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37 Cards in this Set

  • Front
  • Back
What is normal blood pH
7.35 to 7.45
What will changes in blood pH outside of normal range cause
hormone and enzyme fluctuation alterations, fluid and electrolyte disturbances, membrane excitability, decreased uptake, absorption, distribution and effectiveness of many drugs and hormones
What are acids
substances that release a hydrogen ion when teh substance is dissolved in water
What determines the strength of an acid
how easily the hydrogen ions is released
What is a substance that binds free hydrogen ions in solution
base
What is a substance that releases a hydrogen ion when the substance is dissolved in water
acid
What do strong bases do?
bind hydrogen ions easily
What do buffers do?
either release a hydrogen ion into a fluid or bind a hydrogen ion from a fluid
What are some sources of acids
glucose metabolism, metabolism of fats and proteins, anaerobic metabolism, destruction of cells
What are some sources of bicarbonate
carbonic acid breakdown, intestinal absorption, pancreatic production, movement of intracellular bicar into extracellular, kidney reabsorption
What are some acid base regulating mechanisms?
chemical, respoiratory, renal, compensation
What are the 2 most common chemical buffers?
bicarb buffers in extracellular fluid, phosphate in the intracellular fluid
What are the largest source of buffers
proteins
What is the major cellular protein buffer
hemoglobin
What are the 2 respiratory mechanisms to balance acid base balance
hyperventilation and hypoventilation
What are the renal mechanisms to balance the acid base balance
kidney movement of bicarb, formation of acids, formation of ammonium
What can the lungs compensate for
changes in metabolic disturbances
What can the renal system compensate for
an imbalance in the respiratory system or if the origin is metabolic
What are some parts of physical assessment for acid base balance
alert, moist mucous membranes, urine output and fluid intake are equal, good skin turgor, ABGs, BUN, creatinine, glucose, osmolartiy
What is H model
left axis (PaCo2) and the right axis (HCO3) and then use that to determine imbalance
What are some causes of metabolic acidosis?
overproduction of hydrogen ions; excess breakdown of fatty acids (DKA or starvation), hypermetabolism (anaerobic lactic acidosis), strenuous exercise, fever, seizures, tissue hypoxia, excessive intake of acidic substances (alcohol, methyl alcohol, acetylsalicylic acid)
What are some other causes of metabolic acidosis?
underelimination of H+ ions (kidney failure), underproduction of bicarb (reduced organ function), overelimination of bicar (diarrhea)
What are some lab asessements of metabolic acidosis?
decreased pH, decreased bicarb levels, noremal PaCo2 or carbon dioxide, elevated serum K+, normal or elevated chloride level
What are some interventiosn for metabolic acidosis?
hydration and meds to treat underlying cause of acidosis
What is the cause of respiratory acidosis?
impairment of any fucntion that causes inadqueate exchange of O2
What are some causes of respiratory acidosis?
chemical or physical respiratory depression, flail chest or broken ribs, respiratory muscles weakness, non respiratory conditions
How many airway obstruction cause respiratory acidosis?
restrictive clothing, edema, local lymph node enlargement, aspiration of foreing objects, internal obstruction of smooth muscle, excessive mucous, asthma, broncholitis, emphysema, decreased alveolar diffusion (pneumonia, TB, chest trauma)
What are some lab assessments for respiratory acidosis?
decreased pH, elevated paco2, low pa02, elevated serium potassium, variable bicar levels
What are some interventions for respiratory acidosis?
maintain patent airway and enhance gas exchange, drug therapy, oxygen therapy, pulmonary hygiene, ventilatory support and maintenance, prevention of complications
What may acidosis cause that is serious?
elevated serum potassium!!!!
What may cause acid deficit or metabolic alkalosis?
prolonged vomiting, Cushings syndrome, hyperaldosteronism, thiazide diurectics, prolonged NG suctioning
What may cause base excess or metabolic alkalosis?
overuse of antacids, citrate excess from massive or rapid blood transfusions, hyperalimentation, bicarb overcorrection
What are some lab assessments for metabolic alkalosis?
pH above 7.45, elevated bicar level (above 28), rising partial pressure of PaCo2, normal PaO2, decreased serum K+, decreased serum Calcium
WHat are some interventions fo metabolic alkalosis?
plan to prevent further loss of hydrogen, potassium, calcium, and chloride ions, drugs to resolve present imbalances, careful titration of fluids to maintain and prevent imbalance, monitor ABG
What is a cause of respiratory alkalosis
hyperventilation
What are some lab assessments of respiratory alkalosis
ph above 7.45, low bicarb level, low PaCo2, decreased serum potassium, decreased serum calcium
What are some interventions for respiratory alkalosis?
monitor ABGs, monitor for respiratory failure, hyperventilation, utilize O2 therapy, ventilator support as needed