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202 Cards in this Set
- Front
- Back
epithelial tissue
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skin
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Define "anatomy".
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scientific branch of study that investigates the body’s structure
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Anatomy also examines the relationship that exists between the ____a____ of a body part and its ___b____
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a) structure
b) function |
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Explain what "form dictates function" means.
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The anatomy (form) of a body part determines/indicates the physiology (function) of that body part.
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Give an example of "form dictates function".
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bones are able to provide protection because they are mineralized with calcium salts
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Define "physiology".
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the scientific investigations of the functions of living things
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Name the first "Major Goal of Physiology".
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understand how the body maintains conditions w/i a narrow range of values
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Name the 4 conditions listed in the notes as those "maintained w/i a narrow range of values".
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i. Temperature
ii. Heart rate iii. Blood pressure iv. Urinary output |
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Give the "textbook value" for temperature.
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98.6 degrees
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Give the "textbook value" for heart rate.
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72 beats per minute (bpm)
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Give the "textbook value" for blood pressure.
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120/80 mmHg
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Give the "textbook value" for urinary output.
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1.5 Liters/day
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Name the second "Major Goal of Physiology".
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b) understand and predict how the body will respond to stimuli/changes
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Name the 4 "Branches of Physiology" listed in the notes (not an exhaustive list).
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1) cellular physiology
2) neurophysiology 3) renal physiology 4) cardiovascular physiology |
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cellular physiology
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studies processes occurring in individual cells
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neurophysiology
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studies processes occurring in the nervous system
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renal physiology
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studies kidney function and the process of urine formation
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cardiovascular physiology
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studies the function of blood, the heart, and blood vessels
3 DISTINCT AREAS |
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List the "Levels of Structural Organization" from least to most complex.
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1) Chemical level
2) Cellular level 3) Tissue level 4) Organ Level 5) Organ system level |
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Chemical level
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a) atoms combine to form molecules
b) molecules combine to form cellular organelles |
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Cellular level
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a) cells= basic unit of life
b) all cells have a certain number of functions in common c) cells can also have unique functions |
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Give an example of a common function of all cells.
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cellular respiration
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Give and example of a function unique to some cells.
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contraction of muscle cells
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Tissue level
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a) a tissue= a group of functionally similar cells
b) 4 basic types |
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List the 4 basic types of tissues.
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i. epithelium
ii. muscle iii. connective iv. nervous |
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epithelium
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covers body surfaces and lines cavities
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muscle
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provides movement
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connective
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supports and protects
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nervous tissue
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provides communication through electrical signaling
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Organ level
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a) an organ is composed of AT LEAST 2 tissue types that perform a common function
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List examples of organs.
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kidney, liver, pancreas
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Organ system level
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a) a system is a group of organs that have a common function and are viewed as a unit
b) the body is divided into 11 distinct body systems |
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II. TERMINOLOGY AND THE BODY PLAN
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(section header)
|
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List the "Body Positions".
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1. anatomic position
2. supine 3. prone |
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anatomic position
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Subject is:
i. standing erect ii. facing forward iii. upper limbs are hanging at the sides iv. palms are facing forward |
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supine
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Subject is:
i. lying on its back, face upward |
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prone
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Subject is:
i. lying face downward |
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List the "Directional Terms".
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1) superior 6) lateral
2) inferior 7) proximal 3) anterior 8) distal 4) posterior 9) superficial 5) medial 10) deep |
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superior
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a. towards the head ("above")
b. a.k.a. "cranial", "cephalic" c. EX: the shoulder is SUPERIOR to the pelvis |
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inferior
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a. away from the head ("below")
b. a.k.a. "caudal" c. EX: the abdomen is INFERIOR to the neck |
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anterior
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a. in front of
b. a.k.a. "ventral" c. EX: the sternum is ANTERIOR to the spine |
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posterior
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a. in back of; behind
b. a.k.a. "dorsal" c. EX: the heart is POSTERIOR to the ribcage |
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medial
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a. toward the midline of the body
b. EX: the nose is MEDIAL to the eye |
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lateral
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a. away from the midline of the body; on the outer side of
b. EX: the ear is LATERAL to the eye |
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proximal
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a. closer to the point of attachment of a limb to the body trunk
b. EX: the elbow is PROXIMAL to the wrist |
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distal
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a. further away from the point of attachment of a limb to the body trunk
b. EX: the knee is DISTAL to the thigh |
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superficial
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a. toward the body's surface
b. a.k.a. "external" c. EX: skeletal muscles are SUPERFICIAL to bones |
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deep
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a. away from the body's surface
b. a.k.a. "internal" c. EX: the lungs are DEEP to the ribs |
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Name the 2 "Main Body Regions".
