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7 Cards in this Set

  • Front
  • Back
What is the definition of a Cardiac cycle?
series of events that occurs during one complete heartbeat

electrical systole - spreading of depolarization wave by SA node

mechanical systole - contraction of cardiac muscle (P and V change), followed by relaxation

Closure and open of cardiac valves

generate heart sounds
What happens in the Atrial systole phase?
ventricles are relaxed

contraction of atria --> increased atrial P --> pressure gradient forces blood from atria to ventricles through opened AV valves --> rapid filling of ventricles

atrial muscle contraction prevents blood regurgitation

20-30 % (25 ml) of blood added to final ventricular filled volume (EDV, 130 ml)
What happens in the ventricular systole phase?
isovolumic and isometric contraction

increased intraventricular P --> reverse P closes the valves

volume remains constant

intraventricular P exceeds BP in aorta (80 mm Hg) and pulmonary trunk (20 mm Hg) --> semilunar valves open

Ejection:
-opening of aortic and pulmonary valves
-more P, blood is accelerated and ejected very rapidly from ventricles into arteries (70 % of blood in ventricles)
-aortic and pulmonary arterial P increases to systolic peaks
-ejection decreases P and ejection rate

SV:
-volume of blood ejected from each ventricle during ventricular systole

ESV:
-volume of blood in each ventricle after systole

ESV = EDV - SV

EF = SV/EDV X 100 (65 %)
What happens during Atrial and Ventricular Diastole?
Protodiastole:
-intraventricular P lower than arteries but kinetic energy keeps blood flowing
-backflow closes semilunar valves and ventricular chambers become closed

Isovolumic (isometric) relaxation:
-ALL valves close, P drop without drop in volume
-lower intraventricular P till it is lower than intra-atrial --> opening of AV valves

Ventricular Filling:
-relaxation of ventricular myocardium --> rapid filling
-ventricular P and volume increase --> reduced filling

last part of ventricular diastole is atrial systole --> RAPID active filling
What are the different heart sounds?
produced by vibration of closing valves and turbulent blood flow

First and second = S1 and S2 and loud enough to be heard through stethoscope

S3 and S4 are not loud

First heart sound:
-onset of ventricular systole (isovolumic contraction)
-low intensity and soft Lub
-closure of and vibration of AV valves

Second Heart Sound:
-beginning of diastole (protodiastole and isovolumic relaxation)
-high and sharp dub
-shorter than 1st sound
-closure and vibration of semilunar valve

3rd and 4th Heart Sounds:
3rd:
-end of rapid filling phase
-heard about 60 % of the time
-vibration of ventricular muscle
4th:
-not heard in normal people
-blood turbulence during atrial systole
What are Heart Murmurs?
abnormal heart sound from stenosis or incompetence of valve

-increase turbulence of blood through abnormal valve

innocent murmurs:
-occur in childen, not pathological

pathological murmurs:
systolic:
-mitral or tricuspid valve incompetence
-aortic or pulmonary stenosis
diastolic:
opposite
What affects Cardiac Cycle?
CC = 60 s/HR

increase HR = lowering CC

ventricular diastole is more affected than systole

0.12 is minimum interval for refilling of ventricles --> diastolic interval is the chief factor limiting maximal useful HR