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21 Cards in this Set

  • Front
  • Back
What are the three types of bacteria within the actinomycetes?
Nocardia
Actinomyces
Streptomyces
What kind of an organism is Nocardia? What "group" is it in?
Bacteria

Actinomyces
What kind of an organism is Actinomyces? What group is it in?
Bacteria

Actinomycetes
What kind of an organism is Streptomyces? What group is it in?
Bacteria

Actinomycetes
What is the morphology and staining of the organisms within Actinomycetes?
Thin
Filamentous; looks "beaded"
Branching
Gram positive
+/- acid-fast
What is the morphology of nocardia?
Gram positive
Acid-fast
Aerobic (different from actinomyces in this respect)
Branching
Filamentous
What does nocardia appear like in culture?
Granular
Brownish-white
Where in the environment is Nocardia found?
Soil
What population manifests Nocardosis?
IMMUNOSUPRESSED!

DON'T GET THIS WRONG AGAIN, JOHN!
What forms of immunity are important in Nocardosis?
PMNs/Macrophages
Cellular Immunity
What is the pathogenesis of Nocardia?
Inhaled from dirt into the lungs
Hematogenously spreads to other organs
What disseminated findings can be cause by an infection by Nocardia? Where?
Nodules/abscesses

Lungs
Brain
Skin
What are the most effective ways to diagnose Nocardosis?
Culture
Smear the purulent material
What is the treatment for Nocardosis?
Bactram for 6 months.
What is the morphology, staining, and oxygen status of Actinomycosis?
Gram positive
Weakly acidic
ANAEROBIC
Branching
Filamentous
What is the normal environmet of Actinomyces
Mouth
GI
GU tracts
What is a common presentation for an untreated infection by Actinomyces?
Lumpy jaw:
Large nonhealing abscess on the side of the mouth, penetrating from the mucosal surface to the skin to drain
Who is the typical host for an Actinomyces infection?
Healthy host
Post-surgical patients (disruption of mucosa)
Patients who have had dental work done.
What is the pathogenesis of Actinomyces?
Penetration through the oral mucosa and through the fascial pains
What is the most effective way to diagnose an infection by Actinomyces?
Culture

Smear of the purulent material: Gram +, Weakly acid fat
What is the treatment for Actinomyces?
Penicillin for 6-12 months