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4 Cards in this Set

  • Front
  • Back
Who described the mast cell?
Paul Erlich, 1878

"mast" means "feeding" or "fattening"
What is the critical growth factor for mast cells?
stem cell factor (cytokine)
Name the receptor on the mast cell that binds stem cell factor?
Receptor= kit

*kit is encoded by C-kit (protooncogene)
List the 3 types of mast cells and their location int the body.
1) MCt (tryptase)
-respiratory, intestinal mucosa
2)MCtc (typtase, chymase)
-skin, blood vessels, eyes, synovium, resp/intestinal submucosa
3)MCc (chymase)
-lymph nodes, intestinal submucosa, salivary glands