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8 Cards in this Set
- Front
- Back
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What drugs are used for asthma?
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Beta 2 agonists-
1. Terbutaline 2. Albuterol |
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What drug is used for premature labor?
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terbutaline B2 agonist-uterine smooth muscle relaxation.
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Name 2 first generation beta blockers and why they are not used for treatment
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1. propranolol
2. timolol-glaucoma b/c they have variable bioavailibility due to plasma protein binding and first pass metabolism. |
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Name 3 second generation beta blockers and why they are better than first generation
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B1 selective blockers
1.metoprolol-better bioavailabiltiy 2.atenolol-not lipid soluble-decreased CNS effects 3.bisoprolol |
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Name 2 third generation beta blockers and how they work.
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1.Labetalol- for HTN, lowers TPR, little tachycardia
2.carvedilol- for HTN and HF non selective B blockers with additional actions |
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What are the possible mechanisms of action for B blockers that help with HTN?
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1.decreased renin from JGA
2.decreased Ca entry 3.increased K channels 4.NO production 5.blocks alpha Receptors 6. enhance Ne release |
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What are clinical uses of beta blockers?
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1.Angina
2.arrhythmias 3.HTN 4.Stage fright 5.Glaucoma 6.Migrane 7.Heart Failure |
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Why use beta blocker for heart failure?
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+
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