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32 Cards in this Set
- Front
- Back
The Autonomic NS is divided into two parts they are ? |
The sympathetic division and the parasympathetic system |
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The sympathetic division does what ? |
Responds to emergencies and the need for energy. Promotes fight or flight. Inhibits non essential activities |
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The parasympathetic division does what? |
Restoration and conservation of body energy Rest and digest |
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What are the sympathetic divisions 4 'E's'? |
Emergency Embarrassment Excitement exercise |
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What does SLUDD stand for ? |
Salivation Lacrimation Urination Digestion Defecation |
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What does ACh stand for ? |
Acetylcholine |
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What does acetylcholine bind with? |
Nicotinic receptors (stimulated by nicotine) and Muscarinic receptors |
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Which neurotransmitter activates nicotinic receptors? |
Acetylcholine |
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What neurotransmitter activates muscarinic receptors ? |
Acetylcholine |
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Where are beta 1 receptors located ? |
Cardiac muscle |
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Describe the action of a drug that is an agonist ? |
It binds to and activates a receptor |
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Describe the action of a drug that is an antagonist ? |
It binds to and blocks the receptor |
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Name the two types of cholinergic receptors ? |
1. Nicotinic 2. Muscarinic |
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Name the neurotransmitter involved in cholinergic receptors ? |
Acetylcholine |
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Where would you find the cholinergic recpetor nicotinic ? |
Neuromuscular junctions and adrenal medullary cells |
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Where would you find the cholinergic recptor muscarinic? |
Effectors of the parasympathetic system (smooth muscle, cardiac muscle and glands) most sweat glands and skeleta muscle, blood vessels |
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Name the four different andrenergic receptors ? |
a1 - alpha 1 a2 - alpha 2 B1 - Beta 1 B2 - Beta 2 |
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Name the main location for alpha 1 receptors ? |
Smooth muscle in blood vessels, smooth muscle in iris |
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Name the main location for alpha 2 receptors ? |
Platelets, smooth muscle in some blood vessels, sweat glands |
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Name the main location for Beta 1 receptors ? |
Cardiac muscle, liver, uterus |
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Name the main location for Beta 2 receptors ? |
Smooth muscle of the lungs , liver and uterus |
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What is the main effect of stimulation of alpha 1 receptors ? |
Vasoconstriction of peripheral blood vessels and pupil dilation |
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What is the main effect of stimulation of alpha 2 receptors ? |
Platelet aggregation, dilation of smooth muscle and increased sweating |
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What is the main effect of stimulation of Beta 1 receptors ? |
Increased heart rate and increased contarctility of the heart |
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What is the main effect of stimulation of the Beta 2 receptors ? |
Bronchodilation and glycogenolysis ( relation of uterus) |
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Name the neurotransmitters that are involved with adrenergic receptors ? |
Adrenaline and noradrenaline |
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What neurotransmitter is the target of anticholinergic drigs ? |
Acetylcholine |
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Describe the effects of betablocker? |
Effects HR (decreases), decreases myocardial contractility, decreases BP bronchodilation |
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Name the main location of receptors (Betablocker) ? |
Heart and lungs |
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What effects would you expect to see if you administered an adrenoreceptor agonist ? |
↑ HR ,↑ BP, bronchodilation , pupillary dilation, ↓ GI motility, ↑ secretion of Adrenalin |
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Give an example of an adrenorecpetor agonist medication ? |
Adrenalin , salbutamol |
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Would anticholinergic drugs be considered agonist or antagonist ? Why ? Give an example |
Antagonist - they block receptors for ACh thus inhibiting the effect of ACh |