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10 Cards in this Set
- Front
- Back
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What is the origin of DNA replication?
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Consensus sequence of base pairs in genome where DNA replication begins
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What is the DNA replication fork?
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Y-shaped region along DNA template where leading and lagging strands are synthesized
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What is DNA Helicase?
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Unwinds DNA template at replication fork
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What do single-stranded binding proteins do?
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Prevent strands from reannealing
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What does DNA topoisomerase do?
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Creates a nick in the helix to relieve supercoils created during replication
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What does primase do?
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Makes RNA primer on which DNA can initiate replication
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What does DNA polymerase III do?
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Prokaryote only
Elongates leading strand by adding to the 3' end, elongates lagging strand until it reaches primer of preceeding fragment |
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What does DNA polymerase I do?
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Prokaryote only
Degrades RNA primer, replaces it with DNA |
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What does DNA ligase do?
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Catalyzes the formation of phosphodiesterase bond within strand of dsDNA (joins okazaki fragments)
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What does Telomerase do?
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Enzyme adds DNA to 3' ends of chromosomes to avoid loss of genetic material with every duplication
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