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37 Cards in this Set
- Front
- Back
What is normal blood pH
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7.35 to 7.45
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What will changes in blood pH outside of normal range cause
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hormone and enzyme fluctuation alterations, fluid and electrolyte disturbances, membrane excitability, decreased uptake, absorption, distribution and effectiveness of many drugs and hormones
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What are acids
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substances that release a hydrogen ion when teh substance is dissolved in water
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What determines the strength of an acid
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how easily the hydrogen ions is released
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What is a substance that binds free hydrogen ions in solution
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base
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What is a substance that releases a hydrogen ion when the substance is dissolved in water
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acid
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What do strong bases do?
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bind hydrogen ions easily
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What do buffers do?
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either release a hydrogen ion into a fluid or bind a hydrogen ion from a fluid
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What are some sources of acids
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glucose metabolism, metabolism of fats and proteins, anaerobic metabolism, destruction of cells
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What are some sources of bicarbonate
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carbonic acid breakdown, intestinal absorption, pancreatic production, movement of intracellular bicar into extracellular, kidney reabsorption
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What are some acid base regulating mechanisms?
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chemical, respoiratory, renal, compensation
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What are the 2 most common chemical buffers?
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bicarb buffers in extracellular fluid, phosphate in the intracellular fluid
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What are the largest source of buffers
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proteins
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What is the major cellular protein buffer
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hemoglobin
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What are the 2 respiratory mechanisms to balance acid base balance
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hyperventilation and hypoventilation
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What are the renal mechanisms to balance the acid base balance
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kidney movement of bicarb, formation of acids, formation of ammonium
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What can the lungs compensate for
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changes in metabolic disturbances
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What can the renal system compensate for
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an imbalance in the respiratory system or if the origin is metabolic
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What are some parts of physical assessment for acid base balance
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alert, moist mucous membranes, urine output and fluid intake are equal, good skin turgor, ABGs, BUN, creatinine, glucose, osmolartiy
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What is H model
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left axis (PaCo2) and the right axis (HCO3) and then use that to determine imbalance
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What are some causes of metabolic acidosis?
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overproduction of hydrogen ions; excess breakdown of fatty acids (DKA or starvation), hypermetabolism (anaerobic lactic acidosis), strenuous exercise, fever, seizures, tissue hypoxia, excessive intake of acidic substances (alcohol, methyl alcohol, acetylsalicylic acid)
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What are some other causes of metabolic acidosis?
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underelimination of H+ ions (kidney failure), underproduction of bicarb (reduced organ function), overelimination of bicar (diarrhea)
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What are some lab asessements of metabolic acidosis?
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decreased pH, decreased bicarb levels, noremal PaCo2 or carbon dioxide, elevated serum K+, normal or elevated chloride level
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What are some interventiosn for metabolic acidosis?
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hydration and meds to treat underlying cause of acidosis
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What is the cause of respiratory acidosis?
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impairment of any fucntion that causes inadqueate exchange of O2
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What are some causes of respiratory acidosis?
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chemical or physical respiratory depression, flail chest or broken ribs, respiratory muscles weakness, non respiratory conditions
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How many airway obstruction cause respiratory acidosis?
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restrictive clothing, edema, local lymph node enlargement, aspiration of foreing objects, internal obstruction of smooth muscle, excessive mucous, asthma, broncholitis, emphysema, decreased alveolar diffusion (pneumonia, TB, chest trauma)
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What are some lab assessments for respiratory acidosis?
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decreased pH, elevated paco2, low pa02, elevated serium potassium, variable bicar levels
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What are some interventions for respiratory acidosis?
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maintain patent airway and enhance gas exchange, drug therapy, oxygen therapy, pulmonary hygiene, ventilatory support and maintenance, prevention of complications
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What may acidosis cause that is serious?
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elevated serum potassium!!!!
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What may cause acid deficit or metabolic alkalosis?
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prolonged vomiting, Cushings syndrome, hyperaldosteronism, thiazide diurectics, prolonged NG suctioning
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What may cause base excess or metabolic alkalosis?
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overuse of antacids, citrate excess from massive or rapid blood transfusions, hyperalimentation, bicarb overcorrection
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What are some lab assessments for metabolic alkalosis?
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pH above 7.45, elevated bicar level (above 28), rising partial pressure of PaCo2, normal PaO2, decreased serum K+, decreased serum Calcium
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WHat are some interventions fo metabolic alkalosis?
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plan to prevent further loss of hydrogen, potassium, calcium, and chloride ions, drugs to resolve present imbalances, careful titration of fluids to maintain and prevent imbalance, monitor ABG
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What is a cause of respiratory alkalosis
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hyperventilation
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What are some lab assessments of respiratory alkalosis
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ph above 7.45, low bicarb level, low PaCo2, decreased serum potassium, decreased serum calcium
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What are some interventions for respiratory alkalosis?
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monitor ABGs, monitor for respiratory failure, hyperventilation, utilize O2 therapy, ventilator support as needed
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