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8 Cards in this Set

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Adenosine (Adenocard)

Class
Antidysrhythmic Agent; Endogenous nucleoside
Adenosine (Adenocard)

MOA
1. Slows conduction of the SA and AV nodes
2. Can interrupt reentry pathways through the AV and SA nodes
- used for chemical cardioversion
Adenosine (Adenocard)

Indications
SVT/PSVT unresponsive to Valsalva maneuver
Adenosine (Adenocard)

Contraindications
1. Hx of ‘Sick Sinus Syndrome’
2. 2nd/3rd degree heart block
3. Pts known to be taking Carbamazepine (Tegretol) or Dipyridamole (Persantine) as both will intensify effects
Adenosine (Adenocard)

Side Effects
Cardiovascular: chest pain/pressure, hypotension, transient PACs/PVCs, bradycardia, asystole, 2nd or 3rd degree heart blocks
Neurological: seizures, blurred vision, tingling/numbness, dizziness
Respiratory: shortness of breath/dyspnea, respiratory failure
Gastrointestinal: nausea, metallic taste
Other: flushed skin
Adenosine (Adenocard)

Precautions
1. Cannulate largest vein possible (and no smaller than 20 gauge IV catheter) to facilitate rapid flush following drug administration
2. Avoid administration with patients with bronchoconstriction or bronchospasms
3. Use very cautiously in COPD patients (i.e. those with emphysema or chronic bronchitis) due to respiratory failure side effect
4. Check current home medications prior to administration
Adenosine (Adenocard)

Interactions
Patient use of methyl-xanthines (i.e. Theophylline or caffeine) may render drug ineffective
Adenosine (Adenocard)

Routes / Dosages
Rapid IVP or IO

Adult: 6 mg rapid IVP/IO followed by 10-20 ml flush
May repeat with 12 mg twice after 1-2 minutes each

Pediatric: 0.1 mg/kg rapid IVP/IO followed by 10 ml flush
May repeat with 0.2 mg/kg once more after 1-2 minutes