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66 Cards in this Set

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Mechanism of ace Inhibitor

Ace inhibits the converting enzyme from changing from angiotensin to angiotensin 2

Interactions of Ace Inhibitors

Nsaids- Reduced hypertensive affect


Lithium

Contraindications of Ace Inhibitiors

Lactating women


Children


Patients with bilateral renal stenosis, Patients with K over 5

Side effects of Ace Inhibitors

Angioedema, hypotension, interactable cough , HyperKalemia

Adverse of Ace inhibitors

Fatigue dizziness, mood changes, headaches

Ace Meds

Capropril


Trandopril


Enapril


Lisinopril


Prendopril


Ramipril


Fosinopril


Imidapril


Benazepril



Captopril

SE dizziness, fatigue, GI disturbance, productive cough, swelling of face and extremities


Evaluate WBC on regular basis


K may increase


Give 1 hr before meals



ARbs mechanism

Blocks action of angiotensin 2

Arbs end in what?

"Sartan"

Arbs used for

Hypertension only


Does not causae hyperkalemia

Contraindications of Arbs

Hyperkalemia

Arbs contraindication

Nsaids- could weaken the effectivness of the drug


Lithium


Rifampin- decreases arbs effectibness


Potassium possible hyperkalemia. Monitor levels



Toxcicty of ARBS

Hypotension and tachycardia


tx symptomatic and supportive

Arbs side effects

Chest pain, fatigue, hypoglycemia, diarrhea, UTI, Anemia,Hyperkalemia, and ciugl less likely to ocrur w/ ace

Calcium Channel Blocker Mechanism of action

Inhibit flow of calcium across the cell membrane relaxing smooth muscle through vasodilation reducing pressure of blood flow throughout the body

Calium channel blockers end in ?

Pine. Benzothiazpine, diltizem, Dihydropuyrides, amlodipine, felodipine, isradipine, micardipine, phenylalylamines, verapamil.

Popular calcium channel blocker

Diltiazem

Calcium channel blocker contraindications

Grapefruit juice


beta blockers


digoxin


amiodrone


azole antifungals


statins


cyclosporine

Dilitizem

Used for angina , atrial fib and nhypertension



SE of calcium channel

Dizziness, peripheral edema, arrythmias, nausea


Make sure patient has adequte liver function- these can cause LFT's to increase







Adverse effects of calcium channel blockers

Constipation- careful in elderly


Vertigo


Headache


Fatigue


Hypotension-we want this effect!

What happens on both legs with calcium channel blocers

Peripheral Edema can occure on both legs

Calcium channel contraindications

Known allergy


acute Mi


IV block


hypotension

Beta blockers end in

lol's

Beta bloker used to treat what?

Hypertension alone or in combination with diuretics

Contraindications for betablockers

Severe bradycardia


Heart blocks


Asthma


Heart failire

Mechanism of beta blockers

Decrease cardiac contractility decrease renin release which will decrease vasocontriction


Decreased blood pressure and decrease pulse

Things to watch out for on beta blockers

Blood sugar and watch orthostatic hypotension

Adverse of Beta blockers

Hypotension


bradycardia


fatigue


insomnia


sexual dysfunction

Who should avoid beta blockers

Diabetics because it drops blood sugar

Popular beta blocker

Propranolol

Propranolo can also be used for

hypertension, thyrotoxicosis, migraines, essential tremors

Propranolol Side effects

fatigue, lethargy, vivid dreams, sensitivity to cold, bronchoprasm, decreased BP, heart failure

Interactions/beware of beta blockers

Masks tachycardia and hypoglycemia


cause bronchioconstriciton


Do not give to an asmatic or anyone with chronic lung disease.


Can not stop abruply


can worsen CHF



What is antianginal

Suply of oxygen and nutrients in the bloos is insuffiencent to meed demains

What is Ischemia

Poor blood supply to an organ

what is MI

Necrosis or death of the cardiac tissue.

types of chronic angina

Chronic angina


Unstable angina


vasospatic angina

Drugs for Angina

Nitrates or nitrites


beta blockers


calcium channel blockers

Mechanism of action and drug effects of angial drugs

Cuases vasodilation because of relaxation of smooth mushce


dilating effect on myocardial tissue


prevent and treat angina

Rapid acting forms of nitrates

Used to treat acute anginal attacks

Long acting forms

Used to preven anginal episodes

Types of nitrates

Nitroglycerin -rapid/long


Isosorbide dinitrate - rapid/long


Isosorbid monoitrate - primarly long acting

Adverse effects of nitrates

Headaches, reflex tachycardia


postural hypotension


tollerance may develop

Tolerance on nitrates

Happens on patients taking nitrates around the clock or long acting forms



Nitrate patch when to remove

Remove at bedtime for 8 hrs then apply new patch in morning

Nitrates contraindication

*Hypotension


*Used of erectile dysfunction drug- silenafil (viagra), tadalafil (cialis), and varadenafil (levitra)


known allergy


severe anemia


glaucoma


severe head injury

Isosorbide Dinitrate

rapid acting sublingual tablets


immediate-release tablets


long acting oral dosage



Nitroglycerin

Used in the treatment of ischemic heart conditions such as angina


Routes PO SL metered dose aerosol that is sprayed under tongue IV and topical

Beta blocker treatment for Angina and?

Angina


MI


Hypertension


dysrhythmias



Types if angina beta blocker meds and mechanism

Atenolol


Metoprolol


Propranolol




Decreases heart rate

Anginal beta blocker indications

Angina


antihypertensive cardioprotective effects after MI


dysrhythmias


some migranes headaches tremors and stage fright

Beta blocker contraindication anginal

Bronchial asthma can promote bronchocontriction


diabetes mellitis, can mask hypoglycemia indused tachy cardia


PVD

Beta blockers adverse effects

Dizziness fatigue, depression, lethargy


impotence , wheezing, dyspnea

Patient taking beta blocker for MI what is the main benefit?

Slowing heart rate down

Calcium channel blockers for angina

*Amlodipine


diltiazem


verapamil

Mechanism of calcium channel blockers for angina

Causes coronary artery vasodilation


Peripheral arterial vasodilation

Calcium channel blockers indications

Angina


hypertension


coronary spasms



Calcium contraindications

hypotension


known allergy


acute MI


3rd av block

Calcium channel blocker adverse effects

May cause hypotension, palpitations


tachycardia, bradycardia, constipation


nausea, dyspnea

Nursing implications for angina

complete health hx


obtain baseline vitals, resp pattern and rate


patient needs to limit caffeine intake


patient to report, weight gain 2lb in 1 day or 5lb in 1 week


pulse rate less that 60 beats/min


dyspnea


Teach patient to change positions slowly

What does it man when burning sensation on nitrogycerine tablet

means the medication is still potent, never chew tablet

How long are nitrigycerin tablets potent for

Potency is lost in about 3 months after bottle has opened. Perserve potency medications stired in airtight dark glass bottle with metal cap no cotton filter.

Nitrogycerin path instructions

Remove patch before bed and apply new in the morning . With site rotation

CCB nursing implication

Constipation is a common problem, discuss patient to take adequate fluids and eat high fiber

Anti anginals drug nursing implciation

Monitir allergic reaction, headache, light headed hypotension dizyness