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24 Cards in this Set
- Front
- Back
key similarities between bipolar and depression |
1. shared symptoms 2. episodic, worsening course 3. familial and genetic overlap 4. frontal cortex and serotonin involvement 5. stress in key predictor of onset and relapse |
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important differences between bipolar and major depression |
1. unique family and genetic influences on bi (bipolar much stronger) 2. dopamine and norepinephrine prominently involved in mania 3. very different medications are effective |
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current bottom line about bipolar vs major depression |
1. shared risk factors lead to risk for depression 2. bipolar disorder is also associated with additional independent risk factors that may influence the dopamine system 3. related but distinct disorders |
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cognitive aspects of MDD |
1. negative thinking/bias 2. rumination 3. learned helplessness 4. risk factors/consequences |
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negative thinking/bias in cognitive aspects of MDD |
1. automatic negative and erroneous thoughts 2. cognitive triad--negative thoughts about self (internal), experiences (global), and the future (will always be this way; stable |
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rumination |
dwell on negative mood, but don't act to change it |
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learned helplessness |
1. perceived loss of control of reinforcements in life 2. hopeless re: potential to change |
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what could be risk factors or consequences of cognitive aspects of MDD? |
1. tendency to ruminate predicts prior to depression (consequence of predict) 2. negative cognition after depression begins |
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anxiety disorders that share genetic diathesis |
1. neg aff 2. GAD 3. panic disorder 4. dpecific phobia 5. social phobia 6. MDD |
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what is comorbidiy of MDD and most anxiety disorder explained by? |
almost entirely explained by shared genetic risk factors |
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stress component of diathesis stress |
anxiety--threat events (future) depression--loss events |
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what possibly distinguishes anxiety and depression? |
environmental factors and cognitions |
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in reality what distinguishes anxiety from depression |
axiety is often a precursor for later depression |
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psychosocial treatments for major depression |
1. behavioral therapy 2. cognitive therapy 3. interpersonal psychotherapy 4. couples/family therapy 5. other factors |
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behavioral therapy |
increase positive activites/positive reinforcement |
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cognitive therapy |
1. similar to anxiety--recognize and challenge negative cognitions 2. often incorporates some of the behavioral techniques as well |
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interpersonal psychotherapy |
1. based on model that interpersonal problems lead to depression 2. address interpersonal deficits, loss, etc |
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couples/family therapy |
address issues in the context of the couple dyad |
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pharmacological treatments for major depression |
selective serotonin reuptake inhibitors 1. prozac, zoloft, paxil 2. increase availability of serotonin throughout the brain 3. hard to overdose 4. side effects: weight, sexual dysfunction |
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what works to treat disorders |
1. psychosocial interventions 2. medication |
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medication |
SSRIs are effective for at least some individuals the combination of therapy and medicaation may be optimal (and this may be particularly true among adolescents and among those with severe depression |
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psychosocial interventions |
1. behavioral, cognitive, interpersonal, and marital therapies all have documented efficacy 2. psychotherapy may reduce risk of relapse (although may need to continue therapy |
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treatment of bipolar disorder |
1. lithium, antiseizure medication (depakote), atypical antipsychotics (abilify) 2 frontline treatment 3. adjunctive psychotherapy |
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frontline treatment for bipolar disorder |
1. unethical in most c ases to treat bipolar disorder without medication 2. active mania=brain damage 3. significantly reduce risk of relapse and suicide 4. depressive phase of bipolar disorder is very difficult to manage 5. still not clear exactly how mood stabilizers work (but dopamine and serotonin and clearly involved) |