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16 Cards in this Set

  • Front
  • Back
HIV patient with eye infection, how do you differentiate between CMV vs HSV?
HSV - painful, b/l vision loss, widespread pale peripheral retinal lesions and central necrosis of retina, marked keratitis

CMV - painless, more common, fluffy or granular retinal lesions near retinal vessels, associated hemorrhages, does NOT cause initial conjunctivitis or keratitis
What are recommendations for MMR vaccine in HIV patients?
Give MMR vaccine to HIV patients with CD4 > 200, and NO prior aids defining illnesses

MMR does have live components, but is worthwhile b/c measels is such a high risk disease in HIV positive patients
What vaccines are contraindicated in HIV patients?
live vaccines

BCG
anthrax
oral typhoid
intranasal influenza
oral polia
yellow fever

if CD4 < 200 then MMR also
In HIV patients, when is PPD positive? What is tx?
PPD positive if > 5 mm

chemoprophylaxis is Isoniazid to tx TB, + pyridoxine to prevent neuropathy

9 months
What is the treatment for PCP pneumonia in HIV patient? When do you add additional drug?
IV trimethoprim-sulfamethoxazole

add oral prednisolone if PaO2 < 70
What does EBV DNA isolated in CSF of HIV patient mean?
primary CNS lymphoma

will have a weakly ring-enhancing mass, solitary and periventricular on MRI
What is a solitary, periventricular, weakly ring enhancing mass on MRI in HIV patient?
primary CNS lymphoma, will have EBV DNA in the CSF
What causes pulmonary cavitation in HIV patient?
Myco tuberculosis, atypical mycobacteria, Nocardia, gram neg rods, anaerobes
Immunocompromised patient has an infection with characteristic cutaneous and visceral angioma-like blood vessel growths, what microbe?
Bacillary angiomatosis, caused by Bartonella

constitutional symptoms, skin and viscera lesions

extreme caution w/biopsy bc will hemorage
What is best treatment for disseminated histoplasmosis?
Itraconazole
What prophylaxis is required in HIV patients with CD4 ct < 50?
Azithromycin for MAC (or clarithromycin)
What should you think of in HIV patient with bloody diarrhea and negative stool exam?
CMV, warrants colonoscopy biopsy
What causes bacillary angiomatosis? How does it present? How is it treated?
caused by Bartonella, gram-negative bacillus

bright red, firm, friable, exophytic nodules in an HIV infected patient

tx - oral erythromycin
What is treatment for toxoplasmosis?
Treatment - sulfadiazine and pyrimethamine

(prophylaxis - trimethoprim-sulfamethoxazole)
What are the associated HIV therapy reactions?

Didanosine -

Abacavir -

NRTIs-

NNRTIs -

Nevirapine

Indinavir -
Didanosine - induced pancreatitis

Abacavir - hypersensitivity

NRTIs - lactic acidosis

NNRTIs - Steven Johnson

Nevirapine - liver failure

Indinavir - crystal induced nephropathy
What is going on in HIV patient receiving tx that develops heamturia and needle-shaped crystal sediment?
Crystal induced nephropathy

2/2 Indinavir (protease inhibitor)