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36 Cards in this Set
- Front
- Back
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What type of organism are the Chlamydiae?
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Obligate intracellular
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What intracellular constituents make up Chlamydiae?
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-DNA
-RNA -Prokaryotic ribosomes |
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Can Chlamydiae make their own ATP?
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No
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Are Chlamydiae susceptible to penicillin?
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No
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What does it mean to say Chlamydiae have a dimorphic developmental cycle?
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They exist in two forms:
-Elementary bodies -Reticulate bodies |
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What are the features of Elementary bodies?
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They are the infectious form of Chlamydia but not capable of division.
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What are the features of the reticulate bodies?
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They are what divide, but are not infectious.
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How does Chlamydia multiply?
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1. Elem bodies infect a host cell
2. Transform into reticulate bodies 3. Reticulate bodies replicate 4. Host cell lysis releases the EB's to infect other host cells |
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What disease is caused by Chlamydia psittaci? How is it transmitted?
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Ornithosis (psittacosis)
-Transmitted via aspiration of birdpoop |
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What disease is caused by Chlamydia pneumoniae? How is it transmitted?
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Mild pneumonia
-Transmitted via person-to- person aerosols |
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What disease is caused by Chlamydia trachomatis types A/B/Ba/C? How is it transmitted?
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Trachoma
-Transmitted via repeated contact, fomites, insects. |
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What disease is caused by Chlamydia trachomatis types D-K? How is it transmitted?
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Inclusion conjunctivitis, nongonorrheal and postgonorrheal urethritis, proctitis, pharyngitis, cervicitis, and arthritis
-All STDs or birth canal |
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What disease is caused by Chlamydia trachomatis types L1,L2, and L3? How is it transmitted?
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Lymphogranuloma venereum
-Transmitted via sex |
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What can you NOT treat nongonorrheal urethritis with?
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Penicillin - chlamydia is not susceptible to it.
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What does Follicular conjunctivitis mean?
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Inclusions are seen in the conjunctiva - follicles - bubblies
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What is the triad of Reiter syndrome?
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-Conjunctivitis
-Polyarthritis -Genital infection |
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And what agent causes the STDs of Chlamydia?
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Chlamydia trachomatis types D-K
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Does chlamydia Trachomatis types A-C cause STD related disease?
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NO
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What will be seen in Chlamydial cervicitis?
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Pus around the opening of the cervix
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Is visualization of pus on the cervix diagnostic of chlamydia? Why?
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No - because it could be a dual infection of chlamydia and GC simultaneously.
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Because Chlamydia is the most common STD in the world, what is done when pus is seen on the cervix?
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Empirical treatment
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What is Trachoma? What agent causes it?
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Chronic suppurative eye disease
-Caused by Chlamydia trachomatis types A-B-Ba-C |
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Why is Trachoma bad?
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It is the LEADING infectious cause of blindness WORLDWIDE.
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How is trachoma transmitted?
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-Direct human contact
-Fomites -Flies |
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Where is trachoma primarily seen?
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In dry sandy regions among poor people and nomads.
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How is the pannus/scarring due to Trachoma treated?
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Surgically
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What are 3 diseases caused by Rickettsiae?
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-Epidemic typhus
-Scrub typhus -Spotted fevers |
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What cells are the targets of Rickettsiae?
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-Endothelial cells
-Vascular smooth muscle cells |
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What symptoms result from Rickettsiae infections?
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-Rash
-Vasculitis -Thrombi -Hemorrhage |
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How is Rickettsiae infection diagnosed?
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Via immunostaining in tissue
Via serologic techniques |
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What is the causative agent of Rocky mountain spotted fever?
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Rickettsiae rickettsii
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What is the transmission vector of R. rickettsii?
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Ticks
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where is rash seen in RMSF?
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On the palms and soles
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What else do ticks transmit?
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Ehrlichiosis
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What agent causes Ehrlichiosis?
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Ehrlichia sennetsu and canis
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What are the symptoms of Ehrlichiosis?
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-Fever
-Lymphadenopathy -no eschar or rash |
