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62 Cards in this Set
- Front
- Back
Characteristics of Epithelia
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1) Line surfaces
2) Avascular 3) Lie upon a basal lamina 4)Demonstrate polarity 5) Often have surface specializations |
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Functions of Epithelia
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1) Protections
2) Transcellular transport 3) Secretion 4) Absorption 5) Selective permeability 6) Detection of sensations |
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Apical Domain
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always directed towards the lumen of the closed tube
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Epithelium
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Lines surfaces exposed to the external world
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Two types of epithelium
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1) Mesothelium
2) Endothelium |
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Mesothelium
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Lines body cavities
simple squamous epithelium |
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Endothelium
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Lines blood vessels
simple squamous epithelium |
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Ectoderm
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epidermis and glands of skin
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Endoderm
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lining of respiratory and GI tracts
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Mesoderm
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Lining of male and female tubes
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Inner lining of kidney tubules
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simple cuboidal epithelium
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Basal Lamina
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Layer of extracellular matrix secreted by the epithelial cells
Attaches cell to connective tissue |
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small intestine
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simple columnar epithelium
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esophagus
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stratified squamous epithelium with moderate keratin
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epidermis
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stratified squmaous epithelium with abundant keratin
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trachea
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pseudostratified columnar ciliated epithelium
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epididymis
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pseudostratified columnar epithelium with sterocilia
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urinary bladder
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transitional epithelium
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simple squamous function
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1) fluid transport
2) gaseous exchange 3) lubrication 4) lining membrane |
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simple cuboidal function
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1) secretion
2) absorption 3) protection |
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simple columnar function
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1) transportation
2) absorption 3) secretion 4) protection |
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characteristics of pseudostratified epithelium
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All cells rest on basal lamina but not all reach epithelial surface
surface cells are columnar |
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pseudostratified function
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1) secretion
2) absorption 3) lubrication 4) protection 5) transportation |
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Stratified squamous (nonkeratinized) function
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1) protection
2) secretion |
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stratified squamous keratinized function
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protection
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stratified cuboidal function
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protection
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stratified columnar function
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secretion, absorption, protection
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Apical domain surface modifications
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1) microvilli
2) cilia 3) stereocilia |
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Microvilli function
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increases surface area for transport and absorption
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cilia function
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motile and move mucus or ova
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sterocilia found in the
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epididymis and hair cells of cochlea
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Axoneme
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9 + 2 arrangement of microtubles
Inside most cilia |
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zonulae occludens
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part of basolateral domain
belt like junction which encircles the cell which separates the luminal space from the intercellular space. Tight junction |
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Zonulae adherentes
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part of basolateral domain
also belt-like. Adherence of adjoining cells |
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Desmosomes (maculae adherentes)
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part of basolateral domain
spot welds. resist shearing forces |
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Gap junctions (nexus)
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regions of intercellular communication
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Hemidesmosomes
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hold base of cell to basal lamina
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Renewal of epithelia
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1) high turnover rate
2) renewed from basal region 3) surface cells die and slough of |
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metaplasia
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transformation of one type of epithelium to another
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carcinoma
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malignancy from epithelia
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adenocarcinoma
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cancer of epithelium that originates in glandular tissue
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unicellular exocrine gland
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goblet cell
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multicellular exocrine gland
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duct + secretory unit
classified according to the organization of their ducts and shape of secretory units simple vs. compound ducts tubular, acinar, or tubuloaveolar secretory units parenchyma vs. stroma |
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Simple multicellular exocrine gland
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duct is unbranched
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compound multicellular exocrine gland
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duct is branched
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tubular multicellular exocrine gland
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secretory portion is shaped like a tube
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alveolar/acinar multicellular exocrine gland
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secretory portion is shaped like a flask
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tubuloalveolar multicellular exocrine gland
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secretory portion is shaped like a saclike dilation
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Different mechanisms of secretion for exocrine glands
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1) merocrine
2) apocrine 3) holocrine |
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Merocrine secretion
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product released via exocytosis
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Apocrine secretion
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some of the apical cytoplasm is pinched off with the contained secretions
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Halocrine secretion
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cell accumulates product and then disintegrates to release secretory material
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type of epithelium visceral peritoneum is
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lines body cavity so it is a mesothelium
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type of epithelium in small blood vessels
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endothelium
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pseudostratified ciliated columnar
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all cells contact the basal lamina
goblet cells and cilia are present typical of trachea and bronchi |
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stereocilia
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long branched microvilli
immobile |
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stereocilia function
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increase surface area for increased absorption of substances from the lumen
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type of epithelium epidermis of the skin is
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stratified squamous epithelium
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stratified columnar epithelium lines
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large-caliber ducts coming from exocrine glands such as salivary glands, pancrease, and sweat glands
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transitional urothelium
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surface of epithelium of bladder appears to be squamous epithelium when bladder is filled but changes to a columnar epithelium when bladder is empty
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goblet cells are found in
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the respiratory and digestive systems
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Microvilli
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have a plasma membrane
increase surface area of the cell |