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62 Cards in this Set

  • Front
  • Back
Characteristics of Epithelia
1) Line surfaces
2) Avascular
3) Lie upon a basal lamina
4)Demonstrate polarity
5) Often have surface specializations
Functions of Epithelia
1) Protections
2) Transcellular transport
3) Secretion
4) Absorption
5) Selective permeability
6) Detection of sensations
Apical Domain
always directed towards the lumen of the closed tube
Epithelium
Lines surfaces exposed to the external world
Two types of epithelium
1) Mesothelium
2) Endothelium
Mesothelium
Lines body cavities

simple squamous epithelium
Endothelium
Lines blood vessels

simple squamous epithelium
Ectoderm
epidermis and glands of skin
Endoderm
lining of respiratory and GI tracts
Mesoderm
Lining of male and female tubes
Inner lining of kidney tubules
simple cuboidal epithelium
Basal Lamina
Layer of extracellular matrix secreted by the epithelial cells

Attaches cell to connective tissue
small intestine
simple columnar epithelium
esophagus
stratified squamous epithelium with moderate keratin
epidermis
stratified squmaous epithelium with abundant keratin
trachea
pseudostratified columnar ciliated epithelium
epididymis
pseudostratified columnar epithelium with sterocilia
urinary bladder
transitional epithelium
simple squamous function
1) fluid transport
2) gaseous exchange
3) lubrication
4) lining membrane
simple cuboidal function
1) secretion
2) absorption
3) protection
simple columnar function
1) transportation
2) absorption
3) secretion
4) protection
characteristics of pseudostratified epithelium
All cells rest on basal lamina but not all reach epithelial surface

surface cells are columnar
pseudostratified function
1) secretion
2) absorption
3) lubrication
4) protection
5) transportation
Stratified squamous (nonkeratinized) function
1) protection
2) secretion
stratified squamous keratinized function
protection
stratified cuboidal function
protection
stratified columnar function
secretion, absorption, protection
Apical domain surface modifications
1) microvilli
2) cilia
3) stereocilia
Microvilli function
increases surface area for transport and absorption
cilia function
motile and move mucus or ova
sterocilia found in the
epididymis and hair cells of cochlea
Axoneme
9 + 2 arrangement of microtubles

Inside most cilia
zonulae occludens
part of basolateral domain

belt like junction which encircles the cell which separates the luminal space from the intercellular space. Tight junction
Zonulae adherentes
part of basolateral domain

also belt-like. Adherence of adjoining cells
Desmosomes (maculae adherentes)
part of basolateral domain

spot welds. resist shearing forces
Gap junctions (nexus)
regions of intercellular communication
Hemidesmosomes
hold base of cell to basal lamina
Renewal of epithelia
1) high turnover rate
2) renewed from basal region
3) surface cells die and slough of
metaplasia
transformation of one type of epithelium to another
carcinoma
malignancy from epithelia
adenocarcinoma
cancer of epithelium that originates in glandular tissue
unicellular exocrine gland
goblet cell
multicellular exocrine gland
duct + secretory unit

classified according to the organization of their ducts and shape of secretory units

simple vs. compound ducts

tubular, acinar, or tubuloaveolar secretory units

parenchyma vs. stroma
Simple multicellular exocrine gland
duct is unbranched
compound multicellular exocrine gland
duct is branched
tubular multicellular exocrine gland
secretory portion is shaped like a tube
alveolar/acinar multicellular exocrine gland
secretory portion is shaped like a flask
tubuloalveolar multicellular exocrine gland
secretory portion is shaped like a saclike dilation
Different mechanisms of secretion for exocrine glands
1) merocrine
2) apocrine
3) holocrine
Merocrine secretion
product released via exocytosis
Apocrine secretion
some of the apical cytoplasm is pinched off with the contained secretions
Halocrine secretion
cell accumulates product and then disintegrates to release secretory material
type of epithelium visceral peritoneum is
lines body cavity so it is a mesothelium
type of epithelium in small blood vessels
endothelium
pseudostratified ciliated columnar
all cells contact the basal lamina

goblet cells and cilia are present

typical of trachea and bronchi
stereocilia
long branched microvilli

immobile
stereocilia function
increase surface area for increased absorption of substances from the lumen
type of epithelium epidermis of the skin is
stratified squamous epithelium
stratified columnar epithelium lines
large-caliber ducts coming from exocrine glands such as salivary glands, pancrease, and sweat glands
transitional urothelium
surface of epithelium of bladder appears to be squamous epithelium when bladder is filled but changes to a columnar epithelium when bladder is empty
goblet cells are found in
the respiratory and digestive systems
Microvilli
have a plasma membrane

increase surface area of the cell