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24 Cards in this Set
- Front
- Back
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cephalasporn moa
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same as penicclin
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drugs cephalasporn doesnt cover
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LAME
listeria, atypicals (chlamydia, mycoplasma), MRSA, enterococci |
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exception
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ceftaroline covers mrsa
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1st gen ceph
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cefazolin, cephalexin
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2nd gen ceph
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cefoxitin, cefaclor, cefuroxime
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3rd gen ceph
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ceftriaxone, cefoxitime, ceftasidime
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4th gen ceph
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cefepime
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1st gen ceph use
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PEcK
proteus, ecoli, klebsiella |
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cefazolin
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prevent staph infection prior to surgery
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2nd gen use
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HEN PEckS
hib, enterobacter, neiseria proteus, ecoli, klebsiella, seratia |
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ceftriaxone
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gonorrhea
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ceftazidime
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pseudomonas
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cefepime incrased activity
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pseudomonas
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ceph toxicity
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vit k deficiecy
disulfiram like reaction |
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ceph drug interactions
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increased nephrotoxocity with aminoglycosides
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aztreonam moa
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same as cillin resistant to beta lactamase, binds to PBP3
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aztreonam use
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GRAM NEGATIVE RODS
good to use in patients with penicillin allergy |
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ipipenem, meropenem moa
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same as penicillin
restisant to beta lactamse |
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mandatory codrug
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cilastatin with ipenem to inhibit renal dehydropeptidase I
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ipipenem/cilistatin, meropenem use
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everything, esp good for appendicitis
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vancomycin moa
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inhibits cell wall peptidoglycan by binding d-ala-d-ala portion of cell wall precursors
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vanc use
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gram pos only, especially mrsa, enterococci, and c diff (oral)
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vanc tox
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nephrotoxic, ototoxic, thrombophlebitis
Red man syndrome (pretreat with antihistamines and slow infusion rate) |
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vanc resistance
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d-ala-d-ala to to d-ala-d-lac
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