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a) axial- head, neck, trunk
b) appendicular- appendages/limbs |
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List the 3 "Main Body Planes".
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1. Sagittal
2. Frontal 3. Transverse |
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Sagittal plane
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vertical plane dividing the body into right and left halves
- mid-sagittal - parasagittal |
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midsagittal
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divides the body into equal halves (R & L)
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parasagittal
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divides the body into unequal halves
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Frontal plane
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vertical plane that divides the body into anterior and posterior halves
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Transverse plane
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a horizontal plane that divides the body into superior and inferior halves
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Name the 2 "Main Body Cavities".
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1) Dorsal body cavity
2) Ventral body cavity |
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Dorsal body cavity
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protects the nervous system
a. cranial cavity b. vertebral cavity |
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cranial cavity
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encases the brain
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vertebral cavity
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encloses the spinal cord
- located in dorsal body cavity |
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Ventral body cavity
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location of internal organs (viscera)
a. thoracic cavity b. abdominopelvic cavity |
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viscera
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internal organs
|
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thoracic cavity
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1. surrounded by the ribs and muscles of the chest
2. 2 subdivisions: a. lateral pleural cavities b. medial pericardial cavity |
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lateral pleural cavities
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each contains a lung
- located in thoracic cavity, w/i ventral body cavity |
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pericardial cavity
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encloses the heart
- located in thoracic cavity, w/i ventral body cavity |
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abdominopelvic cavity
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1. separated from the thoracic cavity by the diaphragm
2. 2 regions: a. abdominal cavity b. pelvic cavity |
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What does the abdominal region of the abdominopelvic cavity contain?
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stomach, intestines, spleen, pancreas, kidneys
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What does the pelvic region of the abdominopelvic cavity contain?
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urinary bladder, last portion of the large intestine, internal reproductive structures
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What is the "general" type of membrane in found in the ventral body cavity?
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serous membranes
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serous membranes
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double-walled membranes that:
1) covers organs 2) lines cavity walls |
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Name the 3 parts of the serous membrane(s).
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a) parietal serosa
b) visceral serosa c) serous fluid |
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parietal serosa
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the part of the membrane that lines the cavity walls
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visceral serosa
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the part of the membrane that covers the organ
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serous fluid
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thin layer of lubricating fluid between the serosas (visceral and parietal)
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List the "Specific Terms" under "Membranes in the Ventral Body Cavity".
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a) parietal pericardium
b) visceral pericardium c) parietal pleura d) visceral pleura e) parietal peritoneum f) visceral peritoneum |
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parietal pericardium
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lines the pericardial cavity
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visceral pericardium
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covers the heart's surface
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parietal pleura
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lines the walls of the pleural cavity
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visceral pleura
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covers the surface of the lungs
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parietal peritoneum
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lines the abdominopelvic cavity
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visceral peritoneum
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covers the surface of the organs in the abdominopelvic cavity
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III. THE CELL
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(section heading)
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Plasma membrane
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General Characteristics:
a) outermost component of cell b) responsible for the ability of the cell to connect, recognize, and communicate c/d) INTRAcellular vs. EXTRAcellular |
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The plasma membrane is responsible for the cell's ability to ___a___, ___b___, and ___c___ with one another.
