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75 Cards in this Set
- Front
- Back
d/ (40 fx of URINARY SYSTEM?
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1 - excretion
2 - regulation of H2O and electrolytes 3 - regulation of blood Ph 4 - regulation of BP |
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How big are kidneys?
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4" long by 2-3" wide
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Name (3) layers/capsules of kidney?
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1 - renal capsule (attach to visceral lining of kidney
2 - adipose (fat layer for protection 3 0 renal fascia (hold kidney against posterior wall |
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d/ PTOSIS?
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kidney come loose from wall, problem with renal fascia layer
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Fx of URETER?
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Carries urine to bladder
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Lenth of ureter?
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10-12"
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What kind of muscle tissue in ureter and what fx does it carry?
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Circulatory and long (as in stomach). Fx is peristalsis to move urine fr kidney
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Fx of BLADDER?
Bladder is a _______ muscular sac lined with 2 __________ epithelial cells (btwn squamous and epithelium). |
Hold urine, aid in micturation. Collapsible, transitional
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Fx of rugae in bladder
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allow for expansion
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d/ TRIGONE region of bladder
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Imaginary trangle shaped landmark btwn to ureter holes and urethra hole.
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How much does bladder hold normally and at what void is urge to void felt?
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700-800cc, 200cc
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Fx of URETHRA?
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singular muscular duct to outside of body
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d/ CORTEX region of kidney? What (3) things are housed here
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Outer portion of kidney. Has renal corpuscles, renal tubules, and blood vessels
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d/ RENAL CORPUSCLE (Bowmans Capsule)?
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consist of glomerulus and glomerular capsule
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d/ how blood gets filtered in GLOMERULUS?
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Blood is filtered b/c of high pressure, this is b/c insertion point is much larger than exit point of urine
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How would high BP stress the glomerulus?
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b/c pressure is normally high in glomerulus and cant afford any increase in pressure
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Everything is filtered from the glomerulus except for ___, ___, _______ b/c these molecules are too ____?
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RBC, WBC, and protein. Big
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If RBC, WBC, or protein are found in the urine this is _________ and means there is a problem with _________ ?
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abnormal, filtration
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The MEDULLA consist of what(5) parts?
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1 - Loop of Henle
2 - Collecting Tubules 3 - Blood Vessels 4 - Renal Pyramids 5 - Maj and Minor Calyces (calyx) |
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Describe the pathway of the filtrate in the kidney? Also describe which region of kidney these are (cortex or medulla)?
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1 - Capsule (cortex)
2 - Proximal Convoluted Tubule (cortex) 3 - Loop of Henle Start in cortex, mostly in medulla) 4 - Distal convoluted tubule (cortex) 5 - Collecting Duct (medulla) 6 - Minor Calyx (little room) 7 - major calyx (big room) 8 - Renal pelvis - 9 - Ureter |
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The Collecting Ducts (many grouped together) are also called _________ b/c of their resemblance?
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renal pyramid
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NEPHRON contain what (2) portions of kidney?
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Corpuscle and tubule
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how many nephrons are there in each kidney?
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1,000,000
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How much of our kidneys is it possible to live with?
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1/2 of 1 kidney
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_________ Nephrons connect to 1 collecting duct.
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Several
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The GLOMERULAR CAPSULE (Bowmans) consist of (2) layers?
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the parietal (cover inside, ) and the visceal layer (cover the glomerulus)
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What type of tissue on the parietal of the glomerular capsule?
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parietal is simple squamous and scalelike
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Glomerular capsule contain ______ ?
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Podocytes
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Fx of Podocytes?
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Wrap around the capillary to keep it from bursting (b/c of the incr pressure) and the water is filtered in btn the podococytes
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How will dehydration effect the endothelial pores?
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Fluid will be more viscous which wear down the endothelium and eventually will allow bigger stuff to come thru, similar to a broken screen.
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Blood enter the kidney thru the _______ ?
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Renal Artery
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d/ difference btwn AFFERENT ARTERIOLES and EFFERENT ARTERIOLES?
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Afferent take blood to the glomerulus and these are wider.
Efferent Take filtered blood from the glomerulus are narrower and have higher pressure. |
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Fx of the PERITUBULAR CAPPILARIES?
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pulls back into blood the things we dont want to lose
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Endothelium of glomeruli allows all but but _____ ______ & ______ _______ to be filtered out?
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large proteins and formed elements
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What is normal glomerular pressure?
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65 mm/Hg
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What is normal capillary bed pressure?
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35 mm/Hg
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d/ EFP EFFECTIVE FILTRATION PRESSURE formula?
