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16 Cards in this Set
- Front
- Back
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What effect do anabolic steroids have on protein synthesis?
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Increased
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Do anabolic steroids provide any aerobic benefit?
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No
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What effect do they have on the physes of skeletally mature individuals?
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Premature closure
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What effect does growth hormone have on muscle?
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Selective hypertrophy of type I muscle fibers
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What effect does growth hormone have on the physis?
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Proliferation without maturation (no premature closure)
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What effect does creatine have on (force x distance)?
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Increased work during the first few work anaerobic trials
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What effect does creatine have on peak force generated?
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None
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What are two nondepolarizing drugs?
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Curare
Pancuronium |
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How do nondepolarizing drugs work?
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Through competitive inhibition of acetylcholine receptors
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What is the clinical effect of nondepolarizing drugs?
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Relatively long duration of muscle paralysis
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What is an example of a depolarizing drug?
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Succinylcholine
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How do depolarizing drugs work?
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Temporary binding to the acetylcholine receptor site
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What is the clinical effect of depolarizing drugs?
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Shorter duration muscle paralysis
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What class of drugs can be used for reversal of these agents?
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Anticholinesterases
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What are two examples of anticholinesterases?
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Neostigmine
Edrophonium |
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Because they block the consumption of acetylcholine, what do their side effects include?
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Parasympathetic activation (acetylcholine hangs around longer)
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