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32 Cards in this Set
- Front
- Back
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Bronsted-Lowry theory of acids and bases
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ACID Donates a Hydrogen Ion
BASE Accepts a Hydrogen Ion |
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Is a proton or electron is transfered in an Acid-Base rxn
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Proton
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Which is a stronger acid Organic or Inorganic
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Inorganic Acid is Stronger than Organic Acid
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Strong Acid
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an acid that gives up a H ion easily and is essentially 100% dissolved in H2O
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Weak Acid
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and acid that gives up an H with difficulty and is less than 100% dissociated in H2O
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Dissociation
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the splitting apart of an acid in H2O to give H ion and an anion
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How much H ion concentration can there be to maintain a normal pH 7.35-7.45
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44-36 nmol/L
(more H = more acidic and lower pH) |
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pKa
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onset of action of a drug
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why is CO2 a Volatile Acid
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b/c we breath it off as a gas
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How are Hydrogen Ions mainly produced?
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Protein Metabolism
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How much CO2 is produced each day from Aerobic Metabolism
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15-20 mols
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How much H ion is produced each day
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1mEq/kg (50-100mEq)
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Is H ion a volatile or non-volatile acid
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Non-volatile
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What kind of metabolism are H ions mainly produced by?
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Protein Metabolism
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Ratio of Bicarb: CO2
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20:1
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what does the Henderson-Hasselbach equation show
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it relates pH to levels of HCO3 and CO2
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What does pKa represent
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the pH at which 50% of an acid is dissociated (ionized) and 50% non-ionized
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solubility coefficient for CO2 in plasma
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0.03
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pKa of carbonic acid
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6.1 at 37 Celsius
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Buffer
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any substance that can reversibly bind Hydrogen ions (minimize or resist a change in pH)
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most important ECF buffer
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Bicarbonate (weak, organic acid)
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Renal tubular fluid buffer, ICF buffer
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Phosphate
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renal tubular fluid buffer
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Ammonia
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Most important ICF buffer
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Protein (Hgb)
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Poikilothermia
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when body temp equilibrates with ambient temp.
-created by anethesia |
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3 components of thermoregulation
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Afferent
central processing Efferent |
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core body parts
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chest
abd pelvis head |
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what makes up the peripheral body
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extremeties and skin
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shell depth
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2.5cm
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mean body temp =
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2/3 core + 1/3 surface
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how much heat is lost through the lungs
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1/3
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where are thermoreceptors located
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spinal cord
skin hypothalmus brain deep tissue skin surface 80% from core 20% periphery |