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a) connect
b) recognize c) communicate |
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INTRAcellular
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describes substances INSIDE the cell
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EXTRAcellular
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describes substances OUTSIDE the cell
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Plasma membrane structure
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a) lipids: 45-50% of plasma membrane
b) proteins: 45-50% of plasma membrane c) carbohydrates: 4-8% of plasma membrane |
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Lipids in the Plasma Membrane
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i. phospholipids
ii. cholesterol |
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phospholipids
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lipids joined with phosphate groups arranged in two layers ("lipid bilayer")
- hydrophilic "head" - hydrophobic "tail" |
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hydrophilic "head"
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made of phosphate groups (polar)
- part of the phospholipid portion of the plasma membrane |
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hyrdrophobic "tail"
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made of fatty acid chains (nonpolar)
- part of the phospholipid portion of the plasma membrane |
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cholesterol in the plasma membrane
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interspersed between the phospholipids; prevents the fatty acid chains from sticking together
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Why is cholesterol important in the plasma membrane?
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by preventing fatty acids from sticking together, it maintains the fluidity/flexibility of the PM; this is critical to its function
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"fluid mosaic model"
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another name for the phospholipid bilayer
|
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Proteins in the Plasma Membrane
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i. suspended within the PM
ii. 2 types: - integral - peripheral iii. Functions: - attachment site - ion channels - receptor molecule(s) - marker molecule(s) |
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List the 2 types of protein in the plasma membrane.
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1) integral
2) peripheral |
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integral proteins in the plasma membrane
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inserted all the way through the PM; can communicate with the intracellular fluid and the extracellular fluid simultaneously
|
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peripheral proteins in the plasma membrane
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attached to either the inner OR outer surface of the plasma membrane
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List the functions of proteins in the plasma membrane.
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1) attachment site
2) ion channels 3) receptor molecule(s) 4) marker molecule(s) |
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Describe the function of proteins as ATTACHMENT SITES in the plasma membrane.
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allow cells to attach to each other or other molecules
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Describe the function of proteins as ION CHANNELS in the plasma membrane.
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allow ions (ie. Na, K, Cl, etc.) to move into or out of the cell
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Describe the function of proteins as RECEPTOR MOLECULES in the plasma membrane.
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sites on the outside surface of the plasma membrane that are *specific* for another substance; *binding* causes a chain of intracellular events
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Give an example of a protein in the plasma membrane acting as a receptor molecule.
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protein receptor site accepts acetylcholine (neurotransmitter) floating in the extracellular fluid... chains of events resulting in a muscle contraction (response)
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signal transduction
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a chain of events involving a receptor protein in the plasma membrane
receptor-> binding-> chain of events-> response |
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Describe the function of proteins as MARKER MOLECULES in the plasma membrane.
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allows for cellular recognition
|
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Give 2 examples of proteins in the plasma membrane acting as marker molecules.
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1) sperm cell recognizing oocyte
2) immune system recognizing "self" cells versus foreign cells |
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Carbohydrates in the Plasma Membrane
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i. glycolipid
ii. glycoprotein |
|
CHO + lipid = _______
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glycolipid
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CHO + protein = _______
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glycoprotein
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"cell coat"
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another name for glycolipids + glycoproteins in the plasma membrane
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IV. TISSUES
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(section heading)
|
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Name the 4 Tissue Types.
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1) epithelial
2) connective 3) muscle 4) nervous |
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Tissue classification is based upon:
1) ___________ 2) ___________ 3) ___________ |
1) structure of the cell
2) composition of non-cellular substances surrounding the cell (aka "extracellular matrix") 3) cellular function |
|
Epithelial tissue characteristics
|
a) covers some body surfaces and lines cavities
b) forms some glands c) retain mitotic ability d) an epithelial cell as 2 surfaces: - apical surface - basal surface |
|
Why is it important that epithelial cells "retain mitotic ability"?
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this allows damaged cells to be replaced with new cells
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apical surface
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the outside, exposed part of the epithelial cell (opposite the basal surface)
??? |
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basal surface
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the inner, unexposed surface of the epithelial cell (opposite the apical surface)
??? |
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Epithelial tissue with only one layer of cells is called ________.
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simple epithelium
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Epithelial tissue with multiple layers of cells is called _______.
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stratified epithelium
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List the functions of epithelial tissue.
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a) protection
b) secretion c) absorption |
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List the types of connective tissue.
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a) loose
b) dense c) cartilage d) bone e) blood |
|
List the "General Characteristics of Connective Tissue".
