vo2 goes up. at some point vo2 just levels off, even if work increases
- once u reach vo2 max, you measure vo2 every 20 seconds, 3 times, to make sure theres a plateau; the diff w them all should be <2ml/kg/min |
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attainment of vo2max is limited by
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CO and muscle anaerobiasis
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vo2 peak
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the highest point u reach in an exercise test if u dont meet the criteria above; its the same thing as maximum functional capacity
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some people experience a progressive decrease
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ye
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the inability to achieve a vo2 max is due to a variety of things
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- lack of motivation on subjects part
- bad exercise protocol- should last 10-12 min - mode of exercise; i.e. giving the runner a cycling test - age, medical condition, and disease state - symptoms that might occur or fatigue due to poor anaerobic capacity |
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jim ryan
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world record holder of the mile (3:51) vo2 max of 80 ml/kg
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don nash
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best mile time is 4:07
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best marathon runner
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69.7; eric clayton. could run it at 86.2% of his vo2 max.
- he was on the treadmill for 30 minutes at a 4:50 pace without increasing his lactic acid |
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calculated data; raw data
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putting an average of i.e. 3 scores into a calculation
raw data- the scores themselves |
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you cant always measure true vo2 max
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- in some cases you have to predict
- the smallest errors are around 5%; some tests can reach 20% - there are all kinds of walking tests, as well as endurance runs, non exercise data, cycling tests - endurance runs can be a problem bc of packing and motivation. i.e. on a 1.5 mile run, it really depends on how motivated you are in terms of how fast u run it; also people may start out running really fast and cant pace themselves - field tests- typically have motivation issues, which contribute to error - body mass and fats- can add to error associated w prediction; i.e. shaq is fit, but he has a lot of body mass and would have a hard time running 1.5 miles - efficiency- dont give them something new too quick i.e. if theyve never ridden a cycle before, ease them into it |
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lactate clearance capacity
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ur ability is somewhat dependent on how fast u can clear lactic acid
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hyperventilation
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- a function of lactate; as your lactate goes up you start to breathe more than u usually would
- a function of co2 buildup as well |
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anaerobic threshold
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- the point at which anaerobiasis starts to become the more reliable source of energy
- dont use this term tho! - use ventilatory threshold, or lactate threshold; lactate threshold is the best term, its just that its really hard to measure. - as workload increases, ventilation and lactate increase, and at a certain point they spike upward |
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another way to predict vo2 max
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base the prediction on what ur hr is, given the workload
- be aware that other things can affect hr too tho, like temp - u can only do this with aerobic stuff tho, not something like weight lifting, bc the workload to heart ratio is not always linear - u should know the linearity; to an extent, the linearity helps predict the vo2max |
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to predict-
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do 220-age, and find the given workload for it, then extrapolate to find vo2max
- there is a standard dev of + or - 12 for young adults - for a 50 year old or older, there is more than 12 - say u have a person thats above average and u rate them below average. that error would be around 2-% on ur part of predicting vo2 max |
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consider efficiency of exercise
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treadmill- best way to go. in particular walking
- but if a person is obese, the weight will affect efficiency, so you should cycle since the treadmill is a weight dependent activity cycling- will give u a little more trouble. you should not test them cold turkey bc most ppl dont cycle that much so u should ease them into it for a few weeks first |
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diurnal variation of submaximal heart rate
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about 5bpm
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most important determinants of vo2 max
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-exercise mode- type of exercising; the more muscles u use, the better the vo2 max will be
-heredity- determines 50% of vo2 max -the state of ur training- how active or inactive are u - gender- women are usually 15-30% lower than men bc of body composition and hemoglobin; body size determines what ur vo2 max is; bigger the person, higher the vo2 max - age- 10% decrease per decade starting at age 30 - the untrained 50 year old is 28ml/kg - the average college male is around 40 - trained is 52ml/kg - a transplant patient- 15ml/kg |
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stress
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disturbance in normal function; compromises homeostasis
- acute or chronic - maximal or submaximal |
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10-20% of athletes experience overtraining
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ye
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acute stress is like lab training
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ok
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10 RM= acute stress