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EFP = glomerular hydrostatic pressure 60 - (capsular hydrostatic pressure 30 + blood osmotic pressure 20)
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d/ formed elements
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RBC, WBC, Plt
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Capsular Hydrostatic pressure and blod osmotic pressure are (In or Out) pressures
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Both in pressure
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d/ CAPSULAR HYDROSTATIC PRESSURE?
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Pressure against the capsular wall. As stuff collects in the capsule it gives a little pressure back
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d/ OSMOTIC PRESSURE?
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If one solution inside cell mebrane is hypertonic and solution outside cell membrane is hypotonic then it pulls water in by osmosis to attain isotonicity
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Any kind of small blockage IE kidney stone will cause the ______ ________ _________ to go up and affect the EVP
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capsular hydrostatic pressure
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If Glomerular hydrostatic pressure (BP) goes up will have ____ filtration if it goes ____ b/c of low BP you will have less fitration
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high, low
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d/ TUBULAR REABSORPTION in peritubular capillaries
IE |
good stuff gets pulled back out from filtrate and back into blood. Water and solutes must first be reabsorbed into tubule cells then into capillaries
Na, CL, glucose, water |
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What (3) ways do peritubular capillaries selectivly absorb materials?
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1 - active transport
2 - osmosis 3 - diffusion |
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d/ active transport and what particles get moved in back into blood from tubules.
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Mvmt from area of high to low concentration.
Glucose, AA, Na Cl, and Sm Proteins |
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d/ OSMOSIS which takes stuff from filtrate into tubules
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diffusion of water which follows Na+ and Cl- (by active transport)
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d/ OBLIGATORY REABSORBTION and where does this occur and what %?
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80% of water that is reabsorbed in proximal tubules
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d/ FACULTATIVE REABSORBTION and where does this occur and what %?
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20% of water is reabsorbed in distal tubules
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How much water does kidney filter per day?
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45 gal/day
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How much fluid doe we lose per day?
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2 L/day
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What hormones (and what fluctuations) controls FACULTATIVE REABSORPTION?
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ADH (anti diuretic hormone) and Aldosterone. These hormones respond to fluctuating factors like IE amt of fluids taken in and temp outside etc.
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d/ ADH, where secreted from and fx in reabsorption
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Secreted by pituitary gland. increases water absorptions in the distal tubules. Responds to low fluid levels from not drinking enough
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d/ ALDOSTERONE, where it secreted from, and fx in reabsorption
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Secreted by Adrenal Cortex and helps to regulate BP
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d/ process of BP regulation by kidney?
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drop in BP thn sensed by kidney (
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Facultative reabsorbtion is controlled by what (2) hormones?
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ADH and aldosterone
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Fx of ADH? Where made?
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Anti Diuretic Hormone. Made by pituitary. increases water reabsorb in the distal tubules
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Fx of Aldosterone and BP regaulation mechanism? Where made?
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Secteted by Adrenal Cortex. Incr Na and water reabsorbtion
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Where are juxtaglomerular cells?
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Distal Tubules
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d/ FACULTATIVE REABSORBTION
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Drop in BP sensed by kidney (juxtaglomerular cells) THN JG cells sectrete Renin THN Renin stimul (1) Angiotensinogen to angiotensin 1 to angiotensin 2 (in lungs) THF strong vasoconstriction on incr BP (2cd) Renin stimulates release of Aldosterone (incr Na and Water reabsorbtion) and incr BP
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d/ TUBULAR SECRETION?
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Opposite of tubular reabsorbtion. When substances are secreted fr blood thru tubules to become urine
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What is given off in TUBULAR SECRETION?
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1 - drugs IE PCN
2 - Ions K, H, NH4 (ammonia) |
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What is fx of giving off H+ ions in tubular reabsorbtion
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H ions are what makes body acid, so body throws out H to control blood pH.
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What % of urine is water and solutes
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95% water and 5% solutes
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d/ normal color of urine and where does the color come from?
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transparent amber color, from urochrome in bile
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d/ normal pH of urine?
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4.8 - 8.0
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d/ (6) normal contents of urine?
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1 - urea
2 - uric acid 3 - creatine 4 - electrolytes 5 - toxins 6 - hormones |
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d/ (5) abnormal contents of urine?
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1 - glucose
2 - albumin 3 - pus 4 - blood 5 - stones |
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d/ what UREA in urine is from and what % is found?
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60-90%, from the deammination of protein which produces ammonia thn urea
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d/ what URIC ACID in urine is?
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from the breakdown of nucleic acids
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d/ GOUT
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buildup of uric acid crystals accumulating in blood and eventually in the feet
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d/ CREATINE in urine
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from creatine produced in from muscular contractions
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What ELECTROLYTES are in urine?
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Na, K, CL, HCO3
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Glucose in urine would indic _____ ?
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diabetes
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Protein in urine could indic _____ ?
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Problem in kidney
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