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9 Cards in this Set
- Front
- Back
- 3rd side (hint)
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What environmental exposures are acute leukemias associated with?
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radiation, benzene, cytotoxic drugs, smoking
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Who gets AML?
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bimodal (neonates and adults)
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What is a t(15;17) ass with?
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Acute Promyelocytic Leukemia (PML /RARa)
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What are Auer rods?
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condensed granules in AML cells
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Tx for APL?
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alpha Trans Retinoic Acid (to induce maturation) followed by chemo
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None
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When do you use ARA-C?
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if your AML has a t(8; 21) or an inv16
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Who gets ALL?
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bimodal (2-5 and >60)
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Name the dz: fever, bone pain, fatigue, night sweats, high LDH?
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ALL
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What are the stages of therapy for ALL?
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induction (hematoligic remissionw/anthra, vincri, prednisone) Intensification (antimetabolites in adults) Maintenance (long term MTX)
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