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mhm
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Max RM is done in a lab setting
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k
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maximal stress can be done for
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sport, fitness, or clinical purposes
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submaximal testing
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more likely to be done by the general population, aged, or the clinically compromised
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submaximal setting cont
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done in clinical setting, research institute, or academic institution
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adaptation
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a more or less persistent change
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acclamation
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- there is an experimentally induced situation i.e. getting put in an altitude chamber
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climatization
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- a natural environment i.e. getting sent to denver
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habituation
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- refers to your behavioral perception of the situation
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stressors can be
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external, internal, or a combo
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external
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- temperature, hypoxic conditions, noise, light, physical threat, microbes
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internal
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- body temp, sleep, infection, fear, anxiety, internal clock, muscle tension, emotions, autonomic changes
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3 systems that respond to stress that function independently and cooperatively
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nervous, endocrine, immune
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nervous
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somatic vs autonomic
- both are responsive to stress - somatic- has to do w voluntary system - autonomic- deals w innervation of smooth muscle, cardiac muscle, and various glands |
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autonomic has
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sympathetic vs parasympathetic
- both have afferent and efferent fibers - sympathetic- activates and has a more diffuse effect; mobilizes body fuels, increases hr; fight or flight; the NT is norepinephrine, has alpha and beta receptors; beta receptors in heart rate are responsible for contractile force and rate - parasympathetic- typically localized effect; energy conserving |
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central (brain & spine & spinal nerves) and peripheral component
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central- coordinates things but is regulated and influenced by hormones
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endocrine system
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- most hormones are a general interaction and circulate widely in the body
-they have a very powerful effect despite being present in small quantities; nanongrams/ml |
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endocrine=
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hormones secreting
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endocrine system is made up of ductless glands that secrete into the extracellular spaces;
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as opposed to exocrine glands that have ducts (like sweat glands)
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endocrine system is made of
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glands, hormones, and target receptor organs
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weight of endocrine system
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a couple kg
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glands of endocrine system
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• Pituitary, thyroid, parathyroid, Thymus, pancreas, gonads, hypothalamus, fat tissue, adrenal glands, and pineal gland
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Effects of hormones
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• Activate enzyme systems
• Activate inactive forms of enzymes • Facilitate or inhibit uptake of certain substances • Alter membrane permeability • Stimulate protein or fat synthesis • Can initiate cellular secretion • Can have an effect on contraction or relaxation |
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2 types of hormones
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• Steroid derived hormones
• Non steroid hormones |
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stereoid hormones
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o Produced from cholesterol in adrenal cortex or gonads
o Lipid soluble- they can move thru cell membrane and have an effect on the nucleus |
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o 5 categories of steroid hormones
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-Glucocorticoids- responsible for increasing blood glucose i.e. cortisol (stress hormone)
-Mineralocorticoids- have an effect in terms of water and salt balance -Estrogen- the female hormone -Progestins- initiate and maintain pregnancy -Androgens- male hormones; i.e. testosterone every steroid has androgenic and anabolic characteristics. The % of each vary -Anabolic=muscle building; androgenic=more of male characteristics -females sometimes take androgenic steroids. Why? To lose body weight -Hitler took androgenic steroids; make you aggressive, mean, angry |
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non steroid hormones
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o Polypeptide based
o Soluble in plasma o React with receptors on cell surface o Effect is mediated by cAMP; Adenalyl cyclase is responsible for formation of cAMP o cAMP is a secondary messenger o u don’t know how many receptors there are on the cell surface; as many as 10,000 receptors per cell |
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o Immune system
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Heavy training depresses it.
