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27 Cards in this Set

  • Front
  • Back
CHADS2 Score
CHF
HTN
Age
Diabetes
Stroke (2 Points)

0 = ASA, 1 = ASA/Warfarin/Pradaxa, 2 = Warfarin/Pradaxa
Paroxsymal
Less than 7 days
Persistent
Greater than 7 days
Recurrent
More than 2 episodes
Symptoms of AF
Palpitations, Exercise Intolerance, Fatigue on exertion, Cough, Chest pain/pressure, Diaphoresis, Dizziness,
RATE CONTROL
IV Beta Blocker or Nondihydropyridine CCB (if EF > 40%)
IV Digoxin or Amiodarone if < 40%
Verapamil Drug Interactions
Digoxin, Dofetilide (C/I), Simvastatin, Lovastatin (3A4 Inhibitor)
Which AF patients should use digoxin?
HF patients,
Hypotensive patients,
Pts who aren't physically active,
Patients who are contraindicated to BB or CCB
Metoprolol Dose
25 - 100 mg BID
Diltiazem Dose
Change from IV -> PO
120-360 mg/day
IV dose X 3 + 3 X 10
Verapamil Dose
120-360 mg/day
Digoxin
0.125-0.375/day
High Risk Factors for CHADS2
Previous CVA, TIA, or VTE
Mitral Stenosis
Prostetic Heart Valve
Moderate Risk Factors
Age > 75 yo
HTN
DM

HF
EF < 35%
Class I Anti Arrhythmics
Sodium Channel Blockers
Disopyramide (Norpace)
Procainamide (Procanbid)
Quinidine (Quinidex/Quinaglute)
Class IB
NOT FOR ATRIAL ARRHYTHMIAS
(Lidocane, Mexiletine, Tocainide)
Class IC
DO NOT USE IN PATIENTS WITH STRUCTURAL HEART DISEASE
Flecainide (Tambocor)
Propafenone (Rythmol)
Class II
Beta Blockers

only used for rate control
Class III
Potassium Channel Blockers
Amiodarone (Pacerone, Cordarone)
Amiodarone Interactions
Warfarin (decrease dose by 25-50%)
Digoxin (Decrease dose by 50%)
Statins (Lovastatin max does = 40 mg, Simvastatin max dose = 20 mg)
If using Amiodarone with a Statin, which should you use?
Can use Pravastatin, Fluvastatin or Rosuvastatin instead
Amiodarone ADRs
Pulmonary Fibrosis, Hypo/Hyperthyroidism, Hepatotoxicity, Optic Neurpathy, Bradycardia/Heart Block, Photosensitivity/Change in skin color, Neurologic effects (tremor, ataxia, peripheral neuropathy)
Dronedarone (Multaq) ADRs
Inhibits 3A4 and 2D6
Shorter half like
No Thyroid function problems
Hypokalemia
C/I: NYHA Class IV or Class 2-3 if recent hosptialization
2nd/3rd degree heart block
Long qt interval
Hepatic Impairment
Pregnancy/Nursing
3A4 Inhibitors
Verapamil, Azoles, Macrolides, Cyclosporine, Ritanovir
3A4 Inducers
Rifampin, Phenobarbital, Carbamezepine, St. Johns Wort
Class III
Potassium Channel Blockers
Amiodarone
Multaq
Dofetilide (Tikosyn)--Monitor for 3 days
Ibutilide (Covert)
Sotalol (Betapace AF) Monitor 4 hours
What dose of aspirin to take?
81-325 mg daily