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a) all CT is derived from the same embryonic tissue type.
b) CT has lots of extracellular matrix. c) each major class of CT has a predominant cell type that exists in mature and immature form. |
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extracellular matrix
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nonliving structural portion of tissue that surrounds and separates living cells
|
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The extracellular matrix of CT can include 3 fiber types- list them.
|
1) collagen
2) elastic 3) reticular |
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collagen fiber
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- thick, fibrous protein
- extremely strong - most abundant * found in extracellular matrix of CT* |
|
elastic fiber
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- made of the protein elastin
- can stretch and snap back to original shape (recoil ability) * found in extracellular matrix of CT* |
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recoil ability
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describes the ability of a fiber to stretch and snap back to its original shape
-> essential for connective tissue in blood vessels, skin, lungs, etc. |
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reticular fibers
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- thin, fibrous protein
- mostly found around lymphatic tissue * found in extracellular matrix of CT* |
|
Give the predominant cell type for loose/dense connective tissue.
|
IMMATURE MATURE
fibroblast fibrocyte |
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Give the predominant cell type for cartilaginous connective tissue.
|
IMMATURE MATURE
chondroblast chondrocyte |
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Give the predominant cell type for bone. (CT)
|
IMMATURE MATURE
osteoblast osteocyte |
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Give the predominant cell type for blood. (CT)
|
IMMATURE: hemopoetic stem cell
MATURE: - erythrocyte-> red blood cell - leukocyte-> white blood cell |
|
How many different types of leukocytes are there?
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5 types
|
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List and describe the specific functions of loose connective tissue.
|
a) areolar- attaches skin to underlying tissues
b) adipose- aka "fat"; 2 types: - yellow - brown |
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yellow, adipose (loose CT)
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- used for storage, insulation, protection
|
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brown adipose (loose CT)
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- found mostly in the armpits, neck, and near kidneys
- used for generation of heat - newborns (neonates) have more |
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List the specific functions of dense connective tissue.
|
- regular
- irregular |
|
regular dense CT
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- protein fibers are all arranged in one direction (increases strength)
- found mostly in tendons |
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irregular dense CT
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- protein fibers are arranged randomly
- found where stretch in different directions is necessary (ie. skin) |
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Function of tendons?
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connect muscle to bone
|
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List the specific functions of cartilage.
|
1) hyaline (most abundant)
2) fibrocartilage 3) elastic (least abundant) |
|
hyaline cartilage (CT)
|
- made of small collagen bundles
- found where support and flexibility are needed (ie. nose, trachea, articulating surfaces) |
|
costal cartilage (CT)
|
type of HYALINE cartilage anchoring the ribs
|
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fibrocartilage (CT)
|
- made of large collagen bundles
- found in areas that withstand high pressure (ie. knee joint, b/w the vertebrae) |
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elastic cartilage (CT)
|
- made of elastin and collagen
- found in areas that are rigid but flexible (ie. external ear- "pinna") |
|
List the "Specific Characteristics of Bone"
|
- consists of living cells and mineralized matrix
- cancellous/spongy - compact bone |
|
Cancellous/spongy bone (CT)
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- made of flat bony plates called trabeculae
- between trabeculae are large open spaces filled with bone marrow - make up inner portion of most bones *honeycomb structure in a cross-section* |
|
Compact bone (CT)
|
- made of bony layers called lamellae
- very hard/solid because the lamellae have no spaces between them - outer covering of most bones |
|
Nervous tissue
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1. found in brain, spinal cord, and fibers extending from these areas
2. controls body through electrical signals called "action potentials" 3. 2 major cell types: - neurons/nerve cells - neuroglia |
|
neurons/nerve cells
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actual conducting cells of the nervous tissue; they PRODUCE action potentials
|
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neuroglia
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- 5 different types
- non-conducting support cells (do not conduct action potentials) - provide insulation and protection to neurons |
|
Muscle tissue
|
1. responsible for movement
2. contracts/shortens in response to electrical signals ... 5. 3 muscle types: - skeletal - cardiac - smooth |
|
Describe muscle tissue according to STRUCTURE.
|
a) striated- visible microscopic bands of contractile proteins
b) smooth- (non-striated) bands not visible |
|
Describe muscle tissue according to FUNCTION.
