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32 Cards in this Set

  • Front
  • Back

The Autonomic NS is divided into two parts they are ?

The sympathetic division and the parasympathetic system

The sympathetic division does what ?

Responds to emergencies and the need for energy. Promotes fight or flight. Inhibits non essential activities

The parasympathetic division does what?

Restoration and conservation of body energy


Rest and digest



What are the sympathetic divisions 4 'E's'?

Emergency


Embarrassment


Excitement


exercise

What does SLUDD stand for ?

Salivation


Lacrimation


Urination


Digestion


Defecation

What does ACh stand for ?

Acetylcholine

What does acetylcholine bind with?

Nicotinic receptors (stimulated by nicotine) and Muscarinic receptors

Which neurotransmitter activates nicotinic receptors?


Acetylcholine

What neurotransmitter activates muscarinic receptors ?

Acetylcholine

Where are beta 1 receptors located ?

Cardiac muscle

Describe the action of a drug that is an agonist ?

It binds to and activates a receptor

Describe the action of a drug that is an antagonist ?

It binds to and blocks the receptor

Name the two types of cholinergic receptors ?

1. Nicotinic


2. Muscarinic

Name the neurotransmitter involved in cholinergic receptors ?

Acetylcholine

Where would you find the cholinergic recpetor nicotinic ?

Neuromuscular junctions and adrenal medullary cells

Where would you find the cholinergic recptor muscarinic?

Effectors of the parasympathetic system (smooth muscle, cardiac muscle and glands) most sweat glands and skeleta muscle, blood vessels

Name the four different andrenergic receptors ?

a1 - alpha 1


a2 - alpha 2


B1 - Beta 1


B2 - Beta 2

Name the main location for alpha 1 receptors ?

Smooth muscle in blood vessels, smooth muscle in iris

Name the main location for alpha 2 receptors ?

Platelets, smooth muscle in some blood vessels, sweat glands

Name the main location for Beta 1 receptors ?

Cardiac muscle, liver, uterus

Name the main location for Beta 2 receptors ?

Smooth muscle of the lungs , liver and uterus

What is the main effect of stimulation of alpha 1 receptors ?

Vasoconstriction of peripheral blood vessels and pupil dilation

What is the main effect of stimulation of alpha 2 receptors ?

Platelet aggregation, dilation of smooth muscle and increased sweating

What is the main effect of stimulation of Beta 1 receptors ?

Increased heart rate and increased contarctility of the heart

What is the main effect of stimulation of the Beta 2 receptors ?

Bronchodilation and glycogenolysis ( relation of uterus)

Name the neurotransmitters that are involved with adrenergic receptors ?

Adrenaline and noradrenaline

What neurotransmitter is the target of anticholinergic drigs ?

Acetylcholine

Describe the effects of betablocker?

Effects HR (decreases), decreases myocardial contractility, decreases BP bronchodilation

Name the main location of receptors (Betablocker) ?

Heart and lungs

What effects would you expect to see if you administered an adrenoreceptor agonist ?

↑ HR ,↑ BP, bronchodilation , pupillary dilation, ↓ GI motility, ↑ secretion of Adrenalin

Give an example of an adrenorecpetor agonist medication ?

Adrenalin , salbutamol

Would anticholinergic drugs be considered agonist or antagonist ? Why ? Give an example

Antagonist - they block receptors for ACh thus inhibiting the effect of ACh