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3 Cards in this Set
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Regarding opioids, Which is incorrect?
1. Life threatening CNS and resp depression, usually occurring well above the analgesic dose 2. Toxicity is more likely in naive patients or coingestion 3. Opioid intoxication is a leading cause of death in children 4. Presence of seizures and cardiac arrythmias do not exclude an opioid poisoning |
1 is incorrect. Frequently occurs just above the analgesic dose
3. Single opioid tablets can cause resp arrest, or greater than 5mg/kg codeine. 4. Dextropropoxyphene has fast sodium channel blocking effects, pethidine can also cause seizures. Murray 290+ |
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Regarding opioids, which is incorrect:
1. Serotonin synd may be associated 2. Na Bicarb may be indicated 3. activated charcoal is routinely indicated 4. all children with potential opioid ingestion require 12 hrs of monitored observation (unless <2mg/kg codeine) 5. Resp depression may be delayed up to 12 hrs following controlled release morphine OD 6. resp rate should be measured while the patient is sleeping or otherwise undisturbed. |
1. true, pethidine
2. true, for vent arrhythmias secondary to dextropropoxyphene 3. False, supportive care +/- antidote is mainstay 6. in hospitals deaths have occurred due to inadequate monitoring |
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Regarding naloxone, which is incorrect,
1. is indicated for reversal of CNS and resp depression caused by opioids 2. is indicated for empiric treatment for coma, thought to be secondary to opioids 3. 100ug IV may be given Q30secs til spontaneous resp is reestablished 4. doses greater than 400ug are rarely required for partial opioid antagonists, but may be required following heroin OD 5. complete reversal may be appropriate in non opioid dependent individuals 6. partial reversal is appropriate in opioid dependent individuals 7. all patients should be observed for resedation for at least 2 hrs after last dose |
4 incorrect. greater than 400ug is rarely required following heroin OD, but may be required for partial opioid antagonists
6. partial reversal aims for adequate airway protection and resp rate and GCS 13-14 |
