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24 Cards in this Set

  • Front
  • Back

key similarities between bipolar and depression

1. shared symptoms


2. episodic, worsening course


3. familial and genetic overlap


4. frontal cortex and serotonin involvement


5. stress in key predictor of onset and relapse

important differences between bipolar and major depression

1. unique family and genetic influences on bi (bipolar much stronger)


2. dopamine and norepinephrine prominently involved in mania


3. very different medications are effective

current bottom line about bipolar vs major depression

1. shared risk factors lead to risk for depression


2. bipolar disorder is also associated with additional independent risk factors that may influence the dopamine system


3. related but distinct disorders

cognitive aspects of MDD

1. negative thinking/bias


2. rumination


3. learned helplessness


4. risk factors/consequences

negative thinking/bias in cognitive aspects of MDD

1. automatic negative and erroneous thoughts


2. cognitive triad--negative thoughts about self (internal), experiences (global), and the future (will always be this way; stable

rumination

dwell on negative mood, but don't act to change it

learned helplessness

1. perceived loss of control of reinforcements in life


2. hopeless re: potential to change

what could be risk factors or consequences of cognitive aspects of MDD?

1. tendency to ruminate predicts prior to depression (consequence of predict)


2. negative cognition after depression begins

anxiety disorders that share genetic diathesis

1. neg aff


2. GAD


3. panic disorder


4. dpecific phobia


5. social phobia


6. MDD

what is comorbidiy of MDD and most anxiety disorder explained by?

almost entirely explained by shared genetic risk factors

stress component of diathesis stress

anxiety--threat events (future)


depression--loss events

what possibly distinguishes anxiety and depression?

environmental factors and cognitions

in reality what distinguishes anxiety from depression

axiety is often a precursor for later depression

psychosocial treatments for major depression

1. behavioral therapy


2. cognitive therapy


3. interpersonal psychotherapy


4. couples/family therapy


5. other factors

behavioral therapy

increase positive activites/positive reinforcement

cognitive therapy

1. similar to anxiety--recognize and challenge negative cognitions


2. often incorporates some of the behavioral techniques as well

interpersonal psychotherapy

1. based on model that interpersonal problems lead to depression


2. address interpersonal deficits, loss, etc

couples/family therapy

address issues in the context of the couple dyad

pharmacological treatments for major depression

selective serotonin reuptake inhibitors


1. prozac, zoloft, paxil


2. increase availability of serotonin throughout the brain


3. hard to overdose


4. side effects: weight, sexual dysfunction



what works to treat disorders

1. psychosocial interventions


2. medication

medication

SSRIs are effective for at least some individuals


the combination of therapy and medicaation may be optimal (and this may be particularly true among adolescents and among those with severe depression

psychosocial interventions

1. behavioral, cognitive, interpersonal, and marital therapies all have documented efficacy


2. psychotherapy may reduce risk of relapse (although may need to continue therapy

treatment of bipolar disorder

1. lithium, antiseizure medication (depakote), atypical antipsychotics (abilify)


2 frontline treatment


3. adjunctive psychotherapy

frontline treatment for bipolar disorder

1. unethical in most c ases to treat bipolar disorder without medication


2. active mania=brain damage


3. significantly reduce risk of relapse and suicide


4. depressive phase of bipolar disorder is very difficult to manage


5. still not clear exactly how mood stabilizers work (but dopamine and serotonin and clearly involved)