Adrenal Steroids

Front 1

glucocorticoids

Back 1

type of corticosteriod responsible for control of carbohydrate, fat, and protein metabolism and are anti-inflammatory. An example is cortisol

Front 2

mineralcorticoids

Back 2

steroids that affect the blood salts--increases Na and Cl while decreasing K. Example is aldesterone

Front 3

sex steroids

Back 3

Estrogen and testosterone. they interact with the vertebrate androgen or estrogen receptors.

Front 4

corticosteriods

Back 4

class of steroids that are produced in the adrenal cortex. They are involved in a wide range of physiological systems such as stress, response, immune response and the regulation of inflammation, carbohydrate metabolism, protein metabolism, blood electrolyte levels, and behavior

Front 5

Adrenal Glands

Back 5

the endocrine glands that sit on top of the kidneys. Is split up into the medulla and cortex. Responsible for releasing hormones in conjunction with stress by stimulation from ACTH from the pituitary gland

Front 6

Zona Glomerulosa

Back 6

superficial layer of the adrenal cortex which is responsible for the production and secretion of aldosterone

Front 7

Zona Fasiculata

Back 7

Middle zone if the adrenal cortex which is responsible for production and secretion of glucocortoids (hydrocortisone)

Front 8

Zona Reticularis

Back 8

Innermost layer of adrenal cortex and superficial to adrenal medulla. responsible for production of androgens (precursors to sex steroids)

Front 9

Adrenocorticotropic Hormone (ACTH)

Back 9

A polypeptide tropic hormone secreted by the anterior pituitary gland. Is produced when biological stress occurs and its principle effects are increased production and release of corticosteriods. ACTH can used as an anti-inflammatory drug as well

Front 10

Cortisol

Back 10

MOA=enters cells where it stimulates DNA and RNA to produce enzymes that produce the hormonal effect. Is administrated IV/IM/PO with a duration for 2-6 hours. It produces anti-inflammatory effects, increased gluconeogensis and increased protein breakdown. Physiological effects are unknown. Adverse Effects are thin skin, hyperglycemia, increased BP, Na, and Cl, peptic ulcers, decreases antibody production and catabolic breakdown (lowers muscle mass)