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7 Cards in this Set
- Front
- Back
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How does igm signall in the cell |
Tyr kinase src |
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How to activate b cell |
Igm to soluble: Ag & th cell & cytokines |
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How to class switch |
Major: igm and d - splice Minor: all others dna rearrange |
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What is affinity maturation |
Mutations selected = stronger affinity for ag bc tfh binds = faster signalling and replication |
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Which cytokines are responsible for each ab class to switch |
Iga - tgf b Ige - il4 Ign - ifn y |
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What is the function of abs |
Neutralisation Opsonisation Actuvate complement |
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What are the primary and secondary organs for wbc |
1ary bone marrow 2ary spleen, peyers patches, lymph nodes |
