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22 Cards in this Set

  • Front
  • Back
inhibitor of catecholamine syntheis

treats pheochomocytoma associated hypertension

side effects: orthostatic hypotension, sedation

contraindications: hypersensitivity

used rarely
alpha methyltyrosine
inhibibitor of catecholamine storage used for hypertension

side effects: cardiac arrhythmia, GI hemorrhage, thrombocytopenia, dream anxiety disorder, impotence, psychotic depression, dizziness, nasal congestion

contraindicated: active GI disease, depression, electroshock therapy, renal failure
reserpine
inhibitors of catecholamine storage used for hypertension

side effects: kidney disease, apnea, orthostatic hypotension, fluid retention, dizziness, blurred vision, impotence

contraindication: MAOI therapy, heart failure, pheochromocytoma
Guanethidine and Guanadrel
inhibitor of catecholamine storage used for ADHD and narcolepsy

side effects: hypertension, tachyarrhythmia, Gille de la Tourett's syndrome, seizure, psychotic disorder with prolonged use, restlessness, dysphoric mood, rebound fatigue, addiction potential, loss of appetite, irritability, ED

contraindicated: advanced cardiovascular disease, glaucoma, hyperthyroidism, MAOI therapy, severe hypertension
Amphetamine and Methylphenidate
inhibitor of catecholamine storage used for allergic rhinitis and nasal congestion

side effects: Afib, ventricular premature beats, myocardial ischemia, hypertension, tachyarrhythmia, rebound congestion, insomnia

contraindicated: advanced cardiovascular disease, MAOI therapy, severe hypertension
pseudoephedrine
inhibitor of catecholamine reuptake used for mucosal and opthalmic local anesthetic and for diagnosis of Horner's syndrome pupil

side effects: accelerates coronary atherosclerosis, tachycardia, seizure, CNS depression or excitation, anxiety

contraindication: hyperensitivity
cocain
inhibitor of catecholamine reuptake used for depression, pain syndromes, nocturnal enuresis (i)

side effects: heart block, cardiac arrhythmia, orthostatic hypotension, MI, agranulocytosis, jaundice, seizure, worsening of depression, bloating, constipation, xerostomia, dizziness, somnolence, blurred vision, urinary retention

contraindications: MAOI, cardiac conduction system defects, MI recovery
Amitiptyline, Imipramine
MAOI used for depression

side effects: systemic tyramine toxicity, fever (increased muscle tone), leukopenia, hepatic failure, drug induced lupus, worsening depression, dizziness, somnolence, orthostatic hypotension, weight gain, increased liver amino transferase level, orgasm disorder

contraindications: use sympathomimetic, bupropion, buspirone, guanethidine, serotonergic, methyldopa, L-dopa, L-tyroptophan, L-tyrosine, phenylalanine, CNS depressants, narcotics, dextromethorphan, excessive chocolate/caffeine, foods with high tyramine; liver disease, pheochromocytoma, heart failure, general anesthesia, local anesthesia with vasoconstrictors
phenelzine, iproniazid, tranylcypromine, clorgyline, brofaromine, befloxatone, moclobemide, selegiline
alpha 1 agonist used for hypotension and shock

side effects: bradycardia (vagal reflex), ventricular ectopic beat, hypertension, vasoconstriction, nausea, headache, anxiety

contraindications: severe hypertension
methoxamine
alpha 1 agonists used for ophthalmic hyperemia, nasal congestion, and hypotension (p)

side effects: cardiac arrhythmia, hypertension, headache, insomnia, nervousness, rebound nasal congestion

contraindications: narrow angle glaucoma, severe hypertension or tachycardia (IV p)
phenylephrine, oxymetazoline, tetrahydrazoline
Alpha 2 agonist used for hypertension, opioid withdrawl (c), cancer pain (c)

side effect: bradycardi, heart failure, hepatotoxicity (m), autoimmune hemolytic anemia (m), hypotension, constipation, xerostomia, sedation, dizziness

