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26 Cards in this Set

  • Front
  • Back
hepatitis A. transmissio, incubation, manifestations
- spread thru fecal oral route
- incubation 15-50 days
- illness may last 4-8 weeks

manifestations
- mild flu like symp, low grade fever
- anorexia early symp
- later jaundice, dark urine
- indigestion
- enlarged liver/spleen
medical trtment for hepatitis A
- supportive
- bed rest during acute stage
- small frequent meals - 2000 to 3000 kcal/day during acute illness
- no alcohol
hep B transmission
- blood, saliva, semen, vaginal secretions
- sexually transmitted, vertical transmission during birthing, open cuts
hepC
- most common blood-borne infection
- causes 1/3 cases of liver cancer
- most common reason for liver transplant

- clinical course similar to hepB, but chronic carrier state occurs frequently - inc risk for cirrhosis and liver cancer
at what conc does jaundice occur
- bilirubin level greater than 2.5 mg/dl
types of jaundice and patho
- hemolytic - due to destruction of RBC
- hepatocellular - due to damage of liver cells
- obstructive - due to blockage of hepatic duct. body absorbs bile.
- hereditary - ie gilber's syndrome, dubin-johnson synrome
gilbert's syndrome
- a hereditray hyperbilirubinemia
dubin johnson syndrome
- a hereditray hyperbilirubinemia
SS of hepatocellular vs obstructive jaundice vs hemolytic
hepatocellular
- necrotic/ damaged liver cells, ie cirrhosis
- serum bilirubin, urine bilinogen rises
- ALT AST inc, indicating necrosis
- nausease, malise, fatigue, weakness, weight loss

Obstructive
- bile absorbed into blood
- urine deep orange and foamy
- stools pale b/c dec bile in GI
- dyspepsia and fat intol for same reason
- moderate rise in ALT, AST, GGT
- rise in serum bilirubin and alkaline phosphatase

hemolytic
- fecal and urine urobilinogen inc
- however, since there is inc of non water soluble uncojugated biliruben, urine is free of it (not orange)
AST, ALT
- enzyme lab values that indicate liver damage
- for both, above 40mg/dl indicates damage
portal hypertension
- obstructed blood flow through liver results in htn in portal venous system

- associated with cirrhosis and splenomealy
effects of portal hypertension
- ascites, and esoph varices
pt with painful abdominal distension and hemorrhoids
usually portal hypertension
varices
dilated tortuous veins - varicosities
cause of esoph varices
- usually portal htn
patho of esoph varices
- liver damage (cirrhosis) --> portal htn --> varices
manifestations of bleeding esoph varices
- hematemesis
- melena (tarry feces)
- shock symptoms
patho of cirrhosis
- scarring of liver tissue ( replacing with fibrotic tissue) affecting structure and function of liver
- mostly due to alchol intake

liver enlargement
portal obstruction --> ascites and esoph varices, edema
- infection
- edema
- mental deterioation
patho of cholelithiasis
= gall stones

pigment stones
- unconjugated pigments preciptate from bile
- must be removed surgically since can't be dissolved with meds

cholesterol stones
- dec bile acid synth inc cholesterol synth by liver
- may be able to dissolve
cholelithiasis aka
gallstones
signs of cholilithiasis
vague upper right quardrant pain, distress after fatty meal
patho acute pancreatities
- pancreatic duct obstruct
- enzymes back up into duct --> autodigestion and inflamm of pancreas
- assoc with ETOH
what drugs predispose a person for cholelithiasis
- estrogen
- oral contraceptives
- clofibrate

- these drugs increase biliary cholesteral saturation
clinical manifestations of choleliithiasis
biliary colic
- gall stones obstruct duct, causing distention, inflammation, and infection
- RUQ pain, radiates to back or right shoulder
- caused by contraction of gallbladder
- usually after eavy meal

jaundice

urine dark, feces pale

malabsorption of ADEK
what pain med should be used for cholelithiasis
- demeral preferred over morphine
- morphine causes contraction (sphincter of oddi)
nursing management for pancreatitis
pain
- frequenly assess pain and the effect of meds
- inc sever pain must be reported - may be hemorrhage of pancras or inadequate dose of analgesics

- oral feedings ceased to decrease secrtion of secretin
- bed rest to dec met rate and reduce secretion of pancreatic enzymes

- skin integrity at risk due to bed rist and poor nutrtional stats - assess