|
a) voluntary- consciously controlled
b) involuntary- unconsciously controlled |
|
contraction is accomplished by the interaction of cellular contractile proteins called __a__ and __b__.
|
a) actin
b) myosin |
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List the functions of the Integumentary System.
|
1. protection
2. body temperature regulation 3. sensation |
|
Describe the function of the Integumentary System in PROTECTION
|
a) chemical barrier
b) physical barrier c) biological barrier |
|
How does the integument form a "chemical barrier" for protection?
|
i. skin secretions are slightly acidic (low pH) which slows the growth of bacteria
ii. melanin protects against UV rays |
|
How does the integument form a "physical barrier" for protection?
|
i. continuity of skin and hardness of keratinized cells limits entry of foreign substances
ii. glycolipids make skin waterproof iii. hair iv. nails cover the ends of the fingers and can be used for protection |
|
Describe the function of hair in integumentary protection.
|
Hair forms a physical barrier:
- on the head provides insulation - eyebrows slow the flow of sweat into the eyes - in the nose and ears trap airborne particles |
|
Describe the function of the Integumentary System in BODY TEMPERATURE REGULATION.
|
a. an increase in temperature stimulates sweat glands to begin secretory activity
|
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How does sweat help regulate body temperature?
|
- evaporation of sweat pulls heat away from the skin and cools the body
|
|
Describe the function of the Integumentary System in SENSATION.
|
a. located in epidermis:
i. touch receptors b. located in dermis: i. touch receptors ii. pain receptors iii. temperature receptors iv. pressure receptors |
|
Merckel discs
|
TOUCH receptors located in the stratum basale of the epidermis
- function in sensation for integumentary system |
|
Meissner's corpuscles
|
touch receptors located in the dermis
- function in sensation for integumentary system |
|
nociceptors
|
PAIN receptors located in the dermis
- function in sensation for integumentary system |
|
thermoreceptors
|
TEMPERATURE receptors located in the dermis
- function in sensation for integumentary system |
|
Pacinian corpuscles
|
PRESSURE receptors located in the dermis
- function in sensation for integumentary system |
|
Describe how the Integumentary System forms "biological barriers" for protection.
|
i. Langerhan's cells
ii. dermal macrophages |
|
Langerhan's cells
|
- help activate the immune system
- located in stratum spinosum - function in PROTECTION for Integumentary system |
|
dermal macrophages
|
- phagocyte cells that defend against microorganisms
- located in the dermis - function in PROTECTION for the integumentary system |
|
List the "Clinical Disorders" of the Integumentary System.
|
1. Skin Cancer
2. Burns |
|
Skin Cancer
|
a. caused by a genetic predisposition and exposure to UV radiation
- 3 types: -> basal cell carcinoma -> squamous cell carcinoma -> malignant melanoma |
|
basal cell carcinoma
|
- least malignant
- most common form of skin cancer - begins in the stratum basale; tissue destruction produces an open ulcer - treated by surgical removal or radiation therapy |
|
squamous cell carcinoma
|
- cells in stratum spinosum continue unregulated cell growth (fail to lose mitotic ability after leaving stratum basale)
- in rare cases, the tumor migrates out of the epidermis and invades the dermis; if this occurs, the tumor can metastasize, and condition can become fatal |
|
malignant melanoma
|
- least common
- arises from melanocytes, usually in a pre-existing mole - develops as a large, flat, spreading sore, or a deeply pigmented nodule (hard "lump" under the skin) - metastasis is common; if not treated early this form is usually fatal |
|
Skin Disorders- Burns
|
a. categorized by depth of cell damage
i. 1st degree ii. 2nd degree iii. 3rd degree |
|
Skin Disorders- Burns- 1st degree burns
|
- involves epidermis only
- red and painful but heals in less than a week without scarring |
|
Skin Disorders- Burns- 2nd degree burns
|
- epidermis AND dermis are damaged
- burns are red and painful - edema usually develops - blisters develop - usually heal in 1-2 weeks; degree of scarring depends on extent of internal damage |
|
What is "edema"?
