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12 Cards in this Set

  • Front
  • Back
the most abundant buffer in ICF and blood plasma
protein
the main buffer protein in plasmo
albumin
acid
donates H+, gives up H+
base
accepts H+
an important buffer in RBC
Hemoglobin Hb
if excess H+, bicarbonate acts as a base to remove H+

if too few H+, carbonic acid acts as an acid to give off H+
Bicarbonate (HCO3-) and Carbonic Acid (H2CO3)
more carbon dioxide exhaled, increase in pH (less H+)
hyperventilation
increase in carbon dioxide and in H+, thus decrease in pH
hypoventilation
-major effect is depression of CNS, impairment of transmission of signals
- blood pH < 7
-can become disoriented and death is possible

-systemic arterial PCO2 >45mmHg
-caused by buildup of CO2 (and thus more H+)
-airways obstruction, disorders in the respiratory muscles
-caused by hypoventilation
acidosis
increased excretion of H+, reabsorption of HCO3 , tries to pick up more buffer such as bicarbonate
compensation for acidosis
-over-excitability in both CNS and periphery, conduction of impulses repetitively, resulting in nervousness, muscle spasms, convulsions and even death
-ph>7
-sysemic arterial pCO2<35mmHg
-caused by hyperventilation
-can occur in O2 deficient situations or conditions (altitude, pulmonary disease)
alkalosis
decreased secretion of H+ and reabsorption of HCO3 (which can bind to H+)
compensation for alkalosis