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12 Cards in this Set

  • Front
  • Back

Alpha and Beta Blocking agent

Labetalol




Alpha Adrenergic blocking agents, Non selective drugs


Phenoxybenzamine


Phentolamine



ADRs of Phenoxybenzamine

nasal congestion


miosis


Orthostatic hypotension


tachycardia

How is Phentolamine different than phenoxybenzamine

Phenoxy = covalent bond, NONcompetitive (primarily at alpha 1)


Phento = reversible, Competitive (at both alpha sites)

What is Tolazoline unique

Beta activity (increase HR, CF, CO)


Cholinergic (increase GI motility)


Histaminergic (increase gastric secretions)

Selective Alpha-1 Blockers drugs

PRAZOSIN


Doxazosin


Terazosin

Selective A2 blocker drug

Yohimbine (only agent)

Nonselective Beta block drugs

Nadolol


Propranolol

Selective B1 block drugs

Metoprolol


Esmolol


Atenolol

Main uses for Beta blockers

Antianginal


antihypertensive


antiarrhythmic

Notable ADRs for Beta blockers

CV: tachyarrhythmias, chest pain, cardiac failure


CNS


GI: dry mouth (denture patients)


Respiratory: bronchospasm


Musculoskeletal


Derm


Other: hypoglycemia (anti fight/flight)

Alpha and beta block drugs

Carvedilol


Labetalol