contraindications: MAO inhibitor therapy and active liver disease (m)
clonidine, guanabenz, guanfacine, methyldopa
Beta agonist used in short term treatment of cardiac decompensation secondary to depressed contractility

side effects: bradycardia, asthma attack, widening of QRS complex, cardiac arrhythmias, hypotension, hypertension, palpitations, tachycardia

contraindications: idiopathic hypertrophic subaortic stenosis
dobutamine
beta agonist used for emergency treatment of arrhythmias, atropine resistant hemodynamically significant bradycardia, heart block and shock, bronchospasm

side effects: arrhythmias including Vfib, cerebral hemorrhage, severe hypertension, headache, nervousness, tremor, hypertension, palpitations, tachycardia

contraindications: tachycardia caused by digitalis intoxication, angina pectoris
isoproterenol
beta agonists used for asthma and COPD

side effects: dizziness, headache, tremor, restlessness

contraindication: hypersensitivity
Metaproterenol, terbutaline, albuterol, salmeterol
alpha antagonists used for pheochromocytoma associated hypertension adn sweating

side effects: seizure, postural hypotension, tachycardia, palpitations, xerostomia, sedation, miosis, absence of ejaculation

contraindications: severe hypotension, coronary artery disease
phenoxybenzamine, phentolamine
alpha antagonist used for hypertension, BPH

side effects: pancreatitis, hepatotoxicity, systemic lupus erythematosus, marked first dose postural hypotension, palpitations, dyspepsia, dizziness, sedation, increased urinary frequency, nasal congestion

contraindications: hypersensitivity
prazosin, terazosin, doxazosin
alpha antagonist used for BPH

side effects: pancreatitis, hepatotoxicity, SLE, dyspepsia, dizziness, sedation, increased urinary frequency, nasal congestion

less postural hypotension than prazosin
tamsulosin
alpha antagonist used for organic an psychogenic impotence

side effects: bronchospasm, nervousness, tremor, anxiety, agitation, increased blood pressure, antidiuretics

contraindications: chronic inflammation of sexual organs or prostate, concurrent use with mood altering drugs, gastric and duodenal ulcers, pregnancy, psychiatric patients, renal and liver disease
yohimbine
beta antagonist used for hypertension, angina, heart failure, pheochromocytoma, glaucoma

side effects: bronchospasm, atrioventricular block, bradyarrhythmia, sedation, decreased libido, mask symptoms of hypoglycemia, depression, dyspnea, wheezing

contraindications: bronchial asthma or COPD, cardiogenic shock, uncompensated cardiac failure, second adn third degree AV block, severe sinus bradycardia
propanolol, nadolol, timolol
beta antagonists used for hypertension and angina

side effects: bronchospasm, AV block, bradyarrhythmia, sedation, decreased libido, mask symptoms of hypoglycemia, depression, dyspnea, wheezing, hepatotoxicity (l)

contraindications: bronchial asthma or COPD, cardiogenic shock, uncompensated cardiac failure, second and third degree AV block, severe sinus bradycardia
labetalol adn carvedilol
beta antagonists used for angina and hypertension

side effects: bronchospasm, AV block, bradyarrhythmia, sedation, decreased libido, mask symptoms of hypoglycemia, depression, dyspnea, wheezing

contraindications: bronchial asthma or COPD, cardiogenic shock, uncompensated cardiac failure, second and third degree AV block, severe sinus bradycardia
pindolol and acebutolol
beta antagonists used for hypertension, angina, heart failure, thyroid storm (e)

side effects: AV block, bradyarrhythmia, sedation, decreased libido, mask symptoms of hypoglycemia, depression, dyspnea, wheezing

contraindications: bronchial asthma or COPD, cardiogenic shock, uncompensated cardiac failure, second and third degree AV block, severe sinus bradycardia

less bronchospasm then propolol
esmolol, metoprolol, atenolol, celiprolol