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8 Cards in this Set

  • Front
  • Back
Which is incorrect regarding Cholinergic

poisoning?
A. It is due to over stimulation at the NMJ.
B. It is due to excess Acetylcholine (ACh)
C. There are usually only muscarinic clinical features.


D. The nicotinic receptors are on both Sympathetic and


parasympathetic ganglions.
C. Muscarinic and nicotinic clinical features.
List the Nicotinic receptor stimulation

features in Cholinergic poisoning.
- Mydriasis
- Tachycardia
- Hypertension
- Weakness
- Fasciculations.
What are the 3 life-threatening symptoms / signs of cholinergic poisoning?
Bronchospasm
Bronchorrhoea
Bradycardia
What is the mnemonic for Symptoms and Signs of Cholinergic poisoning ?
"Sludge and Killer Bees" OR "Dumbels"

Salivation Bronchorrhoea
Lacrimation Bronchospasm
Urinary incontinence Bradycardia
Defaecation
GIT pain (abdominal pain )
Emesis

Defaecation -Diarrhoea
Urination
Muscle weakness + Miosis
Bradycardia + Bronchospasm

+ Bronchorrhoea
Emesis
lacrimation
Salivation
Which is not typically a Clinical feature of

Cholinergic poisoning ?



A. Tachycardia
B. Urine retention
C. Vomiting
D. Diarrhoea
B. Urinary incontinence

Tachycardia ( Nicotinic) or Bradycardia

( muscarinic ) can occur
Which is correct regarding Anticholinergic

poisoning?
A. It is due to blockage of ACh receptors in the PNS only.
B. Miosis occurs.
C. Reduced bowel sounds - Ileus is a feature.
D. Urinary incontinence occurs.
C.

A = PNS and CNS ACh receptor blockage.
B = Mydriasis
D = Urine retention
List the Features of Anticholinergic poisoning .
Fever " Hot as Hades"
Tachycardia " fast as a ferret"
Mydriasis and cycloplegia

(loss of accommodation) " Blind as a bat"
Cessation of perspiration / xerostomia
"Dry as a bone"
Flushing "red as a beet"
Delerium "Mad as a Hatter"
Urine retention + Ileus " Stuffed as a pipe".
Which is incorrect regarding Cholinergic

poisoning ?
A. Ageing does not occur with Carbamates
B. The management of carbamate overdose is the same as organophospahte poisoning .
C. Physostigmine and Pyridostigmine are cholinesterase inhibitors that reversibly inhibit the cholinesterase enzyme.
D. Carbamates do not penetrate the CNS.
B. Atropine is used for both.


However, due to ageing not occurring with


carbamates, pralidoxime use is controversial with carbamates.