|
loss of fluid from blood vessels and into tissues- characterized by inflammation and swelling
|
|
Skin Disorders- Burns- 3rd degree burns
|
- epidermis and dermis are both completely destroyed
- skin can regenerate only from the edges; skin grafts are often necessary |
|
Tissues- Integument- THE SKIN
|
1. largest organ of the body
2. Epidermis 3. Strata layers |
|
The largest organ of the body, the __a__ is composed of __b__ regions.
|
a) skin
b) 2 regions (dermis and epidermis) |
|
Tissues- Integument- The Skin- EPIDERMIS
|
- outermost layer; superficial layer (epi=outer)
a. stratified squamous epithelium b. most cells contain the protein keratin (for protection) c. new cell production occurs by mitosis in deeper layers; surface cells desquamate |
|
T/F:
Cells in the epidermis undergo mitosis in the surface cells; deeper cells desquamate. |
FALSE
- new cell production occurs by mitosis in deeper layers; surface cells desquamate |
|
The Skin- Epidermis- STRATA LAYERS
|
"Cows Like Grain, Spinach, and Basil"
a. stratum corneum b. stratum lucidum c. stratum granulosum d. stratum spinosum e. stratum basale |
|
Epidermis- Strata Layers- STRATUM CORNEUM
|
1. most superficial
2. 20-30 layers of dead cells filled with keratin 3. Has waterproofing glycolipids that have been PRODUCED IN A DEEPER LAYER |
|
Where are the waterproofing glycolipids in the stratum corneum produced?
|
those glycolipids are produced in the STRATUM GRANULOSUM, by lamellated granules
|
|
Epidermis- Strata Layers- STRATUM LUCIDUM
|
- "clear layer"
1. 2-3 layers of dead cells filled with keratin 2. only present in thick skin (palms, soles of feet) |
|
Epidermis- Strata Layers- STRATUM GRANULOSUM
|
1. 3-5 layers of cells that are alive, but organelles are degenerating
2. 2 Types of Granule-Producing cells: a) keratinocytes b) Lamellar bodies |
|
Epidermis- Strata Layers- Stratum Granulosum- KERATINOCYTES
|
produce *kerataline granules*, which secrete keratin
|
|
Epidermis- Strata Layers- Stratum Granulosum- LAMELLAR BODIES
|
produce lamellated granules, which *secrete the glycolipid found in the stratum corneum*
|
|
Epidermis- Strata Layers- STRATUM SPINOSUM
|
1. has 5-7 layers of living cells
2. has melanin granules- produced in DEEPEST LAYER 3. has Langerhan's cells- immune system derived |
|
Where do Langerhan's cells migrate from?
|
Bone marrow- they're "immune system derived", but are found in the stratum SPINOSUM
|
|
Epidermis- Strata Layers- STRATUM BASALE
|
1. deepest layer
2. made of ONE layer of rapidly dividing epithelial cells that migrate to more superficial layers 3. has *melanocytes* that produce the melanin found in the stratum spinosum 4. has structures called "Merckel discs"= touch receptors |
|
Melanin is made in the stratum ___a___ by ___b___; it then migrates to the stratum ___c___.
|
a. basale
b. melanocytes c. spinosum |
|
Waterproofing glycolipids are made in the stratum ___a___ by ___b___, then migrate to the stratum ___c____.
|
a) stratum granulosum
b) lamellated granules c) stratum corneum |
|
Keratin is made in the stratum ___a____ by ___b___, then migrates to the stratum ____c____.
|
a) stratum granulosum
b) keratinocytes c) corneum |
|
The Skin- Accessory Skin Structures
|
1. Sweat glands
2. Sebaceous glands 3. Hair and hair follicles 4. Nails |
|
Accessory Skin Structures- Sweat Glands
|
a. eccrine/merocrine
b. apocrine |
|
Accessory Skin Structures- Sweat Glands- APOCRINE
|
1. less abundant, but larger than merocrine/eccrine
2. coiled secretory portion- (in dermis) has its releasing duct to open hair follicles- found in axillary and pubic regions |
|
Apocrine secretions contain ___a___ substances, which are ___b___ when secreted, but become ___c___ when bacteria acts upon them.
|
a. organic
b. odorless c. odiferous |
|
T/F:
Apocrine glands are not active in puberty. |
TRUE
|