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12 Cards in this Set
- Front
- Back
Alpha and Beta Blocking agent |
Labetalol
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Alpha Adrenergic blocking agents, Non selective drugs
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Phenoxybenzamine Phentolamine |
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ADRs of Phenoxybenzamine |
nasal congestion miosis Orthostatic hypotension tachycardia |
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How is Phentolamine different than phenoxybenzamine |
Phenoxy = covalent bond, NONcompetitive (primarily at alpha 1) Phento = reversible, Competitive (at both alpha sites) |
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What is Tolazoline unique |
Beta activity (increase HR, CF, CO) Cholinergic (increase GI motility) Histaminergic (increase gastric secretions) |
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Selective Alpha-1 Blockers drugs |
PRAZOSIN Doxazosin Terazosin |
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Selective A2 blocker drug |
Yohimbine (only agent) |
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Nonselective Beta block drugs |
Nadolol Propranolol |
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Selective B1 block drugs |
Metoprolol Esmolol Atenolol |
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Main uses for Beta blockers |
Antianginal antihypertensive antiarrhythmic |
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Notable ADRs for Beta blockers |
CV: tachyarrhythmias, chest pain, cardiac failure CNS GI: dry mouth (denture patients) Respiratory: bronchospasm Musculoskeletal Derm Other: hypoglycemia (anti fight/flight) |
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Alpha and beta block drugs |
Carvedilol Labetalol |