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9 Cards in this Set

  • Front
  • Back
What do thyroid hormones do?
Iodine-containing hormones that control the bodies metabolic rate
Where is T3 created?
Follicles of the Thyroid
Where is T4 created?
Formed in target tissues from conversion of T3
What are the 4 functions of the Thyroid hormones (4 B's)?
Bone growth
Brain (CNS) maturation
increase B1 receptors of the heart (increase CO, HR, SV, contractility)
increase in BMR (inc in glycogenolysis, gluconeogenesis, lipolysis)
Which hormone stimulates TSH?
TRH
What binds most of the T3/T4 in the blood?
Thyroxine-binding globulin
What provides negative feedback to the anterior pituitary to decrease sensitivity to TRH?
Free T3
Which binds with more affinity, T3 or T4?
T3
What is the Wolff-Chaikoff effect?
Excess iodine temporarily inhibits thyroid peroxidase = decrease iodine organification = decrease T3/T4 production