• Heavy training decreases lymphocytes and antibodies= more susceptible to infection. • Increased incidence of infection after a single exhausting exercise session • Negative effects of excess training when transitioning from untrained to trained state; more likely to get sick until mayb 4-5 weeks in |
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- factors that can affect the outcome in terms of stress
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o your personal assessment of the stress
o your emotional response to the stress o your genetic characteristics o your age o the nature and duration of previous exposures o your control of the situation or your escape possibilities o your intelligence, education, and coping skills o the number of similar exposures |
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overtraining
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- 10-20% of athletes experience overtraining
- Overtraining results from inbalance bw training and recovery - Can be produced as a result of several days of hard training - Overtraining syndrome can be remediated by a few days of rest or a change in diet - overtraining has both psychological and physiological causes - highly individualized - its symptoms are subjective |
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syndrome
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refers to a group of signs and symptoms that characterize and abnormal condition
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- hard training that does not result in overtraining can be helped by increasing carb intake and rest
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carbs should be increased to 8.5g/kg body weight
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best indicators of overtraining
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o Sympathetic
Increase in sympathetic activity during rest Heart rate increases at rest Appear restless Impaired exercise performance Reflects not just being at rest, but other things too Affects emotional and psychological stresses that occur in everyday life impaired performance can be seen thru • ekg T wave inversion • higher lactate at submaximal exercise than usual • decrease in vo2 max • increase in oxygen consumption by as much as 10% at submaximal exercise submaximal exercise o Parasympathetic More common Increased vagal activity Chronic fatigue Altered sleep patterns and appetite Consistent feelings of fatigue Negative effect on reproductive function Mood disturbances Loss of interest in training |
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general symptoms of overtraining
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- General symptoms of overtraining
o Loss of enthusiasm o Loss of desire for competing/training o general malaise- don’t feel like doing anything |
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- hormonal changes that occur as a result of overtraining
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o significant changes in endocrine function
increase in thyroxin levels decrease in testosterone increased levels of cortisol (at rest cortisol levels are higher, they don’t go up (that much) during exercise, but they do when u overtrain) higher levels of urea • urea= a product of protein breakdown (the nitrogen component) aka protein breakdown occurs as a result of overtraining; blood urea nitrogen levels go up as a result of overtraining |
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cortisol
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o the stress hormone
o higher the intensity of exercise, the greater the response o can remain elevated up to 2 hours after exercise o most important effect- counters hypoglycemia (increases gluconeogenesis) o chronically high levels of cortisol can lead to negative nitrogen balance |
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ketosis
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happens bc cortisol accelerates fat mobilization; fat breaks down to aCoa, which can form ketone bodies
-ACoA (2C) -This is all a result of fat breakdown -Cortisol accelerates fat mobilization -Overtraining= results in energy source problems |
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more cortisol
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o increases gluconeogenesis
o cortisol is a steroid hormone o production is controlled by the hypothalamus o diurnal variation to cortisol; highest in the morning, lowest in the evening o its effects include proteolysis in the muscle o can lead to cramping muscle o suppresses the immune system o increases in blood glucose lvl o cortisol levels are elevated in obesity o elevated in stress (physical and mental) o cortisol=intensity dependent o must be at 60% of vo2 max to see significant increases in cortisol o cortisol can be measured in plasma or saliva o vary according to the phase of training you are in o sprinters and weightlifters have higher cortisol levels than endurance athletes o training mitigates its increase o training tends to lower the levels |
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the effect of a hormone is related to
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its half life
o half-life- the time it takes to reduce the concentration by 50% o epinephrine has a half life of 3 minutes o testosterone- 3.5 hours |
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- the effects of hormones are often looked at at a point of up regulation and down regulation
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o up regulation- the hormone can cause the cell to produce more receptors
o down regulation- refers to the loss of receptors |
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random last stuff
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R=RER; if R > 1.1, you are metabolizing something other than just carbohydrate; when u start exercising, R may be higher than RQ bc u already have co2 in ur tissues and it gets dumped out
RER= respiratory exchange ratio; RQ= respiratory quotient- reflects cellular processes (i.e. is it fat being metabolized or carb) |