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11 Cards in this Set
- Front
- Back
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Phentolamine |
α1 & α2 selective
Actions: -hypotension -tachycardia
Uses: treat severe hypertension in medical facility
Problems: α2 receptor blockade effectively increases sympathetic tone & produces tachycardia |
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Prazosin |
α1 selective
Actions: -hypotension (by vasodilation, ↓ BP) -Tachycardia & activation of RAS (reflex to ↓ BP)
Uses: treat hypertension |
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Terazosin |
α1 selective
Actions: -hypotension (by vasodilation, ↓ BP) -Tachycardia & activation of RAS (reflex to ↓ BP)
Uses: treat hypertension
*4x Halflife of Prazosin* |
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Tamsulosin |
α1 selective
Uses: treatment of benign prostate hyperplasia (BPH) |
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Doxazosin |
α1 selective
Uses: treatment of benign prostate hyperplasia (BPH) |
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Propranolol |
β1 & β2 selective
Actions: -Cardiac depression (↓ heart rate, ↓ stroke volume, ↓ cardiac output, & ↓ BP) -Constriction of blood vessels that have β2 receptors -Brachioconstriction -↓ renin secretion, ↓ BP
Uses: -Essential Hypertension -Angina pectoris -Tachyarrhythmias -Congestive heart failures
Problems: -blockade of non-innervated β2 receptors in skeletal muscle arterioles & coronary arteries (causes constriction of these vessels) -blockade of innervated β2 receptors in bronchioles (causes bronchoconstriction) |
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Metoprolol |
β1 selective
cadioselective effects (no bronchial or blood vessel effects)
Actions: -Cardiac depression (↓ heart rate, ↓ stroke volume, ↓ cardiac output, & ↓ BP) -↓ renin secretion, ↓BP
Uses: -Essential Hypertension -Angina pectoris -Tachyarrhythmias -Congestive heart failures
Problems: -loss of sexual libido -enrectile dysfunction |
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Atenolol |
β1 selective
cadioselective effects (no bronchial or blood vessel effects)
Actions: -Cardiac depression (↓ heart rate, ↓ stroke volume, ↓ cardiac output, & ↓ BP) -↓ renin secretion, ↓BP
Uses: -Essential Hypertension -Angina pectoris -Tachyarrhythmias -Congestive heart failures
Problems: -loss of sexual libido -enrectile dysfunction |
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Pindolol |
β1 selective
cadioselective effects (no bronchial or blood vessel effects)
Actions: -Cardiac depression (↓ heart rate, ↓ stroke volume, ↓ cardiac output, & ↓ BP) -↓ renin secretion, ↓BP **may be partial agonist (↑ "resting" heart rate, ↓ "aroused" heart rate**
Uses: -Essential Hypertension -Angina pectoris -Tachyarrhythmias -Congestive heart failures
Problems: -loss of sexual libido -enrectile dysfunction |
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Labetalol |
α1, β1, β2 selective
-essentially like taking Prazosin + Propranolol
Actions: -Cardiac depression (↓ heart rate, ↓ stroke volume, ↓ cardiac output, & ↓ BP) -Antiarrhythmic -Bronchoconstriction -↓ renin secretion, ↓BP -Vasodilation (α1 blockade) -Vasoconstriction (β2 blockade)
Uses: Essentail hypertension |
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Carvedilol |
α1, β1, β2 selective
-essentially like taking Prazosin + Propranolol
Actions: -Cardiac depression (↓ heart rate, ↓ stroke volume, ↓ cardiac output, & ↓ BP) -Antiarrhythmic -Bronchoconstriction -↓ renin secretion, ↓BP -Vasodilation (α1 blockade) -Vasoconstriction (β2 blockade)
Uses: Essentail hypertension |
